Susceptibility to active decompensated cirrhosis is associated with polymorphisms of intercellular adhesion molecule-1 (ICAM-1) in chronic HBV carriers.

abstract：:In this pilot study, we evaluated the efficacy of interferon-alpha (IFN) plus Thymosin-alpha 1 (TA1) to that of IFN alone in naive patients with chronic hepatitis C. Twenty-two patients were randomized to receive interferon-alpha 2b (3 million units three times a week) plus thymosin-alpha l (900 microg/m2 body surface...

journal_title：Journal of viral hepatitis

authors： Andreone P,Gramenzi A,Cursaro C,Felline F,Loggi E,D'Errico A,Spinosa M,Lorenzini S,Biselli M,Bernardi M

更新日期：2004-01-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a serious cause of liver-related morbidity and mortality. Coexistent infection with HDV tends to aggravate the course of hepatitis B virus (HBV)-associated liver disease. The aim of this study was to determine the prevalence of HDV infection among patients chronically infected with HBV i...

journal_title：Journal of viral hepatitis

authors： Bahcecioglu IH,Aygun C,Gozel N,Poyrazoglu OK,Bulut Y,Yalniz M

更新日期：2011-07-01 00:00:00

abstract：:Quantitative serology for hepatitis B surface antigen (HBsAg) is a new candidate marker for prediction of clinical outcome. The aim of this study was to investigate the clinical significance of quantifying HBsAg in patients with hepatitis B virus (HBV) infection. A total of 424 patients who tested positive for HBsAg a...

journal_title：Journal of viral hepatitis

authors： Togo S,Arai M,Tawada A,Chiba T,Kanda T,Fujiwara K,Imazeki F,Yokosuka O

更新日期：2011-10-01 00:00:00

abstract：:We compared sustained virological response (SVR) in chronic hepatitis C patients with severe fibrosis treated with pegylated interferon (Peg-IFN) alpha-2b 1.5 microg/kg/week or 0.75 microg/kg/week in combination with ribavirin 800 mg/day for 48 weeks. This was a multicentre randomized controlled study. SVR was observe...

journal_title：Journal of viral hepatitis

authors： Abergel A,Hezode C,Leroy V,Barange K,Bronowicki JP,Tran A,Alric L,Castera L,Bernard PH,Henquell C,Lafeuille H,Ughetto S,Darcha C,Chevallier M,Martineau N,Dubost S,Randl K,Dhumeaux D,Bommelaer G,Bonny C,French mult

更新日期：2006-12-01 00:00:00

abstract：:Anaemia during peginterferon (PEG-IFN) and ribavirin (RBV) therapy is common in human immunodeficiency virus/hepatitis C virus (HIV/HCV)-coinfected patients despite the use of lower doses of RBV than are recommended for HIV-seronegative persons. In addition, concurrent zidovudine (ZDV) may exacerbate the anaemia cause...

journal_title：Journal of viral hepatitis

authors： Alvarez D,Dieterich DT,Brau N,Moorehead L,Ball L,Sulkowski MS

更新日期：2006-10-01 00:00:00

abstract：:In Italy, HDV infection endemicity has greatly decreased overtime. Migratory flow may change this scenario as migrants often come from high HDV endemicity areas. Here, we studied characteristics of HDV infection in Italy, particularly addressed to the birth area of subjects. Chronic HBsAg carriers consecutively referr...

journal_title：Journal of viral hepatitis

authors： Stroffolini T,Ciancio A,Furlan C,Vinci M,Fontana R,Russello M,Colloredo G,Morisco F,Coppola N,Babudieri S,Ferrigno L,Sagnelli C,Sagnelli E

更新日期：2020-09-01 00:00:00

abstract：:Socio-demographic and behavioural characteristics are associated with delayed diagnosis and disease progression in HCV-infected persons. However, many analyses focused on single variables rather than groups defined by several variables. We used latent class analysis to study all 4488 persons enrolled in the Swiss Hepa...

journal_title：Journal of viral hepatitis

authors： Giudici F,Bertisch B,Negro F,Stirnimann G,Müllhaupt B,Moradpour D,Cerny A,Keiser O,Swiss Hepatitis C Cohort Study.

