Long-term survivors after chemotherapy in advanced non-small cell lung cancer.

abstract：AIM:The aim of the present study was to evaluate the correlation between WT1 expression levels and clinical features, to investigate the prognostic value of WT1 expression and to use lentiviral constructs to examine whether overexpression of WT1 affects cell proliferation and invasion in ovarian cancer patients. MATER...

journal_title：Anticancer research

authors： Liu Z,Yamanouchi K,Ohtao T,Matsumura S,Seino M,Shridhar V,Takahashi T,Takahashi K,Kurachi H

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Bisphosphonates (BPs) are considered the standard of care in metastatic breast cancer (MBC) patients with bone metastases. Because the survival for these patients may be prolonged compared with those patients with visceral metastases, they may be prescribed BPs for several years. The effects of this long-ter...

journal_title：Anticancer research

authors： Simmons C,Amir E,Dranitsaris G,Clemons M,Wong B,Veith R,Cole DE

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are a third population of lymphocytes that can kill certain tumor cells. This killing is regulated by signals received through activating and inhibitory receptors. 2B4 (CD244), a member of the CD2 subset of Immunoglobulin superfamily, was identified as an activating receptor on NK c...

journal_title：Anticancer research

authors： Johnson LA,Vaidya SV,Goldfarb RH,Mathew PA

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Long non-coding RNA differentiation antagonizing non-protein coding RNA (DANCR) is considered to be an oncogene in many cancer types. However, the role of DANCR in diagnosis and progression of hepatocellular carcinoma (HCC) is still unknown. PATIENTS AND METHODS:In this study, 146 participants including hea...

journal_title：Anticancer research

authors： Ma X,Wang X,Yang C,Wang Z,Han B,Wu L,Zhuang L

更新日期：2016-12-01 00:00:00

abstract：:Concentrations of soluble CD44 standard (sCD44std) and CD44 variant 6 (sCD44v6) isoforms were determined in the sera of 59 patients with distant metastasis from breast cancer receiving second line hormone- or chemotherapy, in comparison to 46 breast cancer patients without detectable recurrent disease and 21 healthy b...

journal_title：Anticancer research

authors： Kopp R,Classen S,Wolf H,Gholam P,Possinger K,Wilmanns W

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated the efficacy and safety of carbon-ion radiotherapy (CIRT) alone for Stage III non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS:Data of 65 patients (median age=73 years) with Stage III NSCLC who underwent CIRT alone in the QST Hospital, Chiba, Japan, between 1997 and 2015 were retros...

journal_title：Anticancer research

authors： Anzai M,Yamamoto N,Hayashi K,Nakajima M,Nomoto A,Ogawa K,Tsuji H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:To assess the prophylactic efficacy of postoperative single intravesical instillation with pirarubicin (THP) and mitomycin C (MMC) for low-risk non-muscle-invasive bladder cancer (NMBC). PATIENTS AND METHODS:A total of 103 clinically low-risk NMBC patients were preoperatively randomized into either THP (n=4...

journal_title：Anticancer research

authors： Yamamoto S,Kageyama Y,Fujii Y,Aizawa T,Urakami S,Fukui I

更新日期：2020-09-01 00:00:00

abstract：:Several lines of evidence have postulated that reduction in the activity of lipoprotein lipase (LPL) is involved in cachexia induction in cancer patients. Recently we have demonstrated that murine melanoma B16 has the ability to reduce the LPL activity and thereby induce cachexia symptoms in mice following intraperito...

journal_title：Anticancer research

authors： Tsujimoto S,Kawamura I,Inami M,Lacey E,Nishigaki F,Naoe Y,Manda T,Goto T

更新日期：2000-09-01 00:00:00

abstract：:Curcumin's instability and its metabolite, tetrahydrocurcumin (THC) pose a major issue for the establishment of dependable pharmacokinetics and excretion profiles. Additional pharmacokinetic variances are associated with durations of intravenous infusions. We found that stabilizing curcumin with phosphoric acid allows...

journal_title：Anticancer research

authors： Helson L,Bolger G,Majeed M,Vcelar B,Pucaj K,Matabudul D

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the effect of breast cancer adjuvant therapies on the levels of circulating surfactant protein-D (SP-D), C-Reactive protein (CRP) and soluble receptor for advanced glycation end-products (sRAGE), as potential biomarkers of subclinical pulmonary inflammation. MATERIAL...

journal_title：Anticancer research

authors： Piperis M,Provatopoulou X,Sagkriotis A,Kalogera E,Ampatzoglou E,Zografos GC,Athanasiou E,Gounaris A

