Abstract:
:In this study, the genotoxic effects of a widely used herbicide, trifluralin, and its commercial formulation, Treflan, were evaluated using the micronucleus test in a commercially important fish species, Oreochromis niloticus (Nile Tilapia). Fish were exposed to 1, 5, and 10 microg/L doses of trifluralin and Treflan for 3, 6, and 9 days under laboratory conditions. Ethylmethanesulfonate, at a single dose of 10 mg/L, was used as positive control. Micronuclei were evaluated on the peripheral erythrocytes. Both Treflan and trifluralin treatments significantly increased the micronucleus frequencies in peripheral erythrocytes of O. niloticus. Furthermore, the genotoxicity of the active ingredient, trifluralin, was observed to be higher than that of the commercial formulation Treflan. Our results indicate that herbicide trifluralin has genotoxic potential in fish.
journal_name
Environ Mol Mutagenjournal_title
Environmental and molecular mutagenesisauthors
Könen S,Cavaş Tdoi
10.1002/em.20401subject
Has Abstractpub_date
2008-07-01 00:00:00pages
434-8issue
6eissn
0893-6692issn
1098-2280journal_volume
49pub_type
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