Abstract：
BACKGROUND:Various stakeholders can have differing opinions regarding ethical review when introducing new procedures with patients. OBJECTIVE:This pilot study examines the way in which Research Ethics Boards (REBs; Institutional Review Boards) and clinical biochemists (CBs; laboratory medicine specialists) differ in their interpretation of what is research and what should be considered common practice versus innovation versus experimentation when introducing new procedures with patients. It also explores whether these groups agree on who is responsible for the ethical review of new procedures. METHODS:A validated case scenario for the introduction of a new diagnostic test into clinical practice was sent to CBs and REBs across Canada. Participants were asked to determine whether the scenario constituted research; whether the test procedure should be considered as experimental, innovative, or commonly accepted care; and whether the project required approval by a REB and, if not, who should be responsible for ethical review. RESULTS:Results showed 81% of 37 CBs and 52% of 27 REBs identified the scenario as research. Responsibility for ethical review was assigned to REBs by 44% of REBs and 54% of CBs. Of all participants, 53% classified the test procedure as 'innovative', 8% as 'experimental', whereas 17% classified it as 'commonly accepted'. CONCLUSIONS:This pilot study indicates a substantial variation in the ethical assessment of innovation in clinical care. This suggests the need to further elaborate on the types of innovation in health care and categorize the nature of the risks associated with each.
journal_name
J Gen Intern Medjournal_title
Journal of general internal medicineauthors
Patenaude J,Grant AM,Xhignesse M,Leblanc F,Courteau Jdoi
10.1007/s11606-007-0410-2subject
Has Abstractpub_date
2008-01-01 00:00:00pages
27-31eissn
0884-8734issn
1525-1497journal_volume
23 Suppl 1pub_type
杂志文章abstract：BACKGROUND:The Ministry of Health, Labour and Welfare of Japan has been promoting participation in scholarly activities for physicians during residency training. However, there is debate regarding whether this is worthwhile for residents. OBJECTIVE:To evaluate residents' opinions of engaging in scholarly activities an...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-009-0970-4
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:Social connectedness exerts strong influences on health, including major depression and suicide. A major component of social connectedness is having individual relationships with close supports, romantic partners, and other trusted members of one's social network. OBJECTIVE:The objective of this study was t...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-020-05692-7
更新日期：2020-07-01 00:00:00
abstract：:This study is a cross-sectional descriptive survey of randomly selected primary care patients and physicians regarding patient, physician, and family roles in end-of-life decision making. The subjects included 329 adult outpatients and 272 practicing physicians. Physicians were more likely than patients to believe the...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1046/j.1525-1497.1998.00008.x
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Heart failure (HF) is a leading cause of hospitalization. Clinical and socio-demographic factors have been associated with cardiac admissions, but little is known about the role of anxiety. We examined whether symptoms of anxiety were associated with cardiac hospitalizations at 12 months in HF patients. METH...
journal_title：Journal of general internal medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s11606-011-1843-1
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:The telephone can facilitate medical care but also result in adverse outcomes leading to telephone-related malpractice suits. Analyzing claims might identify errors amenable to prevention. The objective of the study was to describe medical errors involving the telephone in patient-clinician encounters that s...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-007-0491-y
更新日期：2008-05-01 00:00:00
abstract：BACKGROUND:Disclosure of medical errors is encouraged, but research on how patients respond to specific practices is limited. OBJECTIVE:This study sought to determine whether full disclosure, an existing positive physician-patient relationship, an offer to waive associated costs, and the severity of the clinical outco...
journal_title：Journal of general internal medicine
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1525-1497.2006.00465.x
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Racial disparities in hypertension control contribute to higher rates of cardiovascular mortality among blacks. Patient-physician communication quality is associated with better health outcomes, including blood pressure (BP) control. Both race/ethnicity and BP control may adversely affect communication. OBJ...
journal_title：Journal of general internal medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s11606-009-1051-4
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:There is growing interest in developing systems to overcome barriers for acquiring and interpreting family health histories in primary care. OBJECTIVE:To examine the capacity of three different electronic portals to collect family history from patients and deposit valid data in an electronic health record (...
