Disseminated histoplasmosis in acquired immunodeficiency syndrome patients in Uberaba, MG, Brazil.

Abstract:

:Histoplasmosis occurs in approximately 5% of acquired immunodeficiency syndrome (AIDS) patients in endemic areas and often evolves to a disseminated picture if diagnosis is delayed and/or CD4 count falls below 150 cells x mm(3) without high active antiretroviral therapy (HAART). This report presents clinical features of patients with histoplasmosis admitted from 1992 to 2005. Of the 57 individuals, 45 (79%) were male, aged 20-40 years; 30 (52.6%) presented histoplasmosis together with HIV diagnosis and 35 (61.4%) referred illness course up to 4 weeks. Fever, hepatomegaly and/or splenomegaly, dyspnea and skin lesions were noticed in 50 (87.7%), 38 (66.7%), 30 (52.6%) and 25 (43.9%) patients respectively. High levels of lactic acid dehydrogenase, X-ray lung interstitial pattern, pancytopenia and CD4 count <100 cells x mm(3) were observed in 48 (84.2%), 35 (66%), 34 (59.6%) and 33 (94%) patients respectively. Mycological diagnosis was performed by one or more methods in all patients. Thirty nine (68.4%) received amphotericin B and/or itraconazole. A cure rate was observed in 76.9% and nine (23.1%) died early during therapy. Otherwise death occurred in 18 (31.6%) before diagnosis was completed. Despite free HAART disposal in public Brazilian health services, histoplasmosis still occurs as the first AIDS baseline condition in patients without antiretroviral therapy, many of whom are not receiving any medical care for HIV infection.

journal_name

Mycoses

journal_title

Mycoses

authors

Mora DJ,dos Santos CT,Silva-Vergara ML

doi

10.1111/j.1439-0507.2007.01459.x

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

136-40

issue

2

eissn

0933-7407

issn

1439-0507

pii

MYC1459

journal_volume

51

pub_type

杂志文章

相关文献

MYCOSES文献大全
  • Extracellular protease expression in Microsporum gypseum complex, its regulation and keratinolytic potential.

    abstract::Two soil isolates of Microsporum gypseum were studied for the production of extracellular proteases. Both the strains secreted protease on glucose-gelatin medium. The enzyme activity peaked on day 15 at 28 °C. Asparagine repressed protease yield. Sugars caused catabolite repression of protease formation. Protease acti...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2010.01871.x

    authors: Singh CJ

    更新日期:2011-07-01 00:00:00

  • [Orointestinal candidiasis with special emphasis on esophageal candidiasis].

    abstract::Orointestinal mycoses are localized mainly in the oral cavity and in the oesophagus. Candida oesophagitis is not only found in AIDS-patients, also in patients of risk admitted to intensive care units. Upper intestinoscopies were made in 124 patients. Oesophageal candidosis was found in 6 patients, two of them had also...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1999.tb04531.x

    authors: Bernhardt J

    更新日期:1999-01-01 00:00:00

  • A rescue therapy with a combination of caspofungin and liposomal amphotericin B or voriconazole in children with haematological malignancy and refractory invasive fungal infections.

    abstract::Combination treatment of paediatric invasive fungal infections (IFIs) has rarely been reported. A total of 17 children with 19 IFI episodes were enrolled in the study. The median age of the patients was 5.3 (range 0.5-17) years. IFI was classified as proven in 4, probable in 12 and possible in 3 episodes. These patien...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2009.01808.x

    authors: Yilmaz D,Balkan C,Ay Y,Akin M,Karapinar B,Kavakli K

    更新日期:2011-05-01 00:00:00

  • In vitro activities of 15 antifungal drugs against a large collection of clinical isolates of Microsporum canis.

    abstract:BACKGROUND:Microsporum canis is a zoophilic species, found to be the most frequently isolated species in animals. M. canis causes sporadic outbreaks of infections in humans, such as the one that occurred in Canada, where more than 1000 human cases were detected over an 8-year period. Despite the medical importance of M...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12986

    authors: Abastabar M,Jedi A,Guillot J,Ilkit M,Eidi S,Hedayati MT,Shokohi T,Daie Ghazvini R,Rezaei-Matehkolaei A,Katiraee F,Javidnia J,Ahmadi B,Badali H

    更新日期:2019-11-01 00:00:00

  • Isolation of Cryptococcus neoformans from pigeon (Columba livia) droppings in Mexico City.