更新日期：2016-09-01 00:00:00

abstract：:The aim of this study was to evaluate the Chiron branched DNA (bDNA) assay for detection of serum hepatitis B virus (HBV) DNA in patients with chronic hepatitis B lacking hepatitis B e antigen (HBeAg) and undergoing interferon (IFN) therapy. Results obtained with the bDNA assay were compared with those obtained using ...

journal_title：Journal of viral hepatitis

authors： Habersetzer F,Zoulim F,Jusot JF,Zhang X,Trabaud MA,Chevallier P,Chevallier M,Ahmed SN,Sepetjan M,Comanor L,Minor J,Trépo C

更新日期：1998-11-01 00:00:00

abstract：:Through molecular virological testing it is now clear that HCV reinfection of the allograft is virtually universal in liver transplant recipients. Although histopathological recurrence of hepatitis C occurs in the majority of patients, it is absent in a substantial minority. To date, no prognostic factors, other than ...

journal_title：Journal of viral hepatitis

authors： Vierling JM,Villamil FG,Rojter SE,Camacho KB,Goldman DE

更新日期：1997-01-01 00:00:00

abstract：:Previously, we have determined that human annexin V (hAV), a Ca2+-dependent phospholipid-binding protein, and not rat AV, binds specifically to small hepatitis B surface antigen (SHBsAg), and that transfection of a rat hepatoma cell line with a construct containing the hAV gene led to hAV expression and conferred susc...

journal_title：Journal of viral hepatitis

authors： De Meyer S,Gong ZJ,Hertogs K,Depla E,van Pelt JF,Roskams T,Maertens G,Yap SH

更新日期：2000-03-01 00:00:00

abstract：:A simple, pangenotypic and effective treatment regimen for patients with a broad range of chronic hepatitis C virus (HCV) infections remains an unmet medical need. We conducted a phase 2, randomized, open study involving untreated patients with chronic HCV genotypes 1, 2, 3, or 6 infections. Patients without cirrhosis...

journal_title：Journal of viral hepatitis

authors： Rao H,Song G,Li G,Yang Y,Wu X,Guan Y,Mao Q,Jiang X,Wang C,Zhang Y,Jia J,Guo X,Li C,Ning J,Qin H,Pan H,Wei L

更新日期：2020-01-01 00:00:00

abstract：:Summary.  Directly acting antiviral (DAA) agents are currently revolutionizing the treatment of chronic hepatitis C infection. The first generation of these agents have significant limitations including cost issues that are of particular concern in the developing world and a lack of efficacy in genotype 3 patients. Bo...

journal_title：Journal of viral hepatitis

authors： Ahmed F

更新日期：2013-05-01 00:00:00

abstract：SUMMARY:Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to liver biopsy for assessment of histological endpoints of antiviral therapy in chronic hepatitis C (CHC). This study compared two commercially available serum marker panels (HCV FibroSURE and FIBROSpect II) during interfer...

journal_title：Journal of viral hepatitis

authors： Patel K,Benhamou Y,Yoshida EM,Kaita KD,Zeuzem S,Torbenson M,Pulkstenis E,Subramanian GM,McHutchison JG

更新日期：2009-03-01 00:00:00

abstract：:Italy is one of the countries on track with the WHO's agenda to eliminate hepatitis C virus (HCV) by 2030. Healthcare facilities play a crucial role in seeking patients who are infected but have not yet been treated. We assessed the effectiveness of a recall strategy, named 'Telepass' project, for patients exposed to ...

journal_title：Journal of viral hepatitis

authors： Ponziani FR,Santopaolo F,Siciliano M,De Belvis AG,Tortora A,Mora V,Fanali C,Morsella A,Balducci F,Vetrugno G,D'Alfonso ME,Cambieri A,Cauda R,Bellantone R,Sanguinetti M,Pompili M,Gasbarrini A

