Effect of protein restriction diet on renal function and metabolic control in patients with type 2 diabetes: a randomized clinical trial.

Abstract:

OBJECTIVE:To assess the effect of a low protein diet (LPD) on renal function and metabolic control in three sub-groups of patients with type 2 diabetes those with or without nephropathy. RESEARCH DESIGN AND METHODS:A randomized clinical trial was conducted on 60 patients with type 2 diabetes in primary care -19 with normoalbuminuria, 22 with microalbuminuria, and 19 with macroalbuminuria-. All patients experienced a screening phase during the 3 months, and were designated according to percentages of daily caloric intake (e.g., carbohydrates 50%, fat 30%, and 20% of protein). After this period, they were randomly assigned to receive either LPD (0.6-0.8 g/kg per day) or normal protein diet (NPD) (1.0-1.2 g/kg per day) for a period of 4 months. Twenty nine patients received LPD and 31 received NPD. Primary endpoints included measures of renal function (UAER, serum creatinine and GFR) and glycemic control (fasting glucose and glycosylated hemoglobin A1c). RESULTS:Renal function improved among patients with macroalbuminuria who received LPD: UAER decreased (1,280.7 +/- 1,139.7 to 444.4 +/- 329.8 mg/24 h; p < 0.05) and GFR increased (56.3 +/- 29.0-74.2 +/- 40.4 ml/min; p < 0.05). In normoalbuminuric and microalbuminuric patients, there were no significant changes in UAER or GFR after either diet. HbA1c decreased significantly among microalbuminuric patients on both diets (LPD, 8.2 +/- 1.6-7.2 +/- 1.8%; p < 0.05; NPD, 8.8 +/- 1.9-7.1 +/- 0.8%; p < 0.05) and among macroalbuminuric patients who received NPD (8.1 +/- 1.8-6.9 +/- 1.6%; p < 0.05). CONCLUSIONS:A moderated protein restriction diet improved the renal function in patients with type diabetes 2 and macroalbuminuria.

journal_name

Nutr Hosp

journal_title

Nutricion hospitalaria

authors

Velázquez López L,Sil Acosta MJ,Goycochea Robles MV,Torres Tamayo M,Castañeda Limones R

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

141-7

issue

2

eissn

0212-1611

issn

1699-5198

pii

S0212-16112008000200011

journal_volume

23

pub_type

杂志文章,随机对照试验
  • [Effect of the ingestion of food and gynecologic risk factors on breast cancer risk in Valencia].

    abstract:OBJECTIVES:The present case-control study was undertaken to elucidate the role of recent diet, specially in the influence of food groups, in the development of cancer of the breast. MATERIAL AND METHODS:A case-control study of breast cancer (BC) was conducted between April to November 1997 in Valencia (Spain). Cases w...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Morales Suárez-Varela M,Jiménez López MC,Almenar Cubells D,Llópis González A

    更新日期:1998-11-01 00:00:00

  • [Benefits, efficacy, and risk associated with the conventional treatment of obesity: should we treat the weight excess?].

    abstract::The literature contains a large number of published articles indicating a strong relationship between obesity and morbidity-mortality due to different cause. There are also various short- to medium-term studies demonstrating the benefits of a moderate weight loss on the control of obesity-related risk factors. Nonethe...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,评审

    doi:

    authors: Salas i Salvadó J

    更新日期:2002-02-01 00:00:00

  • Oral glucose and breast milk as a strategy for pain reduction during the heel lance procedure in newborns.

    abstract:INTRODUCTION:This paper presents the results of a study on pain reduction in newborns that undergo painful medical procedures. This research analyzed the reactions of babies before and after the heel lance procedure, a diagnostic test performed to detect phenylketonuria. This test involved the extraction of a capillary...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2014.30.5.7862

    authors: Aguilar Cordero MJ,Mur Villar N,García García I,Rodríguez López MA,Rizo Baeza MM

