Are chronic dialysis patients at increased risk for cancer?

abstract：:The partial correction of anemia and the normalization of phosphate and blood pressure are the mainstay of treatment of patients with chronic kidney disease (CKD). Available anti-hypertensive drugs, erythropoiesis stimulating agents (ESAs) and iron supplements have resolved quite satisfactorily the goal of controlling...

journal_title：Journal of nephrology

authors： Locatelli F,Del Vecchio L

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Removal of anti-glomerular basement membrane (anti-GBM) antibody by extracorporeal treatment including plasmapheresis or immunoadsorption (IA) has been considered an effective method in the treatment of Goodpasture's syndrome. In this study, we investigated the effect of IA on serum anti-GBM level and evalua...

journal_title：Journal of nephrology

authors： Hu W,Liu Z,Ji D,Xie H,Gong D,Li L

更新日期：2006-05-01 00:00:00

abstract：:Preemptive isolated liver transplantation (PLTX) can cure the metabolic defect in primary hyperoxaluria type 1 (PH1) but there are no uniformally accepted recommendations concerning the timing of this transplantation procedure. We have performed PLTX successfully in 4 children (age 3-9 years) with PH1 with no mortalit...

journal_title：Journal of nephrology

authors： Kemper MJ,Nolkemper D,Rogiers X,Timmermann K,Sturm E,Malago M,Broelsch CE,Burdelski M,Müller-Wiefel DE

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:To report clinical symptoms and outcome of systemic paraphenylene diamine (PPD) intoxication. METHODS:Our study was retrospective. It was conducted over 6 yrs (1994-2000) in the medical intensive care unit (ICU) of a university hospital and it concerned 19 patients hospitalized for systemic PPD intoxication...

journal_title：Journal of nephrology

authors： Kallel H,Chelly H,Dammak H,Bahloul M,Ksibi H,Hamida CB,Chaari A,Rekik N,De Broe ME,Bouaziz M

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is an important risk factor for all-cause mortality. In the general population, physical activity is associated with reduced mortality. We examined the association of level of physical activity with mortality in patients with predominantly nondiabetic CKD stage 3-4. METHODS:We s...

journal_title：Journal of nephrology

authors： Chen JL,Lerner D,Ruthazer R,Castaneda-Sceppa C,Levey AS

更新日期：2008-03-01 00:00:00

abstract：:Hyperlipidaemia complicating the nephrotic syndrome is characterised by elevated levels of total and LDL cholesterol, often with hypertriglyceridaemia and low HDL cholesterol levels. The underlying mechanisms are complex but involve abnormalities of both lipoprotein synthesis and catabolism. Experience to date suggest...

journal_title：Journal of nephrology

authors： Wheeler DC

更新日期：2001-11-01 00:00:00

abstract：:With increasingly accurate non-invasive tests, the clinician frequently discovers obstruction of the renal arteries by atherosclerosis. The decision to reverse this obstruction is not straightforward, particularly when blood pressure can be easily controlled with medications. Proper management of this problem requires...

journal_title：Journal of nephrology

authors： Middleton JP

更新日期：1998-05-01 00:00:00

abstract：:The widely differing functions of vitamin D are based both on a wide diffusion of its specific receptor (VDR) and on the ability of many cells, in addition to renal tubular cells, to synthesize calcitriol for autocrine and paracrine functions. In the last few years, many published studies have added new insights into ...

journal_title：Journal of nephrology

authors： Messa P,Alfieri C,Rastaldi MP

更新日期：2011-05-01 00:00:00

abstract：:The pathogenesis of calcium-oxalate (CaOx) renal stones is still debated and a number of issues needs to be clarified. In particular, it is difficult to combine the intraluminal physical-chemical imbalance and fixed particle theory with the evidence that CaOx stones actually form and grow on Randall's plaque in the re...

journal_title：Journal of nephrology

authors： Gambaro G,D'Angelo A,Fabris A,Tosetto E,Anglani F,Lupo A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Mesangial proliferative glomerulonephritis (MePGN) is characterized by excessive mesangial cell proliferation and mesangial matrix expansion, which lead to glomerular sclerosis and obliteration and, in turn, to deteriorating renal function. To identify and quantify the total proteins in renal tissues of MePG...

journal_title：Journal of nephrology

authors： Sui W,Tang D,Zou T,Zou G,Chen J,Li H,Li L,Hou Y,Li H,Dai Y

更新日期：2013-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is now considered a systemic disease due to the occurrence of extra-hepatic manifestations. Among these, the renal involvement is frequent. HCV infection, in fact, is strongly associated with proteinuria and chronic kidney disease (CKD) and negatively affects the prognosis of renal pa...