    abstract::To determine the ecological and epidemiological significance of pigeon excrement in cryptococcosis in Mexico City, 251 samples of pigeon droppings were studied. These were collected from houses, public buildings, churches, parks and pigeon nests. Each sample was suspended 1:10 in isotonic saline solution and then cult...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.1994.37.9-10.325

    authors: Castanón-Olivares LR,López-Martínez R

    更新日期:1994-09-01 00:00:00

  • Epidemiology of Aspergillus species causing keratitis in Mexico.

    abstract:BACKGROUND:The incidence of fungal keratitis has increased in recent years. While the epidemiology and clinical roles of various Candida and Fusarium species have been relatively well-identified in infections of the eye, data regarding keratitis caused by Aspergillus species are scant. Accurate and rapid diagnosis is i...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12855

    authors: Al-Hatmi AMS,Castro MA,de Hoog GS,Badali H,Alvarado VF,Verweij PE,Meis JF,Zago VV

    更新日期:2019-02-01 00:00:00

  • [Controversies in the standardization of susceptibility testing on yeasts to azole antimycotics].

    abstract::Due to the different physical-chemical conditions of the therapeutical azoles it is necessary to choose an adequate testing procedure. In the group of azoles caused by its hydrophilia fluconazole susceptibility testing can be handled easily. However it is not possible to take the same test conditions for itraconazole ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1996.tb00523.x

    authors: Tintelnot K,Seibold M

    更新日期:1996-01-01 00:00:00

  • [Fusarium in dermatology].

    abstract::The relevance of infections with moulds in humans is increasing. Relevant genera are Alternaria, Cladosporium, Scopulariopsis, and Fusarium. Fusarium thereby is characterized by typical makroconidia and special makroscopical features. Known as pathogen in plants the fungi can also cause intoxications and - more seldom...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.2009.01837.x

    authors: Seyfarth F,Hipler UC

    更新日期:2010-05-01 00:00:00

  • Ecthyma-like phaeohyphomycosis caused by Cladosporium cladosporioides.

    abstract::A case of cutaneous phaeohyphomycosis caused by Cladosporium cladosporioides in a 50-year-old housewife is described. The clinical presentation was an ecthyma-like crusted lesion on the back of her left hand. Scanning electron microscopy of the culture showed the conidiophores and the limoniform or ellipsoidal conidia...

    journal_title:Mycoses

    pub_type: 信件

    doi:10.1111/j.1439-0507.2009.01745.x

    authors: Duquia RP,de Almeida HL Jr,Vettorato G,Rocha NM,de Castro LA

    更新日期:2010-11-01 00:00:00

  • Comparative studies on the detection of antibodies and delayed hypersensitivity responses with 10 Blastomyces dermatitidis lysate antigens.

    abstract::Yeast-phase lysate antigens were prepared from 10 different isolates of Blastomyces dermatitidis. Comparative studies were performed using the lysate antigens in an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies in sera from dogs with blastomycosis and histoplasmosis. In order to evaluate th...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1997.tb00206.x

    authors: Wakamoto A,Abuodeh RO,Scalarone GM

    更新日期:1997-10-01 00:00:00

  • Preanalytical conditions for broth microdilution antifungal susceptibility of Microsporum spp.

    abstract::Dermatophytoses caused by the genus Microsporum require a long-duration therapy compared to infections caused by other genera. Treatment of these cutaneous infections includes topical and systemic antifungal agents. Tinea capitis and tinea unguium caused by M. canis and M. gypseum are the most difficult-to-treat derma...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2008.01503.x

    authors: Biancalana FS,Telles PF,Lyra L,Schreiber AZ

    更新日期:2008-07-01 00:00:00

  • Effects of repeated low-dose UVB irradiation on the hyphal growth of Candida albicans.

    abstract::Ultraviolet B light (UVB) can have negative phototropic effects on fungi. Candida albicans is often found on human skin exposed to UVB. Therefore, it is of medical interest to know whether a negative phototropic response to UVB irradiation can support an invasive growth of this potentially dangerous agent. In our stud...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2005.01169.x

    authors: Brasch J,Kay C

    更新日期:2006-01-01 00:00:00

  • Determination of antidermatophytic effects of non-steroidal anti-inflammatory drugs on Trichophyton mentagrophytes and Epidermophyton floccosum.

