The influence of socio-economic and surveillance characteristics on breast cancer survival: a French population-based study.

abstract：BACKGROUND:Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are commonly used antihypertensives. Recently, these drugs have been associated with a protective effect against pancreatic cancer, but data on this putative association remain limited. Thus, the objective of this study...

journal_title：British journal of cancer

authors： Mandilaras V,Bouganim N,Yin H,Asselah J,Azoulay L

更新日期：2017-01-03 00:00:00

abstract：:Temozolomide, an imidazotetrazine derivative, was given to 18 patients with low-grade non-Hodgkin's lymphoma (NHL) at a dose of 750 mg m-2 orally, divided over five consecutive days, escalated to 1000 mg m-2 over 5 days (i.e. 200 mg m-2 day-1) if no significant myelosuppression was noted at day 22 of the 28 day cycle....

journal_title：British journal of cancer

authors： Woll PJ,Crowther D,Johnson PW,Soukop M,Harper PG,Harris M,Brampton MH,Newlands ES

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:A frequent mechanism of acquired multidrug resistance in human cancers is overexpression of ATP-binding cassette transporters such as the Multi-Drug Resistance Protein 1 (MDR-1). Nutlin-3, an MDM2-p53 antagonist, has previously been reported to be a competitive MDR-1 inhibitor. METHODS:This study assessed w...

journal_title：British journal of cancer

authors： Chen L,Zhao Y,Halliday GC,Berry P,Rousseau RF,Middleton SA,Nichols GL,Del Bello F,Piergentili A,Newell DR,Lunec J,Tweddle DA

更新日期：2014-08-12 00:00:00

abstract：:In order to examine in detail the sensitivity to chemotherapy of tumour cells at various organ sites and at various stages of metastasis, we have used a series of cell lines, all selected from sister subpopulations derived from a single mouse mammary tumour, which can be distinguished and quantitated from normal cells...

journal_title：British journal of cancer

authors： Miller BE,Miller FR,Machemer T,Heppner GH

更新日期：1993-07-01 00:00:00

abstract：:Alveolar macrophage (AM) phagocytic activity and glucose metabolism were evaluated during lung tumour growth in adult rats challenged i.v. with 10(5) viable Walker 256 tumour cells. Phagocytosis was estimated by the in vitro uptake of (14)C-labelled Pseudomonas aeruginosa and glucose oxidation was evaluated by (14)CO(...

journal_title：British journal of cancer

authors： Gudewicz PW,Saba TM

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Dysplasia is a marker of cancer risk in Barrett's oesophagus (BO), but this risk is variable and diagnosis is subject to inter-observer variability. Cancer risk in BO is increased when chromosomal instability is present. Nucleotyping (NT) is a new method that uses high-resolution digital images of nuclei to ...

journal_title：British journal of cancer

authors： Dunn JM,Hveem T,Pretorius M,Oukrif D,Nielsen B,Albregtsen F,Lovat LB,Novelli MR,Danielsen HE

更新日期：2011-10-11 00:00:00

abstract：:Window of opportunity trials exploit the 'window' of time after cancer diagnosis, typically prior to initiation of cancer therapy. In recent years this study design has become a more regular feature of drug development, as this 'window' provides an opportunity to carry out a thorough pharmacodynamic assessment of a th...

journal_title：British journal of cancer

authors： Aroldi F,Lord SR

更新日期：2020-01-01 00:00:00

abstract：:The co-injection of extracellular matrix components, such as Matrigel, with human tumour cells into nude mice has been reported to facilitate tumour formation and growth, but it is unknown whether such components exert similar effects on tumour progression and metastasis. Metastatic behaviour is known to be enhanced w...

journal_title：British journal of cancer

authors： Bao L,Matsumura Y,Baban D,Sun Y,Tarin D

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Oestrogen (E2) induces apoptosis in long-term E2-deprived MCF7 cells (MCF7:5C). Taxanes have been used extensively in the treatment of early and advanced breast cancer. We have interrogated the sequence of events that involve the apoptotic signalling pathway induced by E2 in comparison with paclitaxel. METH...

journal_title：British journal of cancer

authors： Obiorah I,Sengupta S,Fan P,Jordan VC

更新日期：2014-03-18 00:00:00

abstract：:In 101 breast cancer patients, measurement of oestrogen receptor status in multiple biopsies across a tumour reveals a highly significant difference in the proportion of patients remaining either disease-free (P less than 0.04) or alive (P less than 0.005), when those with uniformly receptor positive (++) primary tumo...

journal_title：British journal of cancer

authors： Castagnetta L,Traina A,Di Carlo A,Carruba G,Lo Casto M,Mesiti M,Leake R

更新日期：1989-04-01 00:00:00

abstract：:The relationship between skin tumours in man and exposure to polyaromatic hydrocarbons has been studied in lathe operators exposed to cutting oils. Seven cases of scrotal cancer and 13 cases of senile keratosis and keratoacanthoma were observed. The risk varied as the 1.6th power of duration of exposure for cancer on ...

