Abstract：
:Stimulation of a region within the parvocellular medullary reticular formation (PcRF) that contains somas of premotor interneurons produces short latency inhibitory synaptic potentials (IPSPs) in cat trigeminal motoneurons. The present study was undertaken to determine whether glycinergic synapses are responsible for these IPSPs. The intravenous administration of strychnine, an established glycine antagonist, abolished these PcRF-IPSPs. This effect appears to be specific for glycinergic inhibitory synapses because the short lasting component of the IPSP produced by inferior alveolar nerve (IAN) stimulation was also abolished, whereas, in contrast, the long lasting non-glycinergic component of this IPSP was not suppressed. These results indicate that a glycinergic system in the reticular formation is responsible for the non-reciprocal postsynaptic inhibition of trigeminal motoneurons.
journal_name
Brain Resjournal_title
Brain researchauthors
Castillo P,Pedroarena C,Chase MH,Morales FRdoi
10.1016/0006-8993(91)90818-gsubject
Has Abstractpub_date
1991-12-20 00:00:00pages
346-9issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(91)90818-Gjournal_volume
567pub_type
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