Doxazosin in the treatment of mild or moderate essential hypertension: an echocardiographic study.

abstract：:In 10 treated and 2 control dogs, the short-term effects of intravenous propafenone (2 mg/kg/10 minutes, followed by 1 mg/min [n = 2] or 25 micrograms/kg/min [n = 8]) on the internal ventricular defibrillation energy requirements (DER) were investigated. Multiple stored energy levels were randomly tested and the perce...

journal_title：American heart journal

authors： Peters W,Gang ES,Okazaki H,Solingen S,Kobayashi Y,Karagueuzian HS,Mandel WJ

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine in pediatric Duchenne (DMD) and Becker muscular dystrophy (BMD) or other dilated cardiomyopathies (ODCM) whether outcomes differ by diagnosis. BACKGROUND:Children with dilated cardiomyopathy are treated as a single undifferentiated group. METHODS:This cohort study of 1...

journal_title：American heart journal

authors： Connuck DM,Sleeper LA,Colan SD,Cox GF,Towbin JA,Lowe AM,Wilkinson JD,Orav EJ,Cuniberti L,Salbert BA,Lipshultz SE,Pediatric Cardiomyopathy Registry Study Group.

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Although age is the most important variable associated with death among patients with persistent ST-segment elevation, its impact on outcome among patients without persistent ST-segment elevation remains unknown. Moreover, the impact of age on the efficacy of antiplatelet therapy with eptifibatide is unknown...

journal_title：American heart journal

authors： Hasdai D,Holmes DR Jr,Criger DA,Topol EJ,Califf RM,Harrington RA

更新日期：2000-05-01 00:00:00

abstract：:A new radiopaque, highly flexible balloon-expandable tantalum stent was tested. Thirty-six of 40 stents were successfully deployed percutaneously in the coronary arteries of 31 dogs. The dogs were given aspirin before, intravenous heparin during, and aspirin alone after the procedure. One dog died at 24 hours because ...

journal_title：American heart journal

authors： Muhlestein JB,Phillips HR,Quigley PJ,Bauman RP,Gammon RS,Chapman GD,Mikat EM,Palmos LE,Overman AB,Stack RS

更新日期：1992-10-01 00:00:00

abstract：:This study was designed to evaluate the relative diagnostic values of transthoracic (TTE) and transesophageal (TEE) echocardiography in the assessment of congenitally corrected transposition of the great arteries in adult patients. Twelve patients (mean age 29 years, range 21 to 39 years) with congenitally corrected t...

journal_title：American heart journal

authors： Caso P,Ascione L,Lange A,Palka P,Mininni N,Sutherland GR

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:According to a recent meta-analysis, parathyroid hormone (PTH) excess is associated with increased cardiovascular disease (CVD) risk, but existing studies are limited. We examined in a prospective study the association of PTH with the incidence of CVD, taking into account vitamin D and other confounding vari...

journal_title：American heart journal

authors： Folsom AR,Alonso A,Misialek JR,Michos ED,Selvin E,Eckfeldt JH,Coresh J,Pankow JS,Lutsey PL

更新日期：2014-09-01 00:00:00

abstract：:Reperfusion therapy has lowered the mortality in patients suffering acute myocardial infarction. Failure to reperfuse is associated with significantly higher risk of short- and long-term mortality. Detection of reperfusion is thus important. In a prospective pilot study, we used continuous on-line computerized vectorc...

journal_title：American heart journal

authors： Dellborg M,Topol EJ,Swedberg K

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:In patients with acute myocardial infarction (AMI), depressive symptoms increase the risk for cardiac events. Recently, the S allele of the serotonin transporter (5-HTT) gene-linked polymorphic region was shown to reduce transcription of this gene and thus reduce serotonin reuptake, and this allele is linked...

journal_title：American heart journal

authors： Nakatani D,Sato H,Sakata Y,Shiotani I,Kinjo K,Mizuno H,Shimizu M,Ito H,Koretsune Y,Hirayama A,Hori M,Osaka Acute Coronary Insufficiency Study Group.

