Theory of mind deficits in chronic schizophrenia: evidence for state dependence.

Abstract:

:There is evidence that people with schizophrenia show specific deficits in theory of mind (ToM). However, it is a matter of debate whether these are trait or state dependent, and the nature of the relationship between ToM deficits and particular symptoms is controversial. This study aimed to shed further light on these issues by (1) examining ToM abilities in 61 individuals with chronic schizophrenia during a stable phase as compared with 51 healthy controls matched by gender, age, educational level and current IQ, and (2) exploring the relationship between ToM and symptoms. Second order verbal stories and a non-verbal picture-sequencing task were used as ToM measures. Results showed no differences in ToM performance between patients and controls on either measure. Subsequent subgrouping of patients into remitted and non-remitted showed a worse performance of non-remitted patients only on second order ToM tasks. Specific ToM deficits were found associated with delusions. Association with negative symptoms was found to be less specific and accounted for by illness chronicity and general cognitive impairment. The results from the present study are in line with models which hypothesise that specific ToM deficits in schizophrenia are state dependent and associated with delusions. Such associations may also be task specific.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Pousa E,Duñó R,Brébion G,David AS,Ruiz AI,Obiols JE

doi

10.1016/j.psychres.2006.05.018

subject

Has Abstract

pub_date

2008-02-28 00:00:00

pages

1-10

issue

1

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(06)00171-5

journal_volume

158

pub_type

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