    更新日期:2014-11-01 00:00:00

  • [A descriptive analysis of the use of the parenteral nutrition protocol in an area hospital].

    abstract::A retrospective study was carried out of all the Parenteral Nutrient Units (PNUs) prepared in the Pharmacy Service (PS) of an Area Hospital with 378 beds, over a four-year term (1988-1991), with the aim of describing the use of Parenteral Nutrition (PN) and to find out to what level it is adjusted to the established m...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Iranzo Fernández MD,Argamasilla Molina MP,Mira Sirvent MC,Llimera Rausell G

    更新日期:1993-07-01 00:00:00

  • Trans fatty acids (tFA): sources and intake levels, biological effects and content in commercial Spanish food.

    abstract::Recent studies of dietary habits in children and adolescents performed in Spain show that a high percentage of the daily energy intake corresponds to fat (42.0-43.0%). These findings show an excessive contribution of saturated fatty acids and also a considerable supply of trans fatty acids. These compounds are formed ...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Fernández-San Juan PM

    更新日期:2009-09-01 00:00:00

  • The use of biochemical and immunological parameters in nutritional screening and assessment.

    abstract:OBJECTIVE:To evaluate the relationship between serum albumin, total cholesterol and total lymphocyte count with two nutritional assessment methods, to verify if their use is justified in nutritional screening tools. METHODS:101 patients admitted to medical/surgical wards underwent the SGA and the Full Nutritional Asse...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.1590/S0212-16112011000300024

    authors: González Madroño A,Mancha A,Rodríguez FJ,de Ulibarri JI,Culebras J

    更新日期:2011-05-01 00:00:00

  • TRAQUEOESOPHAGEAL FISTULA PATIENTS FED THROUGH PERCUTANEOUS ENDOSCOPIC GASTROSTOMY/GASTROJEJUNOSTOMY: NUTRITIONAL STATUS AND CLINICAL OUTCOME.

    abstract:BACKGROUND:tracheoesophageal fistula (TEF) may result from cancer or mechanical ventilation. Endoscopic Gastrostomy or Gastrojejunostomy (PEG/PEG-J) is used for nutritional support. OBJECTIVE:in TEF-patients, evaluating nutritional status when PEG is performed, safety of PEG/PEG-J and clinical outcome. METHODS:from t...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2015.32.2.9078

    authors: Santos CA,Pereira M,Martins VS,Fonseca J

    更新日期:2015-08-01 00:00:00

  • [Levels of obesity, fasting glycemia and physical condition in Chilean students].

    abstract:BACKGROUND:Chile has drastically altered eating patterns and physical activity. The main nutritional problem faced by Chilean society is overweight, which arises progressively from an early age. The aim of this study is to determine the nutritional status and compare fitness levels and fasting glucose in students. PAT...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2015.31.6.8932

    authors: Delgado Floody P,Caamaño Navarrete F,Guzmán Guzmán IP,Jerez Mayorga D,Ramírez-Campillo R,Campos Jara C,Ríos Lagos G,Díaz Inostroza H

    更新日期:2015-06-01 00:00:00

  • [Causes and components of the metabolic syndrome in renal transplant recipients from a gender perspective].

    abstract:INTRODUCTION:the appearance of metabolic syndrome (MS) among renal recipients is one of the greatest post-transplant complications and is associated with an increased risk of graft failure and high rates of obesity and new onset diabetes. OBJECTIVE:the objective of this work is to identify the relationship between the...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.1717

    authors: Martín Salvador A,Fernández Castillo R,García García I,Aguilar Cordero MJ,Bravo Soto J

    更新日期:2018-10-05 00:00:00

  • [Relation between leptin serun with weight and body fat distribution in postmenopausal women].

    abstract:UNLABELLED:Leptin is a peptidic hormone secreted by the fat tissue and plays an important role in body weight regulation. After menopause, weight gain increases as well as android-like obesity. Previous studies suggest a relationship between leptin level, body mass index (BMI) and fat distribution. OBJECTIVE:To establ...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Barrios Ospino Y,Díaz N,Meertens L,Naddaf G,Solano L,Fernández M,Flores A,González M

