Novel SNPs of the mtDNA ND5 gene and their associations with several growth traits in the Nanyang cattle breed.

Abstract:

:Polymorphism of the mtDNA ND5 gene was detected by PCR-SSCP and DNA sequencing methods in 714 individuals from six Chinese cattle breeds. The results showed that at the P2 locus, two kinds of haplotypes, named A and B, with three SNPs (T12900C, A12923T, C12924T) were detected. The frequencies of haplotype A in six breeds were 0.041-0.167. Polymorphism of the ND5 gene was shown to be associated with growth in the Nanyang breed. Individuals with haplotype B had greater hucklebone width than those with haplotype A when 6 months old (P < 0.01), as well as better body height, body length, body weight, and average daily gain at 6 months (P < 0.05). Therefore, haplotype B of the ND5 gene was likely to have a positive effect on growth traits at 6 months in the Nanyang breed.

journal_name

Biochem Genet

journal_title

Biochemical genetics

authors

Zhang B,Chen H,Hua L,Zhang C,Kang X,Wang X,Pan C,Lan X,Lei C

doi

10.1007/s10528-008-9152-z

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

362-8

issue

5-6

eissn

0006-2928

issn

1573-4927

journal_volume

46

pub_type

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