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Gram-negative intravascular catheter-related bacteremia in patients with spinal cord injury.

Abstract：

OBJECTIVE:To determine whether the prevalence of gram-negative catheter-related bloodstream infection (CRBSI) is higher in patients with spinal cord injury (SCI) than in patients without SCI. DESIGN:Retrospective chart review from August 1998 to August 2006. SETTING:A Veterans Affairs medical center, which serves as a tertiary care medical center to over 500 veterans with SCI and is the primary source of health care for veterans in southeast Texas. PARTICIPANTS:All hospitalized patients who had an International Classification of Diseases, Ninth Revision, code for bacteremia associated with their hospital stay. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURE:The proportion of CRBSI caused by gram-negative organisms in the SCI patients to the proportion of CRBSI caused by gram-negative organisms in the non-SCI patients. RESULTS:Eight (42%) of 19 episodes of CRBSI in the SCI were caused by a gram-negative organism as compared with 4 (11%) of 36 infections in the non-SCI group (P<.01). Factors associated with having a gram-negative organism rather than a gram-positive organism as the causative agent of CRBSI were SCI, femoral catheter site, prolonged hospitalization, decubitus ulcer, and urinary catheter. CONCLUSIONS:In our medical center, patients with SCI who develop CRBSI are more likely to have an infection with a gram-negative organism than are patients without SCI. This knowledge may guide initial empirical therapy of suspected bloodstream infection.

journal_name

Arch Phys Med Rehabil

journal_title

Archives of physical medicine and rehabilitation

authors

Hussain R,Cevallos ME,Darouiche RO,Trautner BW

doi

10.1016/j.apmr.2007.08.151

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

339-42

issue

2

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(07)01691-7

journal_volume

89

pub_type

杂志文章

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