Abstract:
:HIV infection is associated with impairments in prospective memory (ProM), an aspect of episodic memory that refers to the ability to execute a future intention, such as remembering to take a medication at a specific time. The current study sought to examine the relationship between HIV-associated ProM impairment and the successful management of instrumental activities of daily living (IADLs). In a cohort of 66 HIV-infected individuals, ProM accounted for a significant proportion of variance in self-reported IADL dependence, over and above that which was explained by retrospective memory and by current affective distress. Analysis of component cognitive processes revealed that the relationship between HIV-associated ProM deficits and IADL dependence was driven by impaired cue detection and by deficits in self-initiated intention retrieval. Results were not better explained by demographic factors, HIV disease severity, psychiatric comorbidity, or substance use. Collectively, these data support the potential incremental ecological validity of ProM as a predictor of dependence in IADLs among persons living with HIV infection.
journal_name
Neuropsychologyjournal_title
Neuropsychologyauthors
Woods SP,Iudicello JE,Moran LM,Carey CL,Dawson MS,Grant I,HIV Neurobehavioral Research Center Group.doi
10.1037/0894-4105.22.1.110subject
Has Abstractpub_date
2008-01-01 00:00:00pages
110-7issue
1eissn
0894-4105issn
1931-1559pii
2008-00382-012journal_volume
22pub_type
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