Abstract:
AIMS:We examined the left lateral ridge (LLR) between the orifices of the left pulmonary veins and the left atrial appendage for a better understanding of its structural composition relevant to ablations for atrial fibrillation (AF). METHODS AND RESULTS:The LLR and its surrounding areas were studied in 40 heart specimens by dissection and histological sections. The LLR is a fold of the atrial wall with a mean width that was narrower superiorly than inferiorly (P < 0.001). Its myocardial thickness at the antero-superior level was thicker than at the postero-inferior level (2.8 +/- 1.1 vs. 1.7 +/- 0.8 mm, P < 0.001). Transmurally from subepicardium to subendocardium, the LLR comprises myofibres from the leftward extension of Bachmann's bundle together with the inferior branches of the septopulmonary bundle and the septoatrial bundle. The vein or ligament of Marshall is located on the epicardial aspect of the LLR. The Marshall structures and autonomic nervous system are in close proximity (<3 mm) to the endocardial surface at the superior level of the ridge in 70% of specimens. CONCLUSION:The variability in width and thickness of the LLR, its proximity to Marshall structures and autonomic nerves, and myofibre arrangement may be significant in the fibrillatory process and spread of AF activity.
journal_name
Eur Heart Jjournal_title
European heart journalauthors
Cabrera JA,Ho SY,Climent V,Sánchez-Quintana Ddoi
10.1093/eurheartj/ehm606subject
Has Abstractpub_date
2008-02-01 00:00:00pages
356-62issue
3eissn
0195-668Xissn
1522-9645pii
29/3/356journal_volume
29pub_type
杂志文章abstract::From 1978 to 1980, 260 healthy subjects, 40-79 years of age, underwent 24 h ambulatory electrocardiography in order to determine the prevalence and complexity of ventricular premature beats (VPBs) in adults without apparent heart disease. The number of types of VPBs seem in 5% or less were considered 'abnormal' and th...
journal_title:European heart journal
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journal_title:European heart journal
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journal_title:European heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:European heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:European heart journal
pub_type: 杂志文章,评审
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更新日期:2012-05-01 00:00:00
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pub_type: 杂志文章
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