Severe and steroid-resistant Crohn's disease.

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) is a standard treatment for tumors of the gastrointestinal tract. We developed a self-completion method of ESD using Endosaber to eliminate the need for an additional device or human assistance during the procedure. The aim of this study was to evaluate the technical fe...

journal_title：Digestion

authors： Esaki M,Minoda Y,Wada M,Sakisaka S,Tsuruta S,Hosokawa T,Matsuguchi T,Ichijima R,Suzuki S,Tamura Y,Iwao A,Yamakawa S,Irie A,Ihara E,Ogawa Y

更新日期：2019-09-27 00:00:00

abstract：:Intestinal absorption after extensive small bowel resections, for diseases other than Crohn's disease, was studied in 17 patients. When the ileocecal valve and the right colon were preserved, malabsorption was transient and moderate and had no prejudicial nutritional effect (fecal fat: 8.8 +/- 1.8 g/24 h in resections...

journal_title：Digestion

authors： Cosnes J,Gendre JP,Le Quintrec Y

更新日期：1978-01-01 00:00:00

abstract：:Natural motilin was investigated for its effect on gastrointestinal motor activity in anesthetized dogs. In doses starting from 10 ng/kg as single injection and 100 ng/kg-h as intravenous infusion, motilin induced phasic pressure changes in the lower esophageal sphincter (LES) and in the lumen of the fundus, antrum, a...

journal_title：Digestion

authors： Jennewein HM,Hummelt H,Siewert R,Waldeck F

更新日期：1975-01-01 00:00:00

abstract：:We previously reported that numerous macrophages which phagocytosed dextran sulfate sodium were observed to have accumulated in the mucosal lesions and in the spleen in experimental ulcerative colitis induced in mice with dextran sulfate sodium. In this paper, we investigated the bacterial phagocytic ability of macrop...

journal_title：Digestion

authors： Ohkusa T,Okayasu I,Tokoi S,Araki A,Ozaki Y

更新日期：1995-01-01 00:00:00

abstract：AIMS:To evaluate the prevalence of proximal reflux and esophago-bronchial reflex (EBR) in patients with asthma, and to compare the symptom spectrum, esophageal acid sensitivity, pH monitoring, and the endoscopic and manometric parameters of EBR-positive and -negative patients with asthma. PATIENTS AND METHODS:Forty-th...

journal_title：Digestion

authors： Rosztóczy A,Makk L,Izbéki F,Róka R,Somfay A,Wittmann T

更新日期：2008-01-01 00:00:00

abstract：:A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：:This study examined the morphological and functional adaptations occurring in the jejunum of adult rats fed totally by parenteral nutrition during a 4-day period. Comparison was made with sham-operated animals receiving orally a similar isocaloric diet. The intravenously fed rats exhibited a 20% shortening of the vill...

journal_title：Digestion

authors： Raul F,Galluser M,Doffoel M

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...

journal_title：Digestion

authors： Wen J,Liu Q,Song J,Tong M,Peng L,Liang H

更新日期：2013-01-01 00:00:00

abstract：:Differential absorption of D-xylose and 3-O-methyl-D-glucose, and unmediated intestinal permeation of lactulose and L-rhamnose has been investigated in 14 patients with diarrhoea following tropical exposure and in 16 healthy control subjects. Five had malabsorption of fat, D-xylose and B12 ('tropical malabsorption' (T...

journal_title：Digestion

authors： Cook GC,Menzies IS

更新日期：1986-01-01 00:00:00

abstract：:Different materials dissolved in 0.9% NaCl were injected into the connective, interlobular tissue of the duodenal part of the rat pancreas. Activated rat pancreatic juice or trypsin were able to induce localized necrohemorrhagic pancreatitis. Only mild edema and leukocytic infiltration were observed after injecting bo...