更新日期：2021-01-09 00:00:00

abstract：:Self-efficacy or confidence in one's ability to successfully engage in goal-directed behaviour has been shown to influence medication adherence across many chronic illnesses. In the present study, we investigated the psychometric properties of a self-efficacy instrument used during treatment for chronic hepatitis C vi...

journal_title：Journal of viral hepatitis

authors： Bonner JE,Esserman D,Evon DM

更新日期：2012-05-01 00:00:00

abstract：:The aim of this work was to estimate the future disease burden of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections in the United States until the year 2030. Two back-calculation models of the HIV and the HCV epidemic were developed. They were based on US epidemiological data regarding prevalen...

journal_title：Journal of viral hepatitis

authors： Deuffic-Burban S,Poynard T,Sulkowski MS,Wong JB

更新日期：2007-02-01 00:00:00

abstract：:Treatment for chronic hepatitis C virus (HCV) infection has rapidly evolved into interferon-free directly acting antiviral regimens (DAA) that result in high sustained virologic response. DAAs primarily work by suppressing HCV replication and rely less on the immune system than interferon-based therapies. However, it ...

journal_title：Journal of viral hepatitis

authors： Shrivastava S,Wilson E,Poonia B,Tang L,Osinusi A,Kohli A,Kottilil S

更新日期：2017-09-01 00:00:00

abstract：:We evaluated the effect of sustained virologic response (SVR) from direct-acting antiviral (DAA)- and interferon-based treatments on hepatocellular carcinoma (HCC) risk in a large population-based cohort in Canada. We used data from the BC Hepatitis Testers Cohort, which includes ~1.3 million individuals tested for HC...

journal_title：Journal of viral hepatitis

authors： Janjua NZ,Wong S,Darvishian M,Butt ZA,Yu A,Binka M,Alvarez M,Woods R,Yoshida EM,Ramji A,Feld J,Krajden M

更新日期：2020-08-01 00:00:00

abstract：:The efficacy of lamivudine re-treatment in chronic hepatitis B (CHB) patients who relapse after HBeAg seroconversion with lamivudine has not been investigated. The aim of this study was to evaluate the efficacy of lamivudine re-treatment in relapsed patients. Among 192 patients who had achieved HBeAg seroconversion wi...

journal_title：Journal of viral hepatitis

authors： Shin JW,Park NH,Park JH,Park JH,Jeong ID,Bang SJ,Joo KR,Kim DH

更新日期：2005-07-01 00:00:00

abstract：:For hepatitis B virus (HBV)-related chronic infection under treatment by nucleos(t)ide analogues (NUCs), HBsAg clearance is the ultimate therapeutic goal but very infrequent. We investigated how HBV envelope protein variability could lead to differential HBsAg clearance on NUCs. For 12 HBV genotype D patients receivin...

journal_title：Journal of viral hepatitis

authors： Velay A,Jeulin H,Eschlimann M,Malvé B,Goehringer F,Bensenane M,Frippiat JP,Abraham P,Ismail AM,Murray JM,Combet C,Zoulim F,Bronowicki JP,Schvoerer E

更新日期：2016-05-01 00:00:00

abstract：:The Andaman and Nicobar Islands, Union Territory of India, are home to six primitive tribes. Studies carried out earlier among these tribes revealed very high rates of hepatitis B infection. We have now studied hepatitis A and E infection among them. A total of 951 serum samples were collected from four accessible tri...

journal_title：Journal of viral hepatitis

authors： Murhekar MV,Sehgal SC,Murhekar KM,Padbhidri SP,Chitambar SD,Arankalle VA

更新日期：2002-07-01 00:00:00

abstract：:Single nucleotide polymorphisms (SNPs) in the interleukin 28B gene (IL28B) are good pretreatment predictors of anti-hepatitis C virus (HCV) therapy with interferon. SNPs of the inosine triphosphatase (ITPA) gene are associated with reduced haemoglobin levels during treatment with ribavirin. The i-densy™ (Arkray, Inc.)...

journal_title：Journal of viral hepatitis

authors： Takahashi H,Mizuta T,Oeda S,Isoda H,Nakashita S,Kawaguchi Y,Izumi N,Hirai M,Kurose K,Iwane S,Eguchi Y,Kimura S,Anzai K,Ozaki I