更新日期：2005-10-01 00:00:00

abstract：:Bacterial shock due to Gram-negative bacilli is best managed by prompt control of the infection with appropriate antibiotics and surgical drainage or excision. Corticosteroids for purposes of controlling systemic reactions to bacteria and their toxins constitute adjunctive therapy. Volume repletion and respiratory sup...

journal_title：American heart journal

authors： Shubin H,Weil MH,Carlson RW

更新日期：1977-07-01 00:00:00

abstract：AIM:The aim of the study was to assess and compare the safety of antiarrhythmic drugs (AADs) in an unselected real-world population of patients with atrial fibrillation (AF). METHODS AND RESULTS:This is a study of all patients with diagnosed AF in the Swedish Patient register who filled a prescription for sotalol, ami...

journal_title：American heart journal

authors： Friberg L

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Conflicting data exist regarding a potential deleterious association between aspirin (ASA) and angiotensin-converting enzyme inhibitors (ACEIs) when used concurrently in patients with heart failure (HF). How such an interaction may be influenced by underlying etiology of HF and whether it extends to patients...

journal_title：American heart journal

authors： Levy PD,Nandyal D,Welch RD,Sun JL,Pieper K,Ghali JK,Fonarow GC,Gheorghiade M,O'Connor CM

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Adenosine cardiac stress is widely used as an alternative to exercise testing during myocardial perfusion imaging (MPI). Dyspnea often accompanies the adenosine stress test. Although known asthmatic patients are excluded from this test because of the danger of bronchospasm, there is incomplete information re...

journal_title：American heart journal

authors： Balan KK,Critchley M

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The effect of raloxifene on aortic elasticity in healthy postmenopausal women is unknown. The purpose of the present study was to examine the effect of raloxifene on aortic elasticity and cardiovascular structure and function in healthy postmenopausal women. METHODS:A randomized, crossover, double-blind, pl...

journal_title：American heart journal

authors： Tritos NA,Goepfert L,Kissinger KV,Katsimaglis G,Manning WJ,Danias PG

更新日期：2005-12-01 00:00:00

abstract：:The antiarrhythmic efficacy and safety of intravenous amiodarone were evaluated in 13 patients with recurrent sustained ventricular tachycardia. All patients had been refractory to at least three prior antiarrhythmic agents (mean, 3.3 per patient), and 11 had multiple direct current cardioversions. Intravenous amiodar...

journal_title：American heart journal

authors： Klein RC,Machell C,Rushforth N,Standefur J

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Many young investigators are interested in cardiovascular (CV) outcomes research; however, the current training experience of early investigators across the United States is uncertain. METHODS:From April to November 2014, we surveyed mentees and mentors of early-stage CV outcomes investigators across the Un...

journal_title：American heart journal

authors： Khazanie P,Al-Khatib SM,Wang TY,Crowley MJ,Kressin NR,Krumholz HM,Kiefe CI,Wells BL,O'Brien SM,Peterson ED,Sanders GD

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The pathogenesis of human coronary artery disease (CAD) is likely to require the transcription of many different genes. We report here the differential gene expression profiling of human CAD using copy DNA (cDNA)/nylon array hybridization techniques. METHODS AND RESULTS:Human coronary arteries...

journal_title：American heart journal

authors： Satterthwaite G,Francis SE,Suvarna K,Blakemore S,Ward C,Wallace D,Braddock M,Crossman D

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:The objective of the study was to test the hypothesis that intracellular calcium modulation by 5-methyl-2-[piperazin-1-yl] benzene sulfonic acid monohydrate (MCC-135 [Caldaret]; Mitsubishi Pharma Corporation, Osaka, Japan) would preserve left ventricular function and reduce infarct size in patients undergoin...

journal_title：American heart journal

authors： Jang IK,Weissman NJ,Picard MH,Zile MR,Pettigrew V,Shen S,Tatsuno J,Hibberd MG,Tzivoni D,Wackers FJ,EVOLVE Investigators.

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Although quantification of the impact of treatment on survival remains the cornerstone of clinical research, the assessment of a broader range of disease outcomes is growing increasingly important. This manuscript provides an overview of the considerations made regarding quantification of a range of clinical...

journal_title：American heart journal

authors： Spertus JA,Tooley J,Jones P,Poston C,Mahoney E,Deedwania P,Hurley S,Pitt B,Weintraub WS

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Single center studies using serial cerebral diffusion-weighted magnetic resonance imaging in patients having cardiac catheterization have suggested that cerebral microembolism might be responsible for silent cerebral infarct (SCI) as high as 15% to 22%. We evaluated in a multicenter trial the incidence of SC...

journal_title：American heart journal

authors： Hamon M,Lipiecki J,Carrié D,Burzotta F,Durel N,Coutance G,Boudou N,Colosimo C,Trani C,Dumonteil N,Morello R,Viader F,Claise B,Hamon M

更新日期：2012-10-01 00:00:00

abstract：:The calcium antagonist, manidipine, was developed on the basis of the hypothesis that antihypertensive drugs that act to improve renal hemodynamic alterations will be therapeutically beneficial in hypertensive patients. Manidipine shows long-lasting calcium channel-blocking action in vascular smooth muscle cells and a...