journal_title：Digestion

authors： Odaira C,Berger Z,Iovanna JL,Sarles H

更新日期：1986-01-01 00:00:00

abstract：:In chronic pancreatitis the exocrine pancreatic tissue is replaced by extracellular matrix deposits from fibroblasts. We have stimulated fibrogenesis in the pancreas by inducing a single episode of cerulein pancreatitis (10 microg/kg/h for 12 h). We have used a spectrophotometrical assay to measure the tissue hydroxyp...

journal_title：Digestion

authors： Weidenbach H,Lerch MM,Turi S,Bachem M,Adler G

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...

journal_title：Digestion

authors： Kim SI,Jin YJ,Lee SH,Lee JW,Lee DH,Lee D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:In the human stomach various alcohol dehydrogenase (ADH) isoenzymes exist. The gastric ADH activity is affected by a number of factors including also the infection of Helicobacter pylori. The objective was to investigate the activity of alcohol dehydrogenase isoenzymes of class I, III and IV in endoscop...

journal_title：Digestion

authors： Chrostek L,Jelski W,Szmitkowski M,Laszewicz W

更新日期：2002-01-01 00:00:00

abstract：:CCK-8, bombesin, secretin and urecholine added in various concentrations to the incubation medium of the dispersed pancreatic acini, obtained from rats, resulted in a dose-dependent stimulation of amylase secretion, the half-maximal response being achieved at 3 X 10(-12), 10(-10), 10(-7) and 10(-5) M, respectively. Pi...

journal_title：Digestion

authors： Jaworek J,Konturek SJ

更新日期：1987-01-01 00:00:00

abstract：:The rates of intracellular transport of newly synthesized amylase, lipase, trypsinogen and chymotrypsinogen were compared in the anaesthesized rat pancreas by measuring their rates of secretion while keeping their relative rates of synthesis in a steady state. It is concluded that pancreatic proteins are not transport...

journal_title：Digestion

authors： Iovanna J,Giorgi D,Dagorn JC

更新日期：1986-01-01 00:00:00

abstract：INTRODUCTION:Weakly acidic reflux has been reported to be the major cause of symptoms in patients with proton pump inhibitor (PPI)-refractory nonerosive reflux disease (NERD) undergoing PPI treatment. We previously reported that reflux at pH 4-5 was the main factor that induced symptoms in such patients. The present st...

journal_title：Digestion

authors： Abe Y,Koike T,Saito M,Okata T,Nakagawa K,Hatta W,Asanuma K,Uno K,Asano N,Imatani A,Masamune A

更新日期：2020-02-14 00:00:00

abstract：:Amylase/creatinine clearance ratio (CAm/CCr), urinary protein concentration and urinary protein pattern were studied in 102 samples from 27 patients with acute pancreatitis and in 46 controls. Raised CAm/CCr, proteinuria and a tubular protein pattern were present in 74, 56 and 96% of the patients, respectively. Howeve...

journal_title：Digestion

authors： Lankisch PG,Wolfrum DI,Koop H,Winckler K

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is a functional bowel disorder which is characterized by abdominal pain and disturbed bowel habits. The pathophysiological mechanism is complex and still remains incompletely clear. Alterations at both the central and the peripheral level are thought to contribute to the sympto...

journal_title：Digestion

authors： Zhang H,Yan Y,Shi R,Lin Z,Wang M,Lin L

更新日期：2008-01-01 00:00:00

abstract：:Gastro-oesophageal reflux disease (GORD) is a chronic illness causing recurrent typical and atypical symptoms. Possible complications include oesophagitis, ulcer, stricture and Barrett's oesophagus. Evidence suggests that the intraoesophageal pH correlates directly with the degree of mucosal injury. Proton pump inhibi...

journal_title：Digestion

authors： Savarino V,Dulbecco P

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIM:Studies have demonstrated an important role for endogenous PG and NO in the healing of chronic gastric ulcers. We investigated the effects of COX and NOS inhibitors on the healing of duodenal ulcers, in comparison with gastric ulcers, in rats. METHODS:Gastric and duodenal ulcers were induced by serosal ...