journal_title：British journal of cancer

authors： Järvholm B,Easton D

更新日期：1990-12-01 00:00:00

abstract：:The brain-specific angiogenesis inhibitor 1 gene has been isolated in an attempt to find fragments with p53 "functional" binding sites. As reported herein and by others, brain-specific angiogenesis inhibitor 1 expression is present in some normal tissues, but is reduced or lost in tumour tissues. Such data and its par...

journal_title：British journal of cancer

authors： Duda DG,Sunamura M,Lozonschi L,Yokoyama T,Yatsuoka T,Motoi F,Horii A,Tani K,Asano S,Nakamura Y,Matsuno S

更新日期：2002-02-01 00:00:00

abstract：:The tumour vasculature is vital for the establishment, growth and metastasis of solid tumours. Its physiological properties limit the effectiveness of conventional anti-cancer strategies. Therapeutic approaches directed at the tumour vasculature are reviewed, suggesting the potential of anti-angiogenesis and the targe...

journal_title：British journal of cancer

authors： Baillie CT,Winslet MC,Bradley NJ

更新日期：1995-08-01 00:00:00

abstract：:In this single-centre study of 881 patients, S-phase fraction (SPF) was shown to be a significant prognostic marker in terms of overall survival (OS), relapse-free survival (RFS) and survival after relapse (SAR). Further, SPF had independent prognostic significance when considering a range of other clinicopathological...

journal_title：British journal of cancer

authors： Camplejohn RS,Ash CM,Gillett CE,Raikundalia B,Barnes DM,Gregory WM,Richards MA,Millis RR

更新日期：1995-01-01 00:00:00

abstract：:Several radiotherapeutic schedules compatible with continued structural-functional integrity of the gastrointestinal (GI) mucosa were compared utilizing the P815X2 murine mastocytoma grown as a solid subcutaneous tumour. Both the tumour and underlying normal tissues were irradiated during the treatments. The tumour ex...

journal_title：British journal of cancer

authors： Schenken LL,Poulakos L,Hagemann RF

更新日期：1975-02-01 00:00:00

abstract：:Natural human interferon beta (beta-IFN) was tested during the early phase of in vitro infection with HTLV-I virus of human cord blood mononuclear cells (CBL), to evaluate whether its antiviral and immunomodulating effects might prevent spreading of infection in the host. beta-IFN was found to reduce HTLV-I transmissi...

journal_title：British journal of cancer

authors： D'Onofrio C,Perno CF,Mazzetti P,Graziani G,Calio' R,Bonmassar E

更新日期：1988-05-01 00:00:00

abstract：:We used the nationwide Swedish Family-Cancer Database with 2060 childhood brain tumours diagnosed in the period 1958-1996 to analyse the risk of this tumour by parental cancers and in siblings of childhood brain tumour probands. Groups of patients were compared by calculating standardized incidence ratios (SIRs) for b...

journal_title：British journal of cancer

authors： Hemminki K,Li X,Vaittinen P,Dong C

更新日期：2000-08-01 00:00:00

abstract：:Using a recently developed model for studying the biology of locally recurrent (LR) mammary tumours in the 13762NF rat mammary adenocarcinoma system, we examined the sensitivity to polymorphonuclear cell, macrophage and natural killer cell cytolysis. The parental MTF7(T20) cell line; the 'primary' tumours which arose ...

journal_title：British journal of cancer

authors： Aeed PA,Welch DR

更新日期：1988-12-01 00:00:00

abstract：:The ability of human tumour cells to form colonies in soft agar is enhanced by the presence of autologous phagocytic/adherent cells. We investigated the effect of irradiation on the ability of the adherent cells to support human tumour colony formation. Relatively low doses of irradiation significantly increased the g...

journal_title：British journal of cancer

authors： Hamburger AW,White CP,Dunn FE

更新日期：1983-11-01 00:00:00

abstract：:Disseminating disease is a predictive and prognostic indicator of poor outcome in children with neuroblastoma. Its accurate and sensitive assessment can facilitate optimal treatment decisions. The International Neuroblastoma Risk Group (INRG) Task Force has defined standardised methods for the determination of minimal...

journal_title：British journal of cancer

authors： Beiske K,Burchill SA,Cheung IY,Hiyama E,Seeger RC,Cohn SL,Pearson AD,Matthay KK,International neuroblastoma Risk Group Task Force.