journal_title：Journal of nephrology

authors： Minutolo R,Aghemo A,Chirianni A,Fabrizi F,Gesualdo L,Giannini EG,Maggi P,Montinaro V,Paoletti E,Persico M,Perticone F,Petta S,Puoti M,Raimondo G,Rendina M,Zignego AL,Italian Society of Nephrology (SIN).,Italian Associat

更新日期：2018-10-01 00:00:00

abstract：:Recently, two independent teams detected presumed hepatitis agents, which were designated HGV and hepatitis GB virus C; they represent a new genus in the family Flaviviridae. The most accurate way to assess the epidemiology of GBV-C/HGV infection remains the combination of RT-PCR and anti-GBV-C/HGV E2 techniques, to d...

journal_title：Journal of nephrology

authors： Fabrizi F,Martin P

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Incremental dialysis may preserve residual renal function and improve survival in comparison with full-dose dialysis; however, available evidence is limited. We therefore compared all-cause mortality and residual kidney function (RKF) loss in incremental and full-dose dialysis and time to full-dose dialysis ...

journal_title：Journal of nephrology

authors： Garofalo C,Borrelli S,De Stefano T,Provenzano M,Andreucci M,Cabiddu G,La Milia V,Vizzardi V,Sandrini M,Cancarini G,Cupisti A,Bellizzi V,Russo R,Chiodini P,Minutolo R,Conte G,De Nicola L

更新日期：2019-10-01 00:00:00

abstract：:End-stage renal disease (ESRD) is a significant global health problem that places a considerable burden on health care resources. The leading cause of death in ESRD patients is cardiovascular disease, which is often preceded by changes in cardiac geometry, including left ventricular hypertrophy (LVH). Treatments that ...

journal_title：Journal of nephrology

authors： Culleton BF,Asola MR

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Changes in podocyte phenotype and function are characteristic of proteinuric glomerular diseases. Integrin-linked kinase (ILK) functions as a common downstream effector in proteinuric diseases. In addition, ILK was shown to interact with the Wnt signaling pathway. Here, we investigated ILK expression as well...

journal_title：Journal of nephrology

authors： Naves MA,Requião-Moura LR,Soares MF,Silva-Júnior JA,Mastroianni-Kirsztajn G,Teixeira VP

更新日期：2012-05-01 00:00:00

abstract：:One of the central functions of the kidney is to excrete low molecular weight, water soluble, plasma, waste products into the urine, whereas macromolecules, the size of albumin and larger, are retained. The flow of the glomerular filtrate is thought to follow an extracellular route, passing through the endothelial fen...

journal_title：Journal of nephrology

authors： Nosadini R,Tonolo G

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Phosphate control is a crucial treatment goal in end-stage renal disease, but poor patient adherence to phosphate binder therapy remains a challenge. This study aimed to estimate the extent of phosphate binder adherence in hemodialysis patients and to identify potential determinants. METHODS:Phosphate binde...

journal_title：Journal of nephrology

authors： Van Camp YP,Vrijens B,Abraham I,Van Rompaey B,Elseviers MM

更新日期：2014-12-01 00:00:00

abstract：:Bisphosphonates inhibit bone resorption and are widely used to treat osteolytic metastases and osteoporosis. Renal osteodystrophy patients have continuous bone loss due to chronically elevated parathyroid hormone (PTH). In this open-label study, ibandronate was evaluated for the treatment of reduced bone density in re...

journal_title：Journal of nephrology

authors： Bergner R,Henrich D,Hoffmann M,Schmidt-Gayk H,Lenz T,Upperkamp M

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Functional failure of the peritoneal membrane is the most serious problem in long-term continuous ambulatory peritoneal dialysis (CAPD). Transforming growth factor-beta (TGF-ss) is one of the key mediators of fibrosis in some organs, and is thought to be involved in peritoneal alterations. In this study, we ...

journal_title：Journal of nephrology

authors： Naiki Y,Maeda Y,Matsuo K,Yonekawa S,Sakaguchi M,Iwamoto I,Hasegawa H,Kanamaru A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Rituximab (RTX) is approved for remission induction in ANCA associated vasculitis (AAV). However, data on use of RTX in patients with severe renal disease is lacking. METHODS:We conducted a retrospective multi-center study to evaluate the efficacy and safety of RTX with glucocorticoids (GC) with and without...

journal_title：Journal of nephrology

authors： Geetha D,Hruskova Z,Segelmark M,Hogan J,Morgan MD,Cavero T,Eriksson P,Seo P,Manno RL,Dale J,Harper L,Tesar V,Jayne DR