    更新日期:2010-01-01 00:00:00

  • [Cardiometabolic risk and variation of fat/adipose content according to body mass index in children from six to nine years old].

    abstract:Introduction:Introduction: child excess weight has been associated with obesity in adulthood and, as a consequence, increased risk of death due to cardiometabolic factors. Objective: to identify whether BMI reflects changes in the content and distribution of fat/adipose tissue and the cardiometabolic risk in children b...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.2071

    authors: López Fuenzalida A,Illanes Aguilar L,Rodríguez Canales C,Contreras-Briceño F,Durán Agüero S,Herrera-Valenzuela T,Valdés-Badilla PA

    更新日期:2019-04-10 00:00:00

  • [Nutritional assessment of a university population].

    abstract::In this work, we have planned to perform a nutritional assessment of a group of 50 students from the University of Granada, to which questionnaires have been administered relating to 24-hour remembrance of type and frequency of food consumption, for 30 days. In order to know macro- and micronutrients intake, the resul...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Oliveras López MJ,Nieto Guindo P,Agudo Aponte E,Martínez Martínez F,López García de la Serrana H,López Martinéz MC

    更新日期:2006-03-01 00:00:00

  • [VALUES OF WAIST/HIP RATIO AMONG CHILDREN AND ADOLESCENTS FROM BOGOTÁ, COLOMBIA: THE FUPRECOL STUDY].

    abstract:OBJECTIVE:the aim was to establish reference standards for waist/hip ratio among Colombia children and adolescent aged 9 to 17.9 years who participated in "The FUPRECOL Study". METHODS:cross-sectional study. A sample of 3 005 children and 2 916 adolescents healthy Colombian youth (boys n = 2 542 and girls n = 3 384) p...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2015.32.5.9633

    authors: Rodríguez-Bautista YP,Correa-Bautista JE,González-Jiménez E,Schmidt-RioValle J,Ramírez-Vélez R

    更新日期:2015-11-01 00:00:00

  • [Effect of an oral hyperproteic nutritional supplement in malnourished elderly patients in nursing homes].

    abstract:INTRODUCTION:Nutritional problems develop complications in geriatric patients and increase their morbidity and mortality. Hyperproteic nutritional supplements are one of the options to improve nutritional deficiencies. OBJECTIVES:To assess the beneficial effect and tolerance of one hyperproteic nutritional supplement ...

    journal_title:Nutricion hospitalaria

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Ordóñez J,De Antonio Veira JA,Pou Soler C,Navarro Calero J,Rubio Navarro J,Marcos Olivares S,López Ventura M

    更新日期:2010-07-01 00:00:00

  • Body composition changes after sport detraining period

    abstract:Introduction:The infl uence of exercise in trained subjects has beneficial effects in the physical fi tness and body composition; however, detraining has an unfavorable effect in all of them. Objective:The current study was designed to ascertain the infl uence of a six week-detraining period on body composition in bot...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.618

    authors: Alvero Cruz JR,Ronconi M,García Romero JC,Carrillo de Albornoz Gil M,Jíménez López M,Correas Gómez L,Álvarez Carnero E

    更新日期:2017-06-05 00:00:00

  • Home enteral nutrition in children: a 10 year experience with 304 pediatric patients.

    abstract:BACKGROUND & AIMS:Home enteral nutrition is used increasingly in pediatric populations. Our objective was to describe the profile of pediatric patients requiring this treatment. MATERIAL AND METHODS:All patients under 18 years old requiring treatment with home enteral nutrition between January 1995 and December 2004 w...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2012.27.5.5898

    authors: Pedrón-Giner C,Calderón C,Martínez-Zazo A,Cañedo Villaroya E,Malillos González P,Sesmero-Lillo MÁ

    更新日期:2012-09-01 00:00:00

  • [Weight-for-age percentile curves for the population of Catamarca province (Argentina)].