    abstract::Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most common pharmacological agents. They have three primary therapeutic properties including anti-inflammatory, anti-pyretic and analgesic effects. Seven NSAIDs were tested against two species of dermatophytes. Percentage inhibition was determined for effec...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2010.01945.x

    authors: Al-Janabi AA

    更新日期:2011-09-01 00:00:00

  • Molecular detection and characterisation of fungal heat shock protein 60.

    abstract::Heat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up-regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties. A possible cellular heat shock response was inves...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2010.01933.x

    authors: Raggam RB,Salzer HJ,Marth E,Heiling B,Paulitsch AH,Buzina W

    更新日期:2011-09-01 00:00:00

  • Oral clioquinol is effective in the treatment of a fly model of Candida systemic infection.

    abstract:BACKGROUND:Clioquinol was used in the 1950s-1970s as antimicrobial but its oral formulations were withdrawn from the market due to suspected neurotoxicity. Currently, there is possibility of repositioning of oral clioquinol formulations. OBJECTIVES:To evaluate the antifungal activity and toxicological parameters of cl...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12888

    authors: Pippi B,Merkel S,Staudt KJ,Teixeira ML,de Araújo BV,Zanette RA,Andrade SF,Fuentefria AM

    更新日期:2019-05-01 00:00:00

  • Clinical mycology in Latin America and the Caribbean: A snapshot of diagnostic and therapeutic capabilities.

    abstract::Despite the existence of endemic mycoses in Latin America and the Caribbean, in addition to a large population of patients at risk for invasive mycoses, the capability of medical centres to perform a proper diagnosis in mycology has not been studied in the region. Moreover, availability of antifungal drugs in the regi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12890

    authors: Falci DR,Pasqualotto AC

    更新日期:2019-04-01 00:00:00

  • [Antimicrobial prophylaxis and therapy in neutropenia].

    abstract::Cytostatic chemotherapy of hematological malignancies if often complicated by neutropenia, which increases the risk of infections, especially if the neutrophil count is below 500/ml. Frequently, fever is the first and in most patients the only sign of an infection. Unexplained fever is defined as follows: temperature ...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:

    authors: Link H

    更新日期:2003-01-01 00:00:00

  • Case report. Cutaneous cryptococcosis in a patient with systemic erythematous lupus.

    abstract::The first case of a cutaneous cryptococcosis associated with systemic erythematous lupus (SLE) diagnosed in our Mycology Reference Centre is presented: a 24-year-old female patient diagnosed with SLE, nephrotic syndrome, arterial hypertension, renal insufficiency due to glomerulonephritis type IV and cellulitis in the...

    journal_title:Mycoses

    pub_type: 信件

    doi:10.1046/j.1439-0507.2001.00661.x

    authors: Ramos L,López C,Gómez C,Mathurín S,Mateo A

    更新日期:2001-11-01 00:00:00

  • Case report. Monascus purpureus--a new fungus of allergologic relevance.

    abstract::Anaphylactic reactions to food containing allergens in the consumption or preparation of food are well known. However, allergy in the preparation of sausages has rarely been described. In the present study a 26-year-old-butcher was investigated who had a severe anaphylactic reaction developing sneezing, rhinitis, conj...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:

    authors: Hipler UC,Wigger-Alberti W,Bauer A,Elsner P

    更新日期:2002-02-01 00:00:00

  • Inhibitory effect of nicotinamide on enzymatic activity of selected fungal strains causing skin infection.

    abstract::Pathogenicity of fungi is connected with their ability to easily penetrate the host tissues, survive in the infected host organism and use the elements of the host tissues as nutrients. Hence, the co-occurrence of pathogenic properties with the high enzymatic activity, which is manifested through the production of var...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2009.01696.x

    authors: Ciebiada-Adamiec A,Małafiej E,Ciebiada I

    更新日期:2010-05-01 00:00:00

  • Clinical characteristics, rapid identification, molecular epidemiology and antifungal susceptibilities of Talaromyces marneffei infections in Shenzhen, China.

    abstract::Although case series of talaromycosis have been reported in China, their detailed clinical and microbiological characteristics have never been systematically profiled. In this study, we report the clinical characteristics, molecular epidemiology, rapid identification and antifungal susceptibilities of talaromycosis in...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12887

    authors: Lau SKP,Xing F,Tsang CC,Tang JYM,Tan YP,Ye H,Lau RWT,Chen JHK,Lo SKF,Woo PCY

    更新日期:2019-05-01 00:00:00

  • Identification of Microsporum canis from dermatophytic pseudomycetoma in paraffin-embedded veterinary specimens using a common PCR protocol.