journal_title：American heart journal

authors： Nagaoka A

更新日期：1993-02-01 00:00:00

abstract：:Although successful dilatation of a target lesion by means of percutaneous transluminal coronary angioplasty (PTCA) can be attained as frequently in elderly as in younger patients, elderly patients have a higher risk of complications. Furthermore, cohorts of patients older than 75 years and undergoing PTCA include mor...

journal_title：American heart journal

authors： Lindsay J Jr,Reddy VM,Pinnow EE,Little T,Pichard AD

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Sexuality is an important factor influencing quality of life that may be altered for patients with coronary disease. Little is known about the extent to which patients want their cardiologists to counsel them about sexuality. PURPOSE:Our study evaluated the extent to which patients with known coronary disea...

journal_title：American heart journal

authors： Bedell SE,Duperval M,Goldberg R

更新日期：2002-08-01 00:00:00

abstract：:Abnormal interventricular septal motion is a frequent finding after cardiac surgery. However, the time course and underlying mechanisms are not well understood. Nineteen patients, mean age 54 years (range 20 to 82 years), were studied with intraoperative transesophageal echocardiography at five specific times: with th...

journal_title：American heart journal

authors： Wranne B,Pinto FJ,Siegel LC,Miller DC,Schnittger I

更新日期：1993-07-01 00:00:00

abstract：:Valve area and cardiac output were determined with magnetic resonance (MR) velocity mapping in 12 patients with aortic stenosis. Heart catheterization, Doppler echocardiography, and indicator dilution were performed for comparison. Left ventricle could be catheterized in only nine patients; in these cases, MR measured...

journal_title：American heart journal

authors： Søndergaard L,Hildebrandt P,Lindvig K,Thomsen C,Ståhlberg F,Kassis E,Henriksen O

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Nitroglycerin is known to augment vessel wall squeezing at the site with coronary-myocardial bridging (CMB). This study was designed to define the mechanism of nitroglycerin-induced augmentation of CMB in clinical settings. METHODS:We analyzed nitroglycerin reactivity at the site with CMB in 39 patients. Ma...

journal_title：American heart journal

authors： Hongo Y,Tada H,Ito K,Yasumura Y,Miyatake K,Yamagishi M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The CD40 receptor and its ligand (CD40L) are known to modulate both inflammation and thrombosis-2 processes important for the development and clinical expression of atherosclerosis. Circulating soluble CD40L (sCD40L) concentration predicts cardiovascular risk in selected patient samples. The purpose of this ...

journal_title：American heart journal

authors： Keaney JF Jr,Lipinska I,Larson MG,Dupuis J,Freedman JE,Hamburg NM,Massaro JM,Rong J,Sutherland P,Vita JA,Vasan RS,Benjamin EJ

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Rheumatic disease and heart disease share common underpinnings involving inflammation. The high levels of inflammation that characterize rheumatic diseases provide a "natural experiment" to help elucidate the mechanisms by which inflammation accelerates heart disease. Rheumatoid arthritis (RA) is the most co...

journal_title：American heart journal

authors： Crowson CS,Liao KP,Davis JM 3rd,Solomon DH,Matteson EL,Knutson KL,Hlatky MA,Gabriel SE

更新日期：2013-10-01 00:00:00

abstract：:Economic assessment can be incorporated into clinical trials to evaluate and compare the costs and benefits of different health care programs. In this article the three main types of evaluation are discussed: cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis. The measurement of direct and i...

journal_title：American heart journal

authors： Bulpitt CJ,Fletcher AE

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Although more than one million patients in the United States have permanent pacemakers, little is known about their cause of death. We evaluated the cause of death in 404 patients who died in the Mode Selection Trial (MOST). METHODS:In MOST, patients received a dual-chamber pacemaker randomly programmed to ...

journal_title：American heart journal

authors： Flaker G,Greenspon A,Tardiff B,Schron E,Goldman L,Hellkamp A,Lee K,Lamas G,Mode Selection Trial (MOST) Investigators.

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Peripheral endothelial dysfunction (ED) quantified by the determination of flow-mediated dilation (FMD%) of the brachial artery with the use of high-resolution ultrasound is an early marker of atherosclerosis. Although a positive correlation with coronary artery disease (CAD) has been reported, the unanswere...

journal_title：American heart journal

authors： Schroeder S,Enderle MD,Ossen R,Meisner C,Baumbach A,Pfohl M,Herdeg C,Oberhoff M,Haering HU,Karsch KR

更新日期：1999-10-01 00:00:00