更新日期：2009-05-19 00:00:00

abstract：BACKGROUND:Laboratory studies suggest a possible role of magnesium intake in colorectal carcinogenesis but epidemiological evidence is inconclusive. METHOD:We tested magnesium-colorectal cancer hypothesis in the Nurses' Health Study, in which 85 924 women free of cancer in 1980 were followed until June 2008. Cox propo...

journal_title：British journal of cancer

authors： Zhang X,Giovannucci EL,Wu K,Smith-Warner SA,Fuchs CS,Pollak M,Willett WC,Ma J

更新日期：2012-03-27 00:00:00

abstract：:The ability of 5-aminolaevulinic acid and some of its esterified derivatives to induce porphyrin accumulation has been examined in CaNT murine mammary carcinoma cells growing in culture and as tumours in vivo. Topical or intravenous administration of 5-aminolaevulinic acid-esters to mice bearing subcutaneous tumours p...

journal_title：British journal of cancer

authors： Tunstall RG,Barnett AA,Schofield J,Griffiths J,Vernon DI,Brown SB,Roberts DJ

更新日期：2002-07-15 00:00:00

abstract：:Acquired drug resistance is a major problem in cancer treatment. To explore the genes involved in chemosensitivity and resistance, 10 human tumour cell lines, including parental cells and resistant subtypes selected for resistance against doxorubicin, melphalan, teniposide and vincristine, were profiled for mRNA expre...

journal_title：British journal of cancer

authors： Rickardson L,Fryknäs M,Dhar S,Lövborg H,Gullbo J,Rydåker M,Nygren P,Gustafsson MG,Larsson R,Isaksson A

更新日期：2005-08-22 00:00:00

abstract：BACKGROUND:Genome-wide association studies (GWASs) have enriched the fields of genomics and drug development. Adrenocortical carcinoma (ACC) is a rare cancer with a bimodal age distribution and inadequate treatment options. Paediatric ACC is frequently associated with TP53 mutations, with particularly high incidence in...

journal_title：British journal of cancer

authors： Surakhy M,Wallace M,Bond E,Grochola LF,Perez H,Di Giovannantonio M,Zhang P,Malkin D,Carter H,Parise IZS,Zambetti G,Komechen H,Paraizo MM,Pagadala MS,Pinto EM,Lalli E,Figueiredo BC,Bond GL

更新日期：2020-04-01 00:00:00

abstract：:One hundred and one histologically confirmed gastric cancer patients in Gwynedd, North Wales, were matched by sex, age and social class to two hospital inpatients without cancer. Seventy-seven of the gastric cancer cases were also matched, using the same criteria, to a patient with a confirmed cancer of a different si...

journal_title：British journal of cancer

authors： Galpin OP,Whitaker CJ,Whitaker R,Kassab JY

更新日期：1990-05-01 00:00:00

abstract：:Cellular adhesion molecules have been implicated in tumour progression and metastasis. This study examines for the first time the serum concentrations of circulating VCAM-1 and E-selectin in a consecutive series of 110 cancer patients seen in a general medical oncology clinic, and confirms and extends previous studies...

journal_title：British journal of cancer

authors： Banks RE,Gearing AJ,Hemingway IK,Norfolk DR,Perren TJ,Selby PJ

更新日期：1993-07-01 00:00:00

abstract：:A phase I study of the bispecific antibody MDX-H210 in combination with granulocyte colony-stimulating factor (G-CSF) was performed in stage IV breast carcinoma patients, overexpressing HER-2/neu. MDX-H210, constructed by crosslinking antigen binding fragments (F(ab') fragments) of monoclonal antibody (mAb) H22 to Fc ...

journal_title：British journal of cancer

authors： Repp R,van Ojik HH,Valerius T,Groenewegen G,Wieland G,Oetzel C,Stockmeyer B,Becker W,Eisenhut M,Steininger H,Deo YM,Blijham GH,Kalden JR,van de Winkel JG,Gramatzki M

更新日期：2003-12-15 00:00:00

abstract：:In the years before human immunodeficiency virus (HIV) infection, the incidence of Kaposi's sarcoma varied markedly across the African continent, and it was a disease primarily affecting men. In contrast, the evidence reviewed here shows that the causal virus-Kaposi's sarcoma associated herpesvirus (KSHV)-is prevalent...

journal_title：British journal of cancer

authors： Dedicoat M,Newton R

更新日期：2003-01-13 00:00:00

abstract：:The zinc finger protein glioma-associated oncogene homologue 1 (Gli-1) is a critical component of the Hedgehog (Hh) signalling pathway, which is essential for morphogenesis and stem-cell renewal, and is dysregulated in many cancer types. As data were not available on the role of Gli-1 expression in oesophageal cancer ...

journal_title：British journal of cancer

authors： Yoshikawa R,Nakano Y,Tao L,Koishi K,Matsumoto T,Sasako M,Tsujimura T,Hashimoto-Tamaoki T,Fujiwara Y

更新日期：2008-05-20 00:00:00

abstract：:The childhood peak of common acute lymphoblastic leukaemia has been proposed as being a rare response to delayed exposure to a common infection. In this context, factors related to the child's immune system are of special interest. Information on such factors was obtained in a recent German case-control study comprisi...

journal_title：British journal of cancer

authors： Schüz J,Kaletsch U,Meinert R,Kaatsch P,Michaelis J

更新日期：1999-05-01 00:00:00