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The association of TN expression, tumour grading and expression of commonly used histopathologic prognostic factors (p53 and estrogen receptor) was examined in 62 cases of invasive ductal carcinoma of the breast. MATERIAL AND METHODS:Following histological grading immunohistochemical reactions were undertak...

journal_title：Anticancer research

authors： Tökés AM,Hortoványi E,Csordás G,Kulka J,Mózes G,Hatalyák A,Kádár A

更新日期：1999-01-01 00:00:00

abstract：:Mediation of cellular interactions by protein (lectin)-carbohydrate recognition presupposes the expression of respective surface determinants. Due to the importance of cellular contacts between bone marrow stromal cells, recently shown to express cell surface lectins, and tumor or normal progenitor cells for biosignal...

journal_title：Anticancer research

authors： Gabius S,Joshi SS,Gabius HJ,Sharp JG

更新日期：1991-03-01 00:00:00

abstract：:Chemopreventative phytochemicals having antitumour and antioxidant properties can overcome problems of chemoresistance and nonspecific toxicity towards normal cells that are associated with platinum-based chemotherapy against cancer. These agents exert their effects by bringing into play numerous cellular proteins tha...

journal_title：Anticancer research

authors： Nessa MU,Beale P,Chan C,Yu JQ,Huq F

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) play a key role in extracellular matrix (ECM) turnover and remodeling. Changes in their expression levels have been observed in various tumor types. However, their clinical significance and prognostic importance in the progr...

journal_title：Anticancer research

authors： Honkavuori M,Talvensaari-Mattila A,Puistola U,Turpeenniemi-Hujanen T,Santala M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Initial U.S.A. breast cancer screening rates have risen, but not repeat screening, especially among low-income minority populations. Latinas are particularly at-risk of underscreening. Consequently, late-detection is common, with increased risk of dying after diagnosis. Why women with low-income, particularl...

journal_title：Anticancer research

authors： Terán L,Baezconde-Garbanati L,Márquez M,Castellanos E,Belkić K

更新日期：2007-11-01 00:00:00

abstract：:A female patient with stage IV-M1c (distant lymph node and breast metastases), chemotherapy-refractory melanoma was treated with the cytotoxic T-lymphocyte antigen 4 (CTLA-4)-inhibitory monoclonal antibody ipilimumab. At first evaluation following induction treatment, there was marked increase in the volume of the lym...

journal_title：Anticancer research

authors： Wilgenhof S,Morlion V,Seghers AC,Du Four S,Vanderlinden E,Hanon S,Vandenbroucke F,Everaert H,Neyns B

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND/AIM:4H-1-Benzopyran-4-ones (chromones) provide a backbone structure for the chemical synthesis of potent anticancer drugs. In contrast to 2-(N-cyclicamino)chromones, the biological activity of 3-(N-cyclicamino)chromones has not been reported. In this study, cytotoxicity of 15 3-(N-cyclicamino)chromone deriva...

journal_title：Anticancer research

authors： Shi H,Nagai J,Sakatsume T,Bandow K,Okudaira N,Uesawa Y,Sakagami H,Tomomura M,Tomomura A,Takao K,Sugita Y

更新日期：2018-08-01 00:00:00

abstract：:Despite the advances in the detection and treatment of lung cancer, the overall 5-year survival is only 10-20%. Accumulating evidence suggests that verapamil, a calcium channel antagonist, is a potential anticancer agent. Epidermal growth factor receptor (EGFR) is a key therapeutic target in many types of cancer, wher...

journal_title：Anticancer research

authors： Zhang C,Lv F,Zhou L,Li X,Wu XX,Hoffman RM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIM:To investigate the impact of inguinal lymph node dissection (ILND) following neoadjuvant chemoradiotherapy (NACRT) for rectal cancer patients with ILN metastasis. PATIENTS AND METHODS:Forty-three patients with rectal cancer underwent NACRT followed by curative surgery between January 2005 and December 2...

journal_title：Anticancer research

authors： Ueta K,Matsuda T,Yamashita K,Hasegawa H,Mukohyama J,Yamamoto M,Matsuda Y,Kanaji S,Oshikiri T,Nakamura T,Suzuki S,Kakeji Y

更新日期：2019-10-01 00:00:00

abstract：:Total sialic acid (TSA) and "lipid-bound" sialic acid (LSA) were evaluated in comparison to carcinoembryonic antigen (CEA) and ferritin and neuron specific enolase (NSE) in 152 untreated patients with primary lung cancer, 107 benign pulmonary disease patients and 207 notmal controls. The mean concentrations of TSA, LS...

journal_title：Anticancer research

authors： Kakari S,Stringou E,Toumbis M,Ferderigos AS,Poulaki E,Chondros K,Dema A,Kotsovoulou V,Pavlidis N