    abstract:INTRODUCTION:The assessment of fetal development and birth weight is a priority in the field of nutritional epidemiology and public health. Nowadays, the World Health Organization (WHO) does not have specific birth weight curves for the distinct gestational weeks considering that socio-economic, ecological and ethnic c...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2015.31.2.7722

    authors: López Barbancho D,Terán de Frutos JM,Candelas González N,Díaz de Luna MC,Marrodán Serrano MD,Lomaglio DB

    更新日期:2014-09-12 00:00:00

  • The nutritional status in adolescent Spanish cyclists.

    abstract:INTRODUCTION:Adolescence is an important period of nutritional vulnerability due to the increased dietary requirements. OBJECTIVE:To describe the nutritional status of adolescent cyclist and a group of normoactive controls. METHODS:The HELENA Dietary Assessment Tool was used to evaluate the nutritional intake of 20 a...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2013.28.4.6513

    authors: Julián-Almárcegui C,Gómez-Cabello A,González-Agüero A,Olmedillas H,Gómez-Bruton A,Matute-Llorente A,Casajús JA,Vicente-Rodríguez G

    更新日期:2013-07-01 00:00:00

  • [Not Available].

    abstract:UNLABELLED:Introducción y objetivos: las enfermedades cardiovasculares (ECV) son la principal causa de muerte mundial, por ello el objetivo de este estudio es analizar los factores de riesgo de ECV en los trabajadores de la Universidad de Alicante.Material y métodos: estudio transversal descriptivo. Muestra aleatoria (...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.273

    authors: Norte Navarro AI,Sansano Perea M,Martínez Sanz JM,Sospedra López I,Hurtado Sánchez JA,Ortiz Moncada R

    更新日期:2016-06-30 00:00:00

  • [Meal replacement efficacy on long-term weight loss: a systematic review].

    abstract:UNLABELLED:Meal replacement (MR) has been frequently used to substitute one or more meals during the day. However, few randomized long-term studies have assessed its efficacy. OBJECTIVE:To asses meal replacement use and its effectiveness on long-term weight loss (> 1 year) in overweight and obese people with or withou...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,meta分析,评审

    doi:10.1590/S0212-16112011000600011

    authors: López Barrón G,Bacardí Gascón M,De Lira García C,Jiménez Cruz A

    更新日期:2011-11-01 00:00:00

  • [Prevalence and sociodemographic factors associated with iron deficiency anemia in pregnant women of Colombia (secondary analysis of the ENSIN 2010)].

    abstract:Introduction:Objective: iron deficiency anemia is associated with adverse results for health and it is highly prevalent worldwide. The current study evaluated the prevalence and the sociodemographic factors associated with iron deficiency anemia in a sample of Colombian pregnant women. Materials and methods: the second...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.1895

    authors: Rincón-Pabón D,Urazán-Hernández Y,Gonzalez-Santamaria J

    更新日期:2019-03-07 00:00:00

  • [Prevention of the refeeding syndrome].

    abstract::The refeeding syndrome can be defined as the metabolic alterations developed by the rapid nutrition repletion (oral, enteral as well as parenteral feeding) of severaly malnourished patients. Refeeding syndrome is a potentially fatal clinical condition and it is often underdiagnosed on non-specialized nutrition units. ...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Martínez Núñez ME,Hernández Muniesa B

    更新日期:2010-11-01 00:00:00

  • Rice bran supplementation during nutritional recovery period of malnourished rats improves colon development.

    abstract:OBJECTIVE:To investigate the colon's development in rats subjected to protein energy malnutrition followed by supplementation with rice bran. MATERIALS AND METHODS:Weaned Wistar male rats (21 days old), weight (40-50 g) were divided into two groups: diet with 17% protein (C; control group) or an aproteic diet (A; apro...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Martins MS,Dores EF,Aguilar-Nascimento JE,Oyama LM,Latorraca MQ,Gomes-da-Silva MH,do Nascimento CM