journal_title：Digestion

authors： Araki H,Komoike Y,Matsumoto M,Tanaka A,Takeuchi K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The frequency of benign stenosis in ulcerative colitis (UC) is low, reported as being 3.2-11.2%, with fibrosis in the submucosa or deeper pointed out as one of the causes. The aim of the present study was to assess stenosis in UC cases using immunostaining and to analyze differences between stenotic...

journal_title：Digestion

authors： Yamagata M,Mikami T,Tsuruta T,Yokoyama K,Sada M,Kobayashi K,Katsumata T,Koizumi W,Saigenji K,Okayasu I

更新日期：2011-01-01 00:00:00

abstract：:Non-erosive reflux disease (NERD) has assumed increasing prominence in studies of gastroesophageal reflux disease (GERD), but it remains a challenge to define NERD precisely and to define its place in the investigation and treatment of GERD. Most simply, NERD may be defined as GERD in an individual who has no evidence...

journal_title：Digestion

authors： Armstrong D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:While probiotic bacteria are successfully used in the treatment of ulcerative colitis, the effect of commercially available probiotic products is still controversial. Here, we study whether the number of living probiotic bacteria in yoghurts is altered by an interruption of the cold chain. METHODS:Thre...

journal_title：Digestion

authors： Scharl M,Geisel S,Vavricka SR,Rogler G

更新日期：2011-01-01 00:00:00

abstract：:This study was undertaken to evaluate the effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients. Sixteen cirrhotics were randomly assigned to metoclopramide (10 mg i.v.) or saline. Metoclopramide significantly decreased transmural variceal pressure (15.7% decr...

journal_title：Digestion

authors： Taranto D,Suozzo R,de Sio I,Romano M,Caporaso N,Del Vecchio Blanco C,Coltorti M

更新日期：1990-01-01 00:00:00

abstract：:Somatostatin is widely distributed throughout the human gastrointestinal system. There it is found in neurons and fibers of both the submucosal and the myenteric plexus and the pancreas as well as in the D cells of the stomach, gut and pancreatic islets. Whereas in the intestinal nervous system, in the duodenum and th...

journal_title：Digestion

authors： Gyr KE,Meier R

更新日期：1993-01-01 00:00:00

abstract：:The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diar...

journal_title：Digestion

authors： Burroughs AK,Malagelada R

更新日期：1993-01-01 00:00:00

abstract：:The secretion of pancreatic polypeptide (PP) seems to be controlled by vagal cholinergic mechanisms, since both vagotomy and atropine significantly inhibit the PP response to food intake, sham feeding or insulin hypoglycaemia. In the present study, we examined the PP response to a meal after orthotopic autotransplanta...

journal_title：Digestion

authors： Köhler H,Becker HD

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Although pain is the most feared part of the terminal life of many patients with cancer, the intensity and the quality of the pain is all too often only scantly described. METHOD:The quality and quantity of pain were prospectively registered by five variables, including a visual analogue scale (VAS), in 46 ...

journal_title：Digestion

authors： Grahm AL,Andrén-Sandberg A

更新日期：1997-01-01 00:00:00

abstract：:Net fluid movement and mucosal 14C-erythritol clearance were measured in ligated colonic loops of the rat in vivo. The diphenolic laxatives, oxyphenisatin and bisacodyl, dose-dependently inhibited net fluid absorption or caused secretion, both increased the 14C-erythritol clearance. Pretreatment with the adenylate cyc...

journal_title：Digestion

authors： Farack UM,Nell G

更新日期：1984-01-01 00:00:00

abstract：:The form in which copper is bound in bile was studied in bile from patients with Wilson's disease, control subjects and rats. Bile was labelled with 64Cu. Sephadex column chromatography using gels G-200--G-10 showed a major 64Cu and protein peak of about 5,000 daltons and a minor peak of about 8,000 daltons. A high-mo...

journal_title：Digestion

authors： Frommer DJ

更新日期：1977-01-01 00:00:00