The risk of simple febrile seizures after immunisation with a new group B meningococcal vaccine, New Zealand.

Abstract:

:As part of safety monitoring during a group B meningococcal disease vaccination campaign in New Zealand, we examined the possible excess risk of vaccine-associated simple febrile seizures (SFS). We conducted a cohort analysis using data from active hospital-based surveillance in the South Auckland area and a national immunisation register. Based on analysis of approximately 63,000 doses, we found no statistically significant increase in SFS incidence within 1, 2, 4, or 7 days after vaccination for any/all doses administered to children aged 6 months through 4 years. We concluded that the vaccine is unlikely to induce a heightened risk of SFS.

journal_name

Vaccine

journal_title

Vaccine

authors

Stehr-Green P,Radke S,Kieft C,Galloway Y,McNicholas A,Reid S

doi

10.1016/j.vaccine.2007.12.001

subject

Has Abstract

pub_date

2008-02-06 00:00:00

pages

739-42

issue

6

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(07)01446-6

journal_volume

26

pub_type

杂志文章

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