    更新日期:2007-11-01 00:00:00

  • Dietary intake according to hydration status in 9-10 year-old soccer players.

    abstract:INTRODUCTION:Children have an increased risk of voluntary dehydration especially during physical activity which may increase the risk of non-compensating water losses. OBJECTIVES:The aim of this study was to assess the hydration status and its relation to food intake in a children group of soccer players. METHOD:A sa...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.315

    authors: Rodriguez L,Azevedp AR,Seabra A,Padrao P,Moreira P

    更新日期:2016-07-13 00:00:00

  • Behavioural therapy in the treatment of obesity (II): role of the Mediterranean diet.

    abstract:OBJECTIVES:Obesity is the consequence of an imbalance between energy intake and expenditure, food intake being affected by multiple factors -psychological, social, work-related, etc. This revision discusses the role of diet in the behavioural treatment (BT) of obesity, which faces multiple approaches and focuses on pat...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,评审

    doi:

    authors: Garaulet M,Pérez de Heredia F

    更新日期:2010-01-01 00:00:00

  • Sociodemographic and dietary profile of 4,471 childbearing-age women planning a pregnancy.

    abstract:BACKGROUND:The maintenance of healthy lifestyles is of great importance to prevent pregnancy-related diseases at early stages. For this reason, the knowledge of the overall wellbeing of women at childbearing-age is necessary to provide appropriate advice to maintain or improve the nutritional status. The aim of this re...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2014.29.2.7082

    authors: Cuervo M,Goni L,Santiago S,Zazpe I,García A,Martínez JA

    更新日期:2014-02-01 00:00:00

  • [Multicenter study on incidence of total parenteral nutrition complications in the critically-ill patient. ICOMEP study. Part II].

    abstract:OBJECTIVE:To assess enteral nutrition complications in a prospective cohort of patients admitted to the ICU. MATERIAL AND METHODS:Prospective, multicenter study of patients admitted to the ICU and that received enteral nutrition (EN). Demographical data, main diagnosis, and nutritional and severity indexes were includ...

    journal_title:Nutricion hospitalaria

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Grau T,Bonet A,Grupo de Trabajo de Metabolismo y Nutrición de la Sociedad Española de.,Medicina Intensiva Critica y Unidades Coronarias.

    更新日期:2005-07-01 00:00:00

  • [Nutrition and colorectal cancer].

    abstract::Colorectal cancer is the most common tumor behind lung cancer in men and breast cancer in women. Its prevalence shows a wide geographic variability, which, along with epidemiological and experimental evidence, suggests a considerable participation of environmental factors, mainly dietary in its cause. It is not known ...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,评审

    doi:

    authors: Jorquera Plaza F,Culebras Fernández JM

    更新日期:2000-01-01 00:00:00

  • [Phospholipids: properties and health effects].

    abstract::Phospholipids are amphipathic lipids, which are found in all the cell membranes, organized as a lipid bilayer. They belong to the glycerol-derived lipids, showing a similar structure as triglycerides. The current interest of them comes from its effectiveness to incorporate different fatty acids in the cell membrane, a...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,评审

    doi:10.3305/nh.2015.31.1.7961

    authors: Torres García J,Durán Agüero S

    更新日期:2014-09-12 00:00:00

  • [Satisfaction rating in a group of women from Granada on birthing care, support and breastfeeding length].

    abstract:INTRODUCTION:The satisfaction's analysis is being used as an instrument to create different sanitary reforms to improve the quality and numerous studies aim to the increase the mother's satisfaction directly related to the maternity care. OBJECTIVES:[corrected] Identify the woman satisfaction's degree about birth atte...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.3305/nh.2013.28.3.6395

    authors: Aguilar Cordero MJ,Sáez Martín I,Menor Rodríguez MJ,Mur Villar N,Expósito Ruiz M,Hervás Pérez A,González Mendoza JL

    更新日期:2013-05-01 00:00:00