Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury.

Abstract:

OBJECTIVE:To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). DESIGN:Prospective cohort study. SETTING:Acute inpatient TBI rehabilitation. PARTICIPANTS:Participants were 1748 persons with TBI. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. RESULTS:Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. CONCLUSIONS:The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.

journal_name

Arch Phys Med Rehabil

authors

Vickery CD,Sherer M,Nick TG,Nakase-Richardson R,Corrigan JD,Hammond F,Macciocchi S,Ripley DL,Sander A

doi

10.1016/j.apmr.2007.07.047

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

48-55

issue

1

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(07)01592-4

journal_volume

89

pub_type

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