更新日期：1991-11-01 00:00:00

abstract：:Metastatic pancreatic malignant melanoma is considered to be a highly aggressive neoplasm, and only few metastasectomies for lesions originating from the skin or the ocular region have been reported. We report a case of resection of pancreatic metastasis of malignant melanoma originating from the nasal cavity. An isol...

journal_title：Anticancer research

authors： Sugimoto M,Gotohda N,Kato Y,Takahashi S,Kinoshita T,Shibasaki H,Kojima M,Ochiai A,Zenda S,Akimoto T,Konishi M

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Tumorigenesis is a multistep process that begins with the abrogation of normal controls of apoptosis and cell proliferation, and the FAS receptor-ligand system is a key regulator of apoptosis. The aim of this study was to investigate whether functional polymorphisms of death pathway genes (FAS and FASL) are ...

journal_title：Anticancer research

authors： Hsu PI,Lu PJ,Wang EM,Ger LP,Lo GH,Tsay FW,Chen TA,Yang HB,Chen HC,Lin WS,Lai KH

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Taxane-based chemotherapy is useful for peritoneal dissemination control in advanced/recurrent gastric cancer; however, insufficient relative dose intensity (RDI) may preclude disease control achievement. Nab-paclitaxel, with high tumour permeability, is a promising second- or later-line treatment. PATIENTS...

journal_title：Anticancer research

authors： Kanazawa Y,Fujita I,Kakinuma D,Arai H,Matsuno K,Shimoda T,Ko K,Kato S,Uchida E

更新日期：2017-05-01 00:00:00

abstract：:The time course and characteristics of the tumor marker CASA (Cancer Associated Serum Antigen) during the menstrual cycle were analysed. We investigated whether hormonal influences in women and the score of this tumor marker ought to be considered in diagnosis. It could be demonstrated that CASA is not influenced by p...

journal_title：Anticancer research

authors： Meisel M,Römer T,Straube W

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer that disproportionately affects women with darker skin. Epidemiological studies indicate that higher vitamin D levels prevent incidence of TNBC and translate to higher survival rates in those that have TNBC. MATERIALS AND METHODS:Th...

journal_title：Anticancer research

authors： Richards SE,Weierstahl KA,Kelts JL

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:In head and neck squamous cell carcinoma (HNSCC), a variety of immunomodulatory mediators contribute to strongly impaired immune functions. The secretion of C-reactive protein (CRP) by HNSCC cells and its influence on human myeloid dendritic cells (MDC) was investigated. MATERIALS AND METHODS:The CRP levels...

journal_title：Anticancer research

authors： Frenzel H,Pries R,Brocks CP,Jabs WJ,Wittkopf N,Wollenberg B

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Human neuroblastoma and medulloblastoma express abnormal ganglioside patterns especially GD2 and GM2 which are important for tumour growth. We tested the effects of L-cycloserine (L-CS), a potent inhibitor of synthesis of glycosphingolipids, on the growth, viability and expression of GD2 and GM2 in neuroblas...

journal_title：Anticancer research

authors： Cinatl J Jr,Cinatl J,Kotchetkov R,Pouckova P,Vogel JU,Rabenau H,Michaelis M,Kornhuber B

更新日期：1999-11-01 00:00:00

abstract：INTRODUCTION:Malignant tumors of the sweat glands are very rare. Clear cell hidradenoma is a lesion with histopathological features resembling those of eccrine poroma and eccrine spiradenoma. The biological behavior of the tumor is aggressive, with local recurrences reported in more than 50% of the surgically-treated c...

journal_title：Anticancer research

authors： Liapakis IE,Korkolis DP,Koutsoumbi A,Fida A,Kokkalis G,Vassilopoulos PP

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:To identify immunosuppressive elements present in ovarian cancer associated ascites. PATIENTS AND METHODS:Ascites and plasma were obtained from ovarian, primary peritoneal or fallopian tube cancer patients. Surface markers were identified by fluorescence-activated cell sorting (FACS). Cytokine and chemokine...

journal_title：Anticancer research

authors： Giuntoli RL 2nd,Webb TJ,Zoso A,Rogers O,Diaz-Montes TP,Bristow RE,Oelke M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Due to the longer life expectancy of the world's population, the number of elderly cirrhotic patients undergoing surgery for hepatocellular carcinoma (HCC) is increasing. Our study evaluates the benefits of hepatic resections for HCC in cirrhotic patients aged over 65, analysing the early and long-term surgi...

journal_title：Anticancer research

authors： Mercantini P,Corigliano N,Lucandri G,Balducci G,Amodio PM,Ramacciato G,Ziparo V

更新日期：2002-11-01 00:00:00