更新日期：2013-04-01 00:00:00

abstract：:Hepatitis E virus (HEV) represents one of the foremost causes of acute hepatitis globally. Although there is no proven medication for hepatitis E, pegylated interferon-α (IFN-α) has been used as off-label drug for treating HEV. However, the efficacy and molecular mechanisms of how IFN signalling interacts with HEV rem...

journal_title：Journal of viral hepatitis

authors： Zhou X,Xu L,Wang W,Watashi K,Wang Y,Sprengers D,de Ruiter PE,van der Laan LJ,Metselaar HJ,Kamar N,Peppelenbosch MP,Pan Q

更新日期：2016-04-01 00:00:00

abstract：:The association between HBV infection and incident thrombocytopenia among subjects without cirrhosis or splenomegaly is unknown. Therefore, we sought to elucidate the association between HBV infection and the development of thrombocytopenia in a large cohort of apparently healthy men and women. A cohort study was perf...

journal_title：Journal of viral hepatitis

authors： Joo EJ,Chang Y,Yeom JS,Lee YG,Ryu S

更新日期：2017-03-01 00:00:00

abstract：:No studies have reported the long-term effects of entecavir switching in patients with multidrug resistance who developed resistance after lamivudine/adefovir sequential therapy. We evaluated the efficacy of 96 weeks of entecavir therapy in patients with resistance to lamivudine/adefovir sequential therapy. In total, ...

journal_title：Journal of viral hepatitis

authors： Kwak MS,Choi JW,Lee JS,Kim KA,Suh JH,Cho YS,Won SY,Park BK,Lee CK

更新日期：2011-10-01 00:00:00

abstract：:Patients with chronic hepatitis B (HBsAg-positive) are at risk of viral reactivation if rituximab is administered without antiviral treatment, a potentially fatal complication of treatment. Patients with so-called 'resolved hepatitis B virus infection' (HBsAg-negative/cAb-positive) may also be at risk. We performed a ...

journal_title：Journal of viral hepatitis

authors： Mozessohn L,Chan KK,Feld JJ,Hicks LK

更新日期：2015-10-01 00:00:00

abstract：:In chronic hepatitis C, transient elastography (TE) accurately identifies cirrhosis, but its ability to assess significant fibrosis (Metavir > or = F2) is variable. Constitutional and liver disease-related factors may influence TE and here we examined the variables associated with differences. Three hundred consecutiv...

journal_title：Journal of viral hepatitis

authors： Calvaruso V,Cammà C,Di Marco V,Maimone S,Bronte F,Enea M,Dardanoni V,Manousou P,Pleguezuelo M,Xirouchakis E,Attanasio M,Dusheiko G,Burroughs AK,Craxì A

更新日期：2010-07-01 00:00:00

abstract：:Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of patients accessing s...

journal_title：Journal of viral hepatitis

authors： Falade-Nwulia O,Mehta SH,Lasola J,Latkin C,Niculescu A,O'Connor C,Chaulk P,Ghanem K,Page KR,Sulkowski MS,Thomas DL

更新日期：2016-05-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a major cause of acute hepatitis in many developing countries. Based on data from nonendemic regions, an animal reservoir of HEV has been proposed; however, data from HEV-endemic regions are limited. We tested sera from 200 pigs, 98 chickens, 86 goats, 58 sheep and 30 buffaloes for anti-HEV ...

journal_title：Journal of viral hepatitis

authors： Shukla P,Chauhan UK,Naik S,Anderson D,Aggarwal R

更新日期：2007-05-01 00:00:00

abstract：:Our study was conducted to further investigate the single-dose approach of hepatitis A vaccination, while providing supportive data on the flexibility of booster administration. Participants received at least one dose of Avaxim 80U Pediatric at 11-23 months of age, and they will be followed for 10 years. We report her...

journal_title：Journal of viral hepatitis

authors： Espul C,Benedetti L,Linares M,Cuello H,Rasuli A

更新日期：2015-04-01 00:00:00