    abstract::The effectiveness of a simple PCR protocol performed on paraffin-embedded tissues, obtained from histopathologically and culturally diagnosed cases of dermatophytic pseudomycetoma DPM was tested. The specimens were investigated using previously described primers (DH1L and DH1R) targeting the 18S rDNA gene and amplifyi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2007.01368.x

    authors: Nardoni S,Franceschi A,Mancianti F

    更新日期:2007-05-01 00:00:00

  • Mixed intranasal infection caused by Fusarium solani and a zygomycete in a leukaemic patient.

    abstract::We report a case of mixed intranasal infection caused by Fusarium solani and a zygomycete, with probable sinus and brain involvement. The patient had chronic myelogenous leukaemia and was treated with chemotherapy. Diagnosis of the infection was established by direct examination of the intranasal eschar and histopatho...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.1995.tb00408.x

    authors: Lopes JO,de Mello ES,Klock C

    更新日期:1995-07-01 00:00:00

  • [Molecular biological methods and their consequences in taxonomy and diagnosis of dermatophytes].

    abstract::Trichophyton rubrum, T. mentagrophytes, T. verrucosum, Microsporum canis, M. gypseum and Epidermophyton flocoosum represent the cause of human dermatomycoses isolated most often at the University Hospital of Dermatology in Graz, Austria, between 1991 and 1998. So far, identification was mainly based on the cultivation...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:

    authors: Blanz P,Buzina W,Ginter G,Gräser Y

    更新日期:2000-01-01 00:00:00

  • First isolation of Candida wangnamkhiaoensis from the blood of immunocompromised paediatric patient.

    abstract::Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C. wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name a...

    journal_title:Mycoses

    pub_type:

    doi:10.1111/myc.12509

    authors: Tap RM,Ho Betty LS,Ramli NY,Suppiah J,Hashim R,Sabaratnam P,Ginsapu SJ,Gowbei A,Razak MF,Sipiczki M,Ahmad N

    更新日期:2016-11-01 00:00:00

  • The aetiological agents of superficial cutaneous mycoses in Jos, Plateau State of Nigeria.

    abstract::A survey of superficial skin mycoses was carried out among miners and office workers employed in different establishments in Jos, Nigeria. Mycotic infection was demonstrable by microscopy and culture in 45 (10.4%) subjects: 20 males and 25 females. Malassezia furfur was the predominant aetiological agent, followed by ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1995.tb00058.x

    authors: Ayanbimpe GH,Bello CS,Gugnani HC

    更新日期:1995-05-01 00:00:00

  • An evaluation of seven methods of testing in vitro susceptibility of clinical yeast isolates to fluconazole.

    abstract::Four commercially available in vitro test systems (Candifast, E-test, Mycototal and spiral-gradient end point method), agar diffusion with 25-micrograms fluconazole paper test discs and 15-micrograms test tablets and agar dilution were compared with the microbroth dilution method for fluconazole susceptibility testing...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1995.tb00065.x

    authors: Schmalreck AF,Kottmann I,Reiser A,Ruffer U,Scharr E,Vanca E

    更新日期:1995-09-01 00:00:00

  • [Therapy of intraabdominal fungal infections].

    abstract::Candida albicans is the fourth most germ that can be identified on surgical intensive care unit (SICU). During the course of severe peritonitis recognition of Candida is crucial for physicians but interpretation of Candida-positive microbiologic samples is difficult. The indication for antimycotic therapy requires dif...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.2005.01115.x

    authors: Kujath P,Bouchard R,Nolde J,Scheele J

    更新日期:2005-01-01 00:00:00

  • Burden of serious fungal infections in Belgium.

    abstract::We aimed to estimate the total number of serious fungal infections occurring yearly in Belgium. The number of cryptococcal infections was retrieved from the National Reference Center for Mycosis. Populations at risk and fungal infections frequencies in these populations were used to estimate incidence or prevalence of...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12389

    authors: Lagrou K,Maertens J,Van Even E,Denning DW

    更新日期:2015-10-01 00:00:00

  • Antifungal combinations in Mucorales: A microbiological perspective.

    abstract::Mucormycosis mostly affects immunocompromised patients and is associated with a high morbidity and mortality despite currently available treatments. In that context, combination therapy might be the key to a better outcome for these patients. Purpose of this review is to summarise and to discuss the current combinatio...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12909

    authors: Schwarz P,Cornely OA,Dannaoui E

    更新日期:2019-09-01 00:00:00