更新日期：2016-04-01 00:00:00

abstract：:We report 4 cases of sepsis-induced acute renal failure (ARF) with peculiar clinical presentation in which the renal biopsy was the only clue to a correct diagnosis. We observed 66 cases of ARF in a 4-year experience. Seven (11%) were associated with sepsis; in 3 of these (4.5%) a shock was present. Clinical picture o...

journal_title：Journal of nephrology

authors： Feriozzi S,Muda AO,Massimetti C,Costantini S,Ancarani E

更新日期：1998-09-01 00:00:00

abstract：:The metabolic syndrome is a cluster of cardiometabolic alterations at least partly dependent on reduced insulin sensitivity and hyperinsulinemia that can have several renal implications. A systematic review and meta-analysis of studies available in the international literature in English language demonstrates that the...

journal_title：Journal of nephrology

authors： Rendina D,De Filippo G,D'Elia L,Strazzullo P

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Cell-free DNA (cfDNA) is present in the peritoneal effluent of stable peritoneal dialysis (PD) patients, but there are no data on cfDNA in PD patients with peritonitis. We investigated the variation of peritoneal cfDNA levels subsequent to peritonitis in PD patients. METHODS:We enrolled 53 PD patients: 30 w...

journal_title：Journal of nephrology

authors： Virzì GM,Milan Manani S,Brocca A,Cantaluppi V,de Cal M,Pastori S,Tantillo I,Zambon R,Crepaldi C,Ronco C

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The effect of interleukin-11 (IL-11) on transforming growth factor-ß (TGF-ß) is controversial and has not been examined in renal diseases. In this study, we (i) characterised the up-regulation of TGF-ß1, phospho-p38 MAPK (p-p38 MAPK) and extracellular matrix during pathogenesis of glomerulonephritis and (ii)...

journal_title：Journal of nephrology

authors： Stangou M,Bhangal G,Lai PC,Smith J,Keith JC Jr,Boyle JJ,Pusey CD,Cook T,Tam FW

更新日期：2011-01-01 00:00:00

abstract：:Modern nephrology developed in Poland mostly from the internal medicine department chaired in Warsaw by the great internist prof. Witold Orłowski (1874-1966). Three of his pupils Tadeusz Orłowski, Jan Roguski and Jakub Penson independently established the foundations of clinical nephrology and renal replacement therap...

journal_title：Journal of nephrology

authors： Czekalski S,Rutkowski B

更新日期：2006-05-01 00:00:00

abstract：:Klaus Hierholzer (1929-2007) dissected various functions influenced by steroids in the distal tubule and showed that aldosterone in low doses reversed the sodium and potassium transport defect in adrenalectomized rats, through a rapid activation of Na+,K+-ATPase. Subsequent studies addressed the role of 11-beta-hydrox...

journal_title：Journal of nephrology

authors： De Santo NG,Fromm M,Russo F,Wiederholt M

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) geometric patterns have never been evaluated as independent risk factors for renal disease progression (RDP). We investigated the risk factors for RDP in type 2 diabetic nephropathy patients, especially focusing on the effects of LV geometric patterns. METHODS:This was a single-center ...

journal_title：Journal of nephrology

authors： Moon SJ,Bae KS,Park HC,Kim JK,Park JT,Lee JE,Rim SJ,Ha SK

更新日期：2011-01-01 00:00:00

abstract：:Chyluria results from an abnormal connection between lymphatic bed and urinary tract, causing lymph leakage into the urine. The clinical picture often begins with the appearance of cloudy, milky urines accompanied by monolateral flank pain, malnutrition, weight loss and weakness. We report a case of chyluria that occu...

journal_title：Journal of nephrology

authors： Graziani G,Cucchiari D,Verdesca S,Balzarini L,Montanelli A,Ponticelli C

更新日期：2011-09-01 00:00:00

abstract：:The management of rapidly progressive glomerulonephritis has been transformed over the past thirty years. It has become one of the few forms of glomerulonephritis that can be effectively treated, and today overall renal survival is as high as 70%. Effective management of patients with RPGN requires prompt and accurate...

journal_title：Journal of nephrology

authors： Erwig LP,Rees AJ

更新日期：1999-07-01 00:00:00

abstract：:The proximal tubule reabsorbs approximately 80% of the filtered load of bicarbonate. Defects in the process of bicarbonate reabsorption result in loss of bicarbonate and proximal renal tubular acidosis. Global proximal tubule dysfunction is known as the Fanconi's syndrome. Both isolated proximal renal tubular acidosis...

journal_title：Journal of nephrology

authors： Quigley R

更新日期：2006-03-01 00:00:00