journal_title：Journal of general internal medicine
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s11606-013-2442-0
更新日期：2013-12-01 00:00:00
abstract：:The purpose of this paper is to address why the three dominant alternatives to compensating physicians (fee-for-service, capitation, and salary) fall short of what is needed to support enhanced primary care in the patient-centered medical home, and the relevance of such payment reforms as pay-for-performance and episo...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-010-1295-z
更新日期：2010-06-01 00:00:00
abstract：:Topic development and structuring a systematic review of diagnostic tests are complementary processes. The goals of a medical test review are to identify and synthesize evidence to evaluate the impacts alternative testing strategies on health outcomes and to promote informed decision making. A common challenge is that...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-012-2007-7
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:To assess whether newer antipsychotic medications are associated with weight gain and development of diabetes. DESIGN:Retrospective cohort study. SETTING:Data from a comprehensive electronic medical record serving an urban public hospital and a citywide network of mental health clinics. PATIENTS/PARTICIPAN...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1111/j.1525-1497.2004.40126.x
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVES:To build health promotion capacity among community residents through a community-based participatory model, and to apply this model to study the nutritional environment of an urban area to better understand the role of such resources in residents' efforts to live a healthy life. DESIGN:A multiphase collabor...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1046/j.1525-1497.2003.21022.x
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Although hip fractures in older adults are associated with a high degree of mortality and disability, the use of advance care planning (ACP) in this population is unknown. OBJECTIVE:To determine the prevalence of ACP and need for surrogate decision-making prior to death in older adults with hip fracture and...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-020-05644-1
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To assess the effect of a program that encourages teamwork between physicians and pharmacists on attempts to lower total cholesterol levels and to meet recommended goals proposed by the National Cholesterol Education Program (NCEP). DESIGN:A single-blind, randomized, controlled trial lasting 6 months. SETTI...
journal_title：Journal of general internal medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s11606-006-5023-7
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:The gap in asthma prevalence, morbidity, and mortality is increasing in low-income racial/ethnic minority groups as compared with Caucasians. In order to address these disparities,alternative beliefs and behaviors need to be identified. OBJECTIVE:To identify causal models of asthma and the context of conven...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1111/j.1525-1497.2006.00624.x
更新日期：2006-12-01 00:00:00
abstract：:Implementation science is focused on developing and evaluating methods to reduce gaps between research and practice. As healthcare organizations become increasingly accountable for equity, quality, and value, attention has been directed to identifying specific implementation strategies that can accelerate the adoption...
journal_title：Journal of general internal medicine
pub_type： 社论
doi：10.1007/s11606-020-06169-3
更新日期：2020-09-11 00:00:00
abstract：BACKGROUND:As children with diabetes transition to adulthood, they may be especially vulnerable to diabetic ketoacidosis (DKA). Cross-national comparisons may inform efforts to avoid this complication. OBJECTIVE:To compare DKA hospitalization rates in the USA and Manitoba, Canada, during the vulnerable years known as ...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-019-05006-6
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:To determine whether echocardiography affects the decisions to use beta blockers or to recommend bacterial endocarditis prophylaxis in patients suspected of having mitral valve prolapse (MVP). DESIGN:Retrospective review of echocardiograms and clinical records. SETTING:Military tertiary care hospital. PATI...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/BF02600871
更新日期：1990-11-01 00:00:00
abstract：:Mycophenolate mofetil (MM) is commonly used in patients with autoimmune diseases or who have undergone transplantation. Common side effects of MM include anemia, leukopenia, mucositis and opportunistic infections. We report an unusual case of pulmonary alveolar proteinosis (PAP) in a 67-year-old woman on MM for Wegene...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-010-1433-7
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) is a growing public health concern that overwhelmingly affects older adults. National guidelines have called for earlier referral of CKD patients, but it is unclear how these should apply to older adults. OBJECTIVE:This scholarly review aims to explore the current literature abo...
journal_title：Journal of general internal medicine
pub_type： 杂志文章,评审
doi：10.1007/s11606-007-0492-x
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:Leaders play a crucial role in implementing and sustaining changes in clinical practice, yet there is limited evidence on the strategies to engage them in team problem solving and communication. OBJECTIVE:Examine the impact of an intervention focused on facilitating leadership during daily huddles on optimi...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-020-06487-6
更新日期：2021-01-26 00:00:00
abstract：BACKGROUND:Mind-body practices such as yoga are widely popular, but little is known about how such exercises impact health-related quality of life. OBJECTIVE:To measure changes in health-related quality of life associated with 3 months of mind-body training as practiced in community-based settings. DESIGN:Prospective...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1111/j.1525-1497.2004.30011.x
更新日期：2004-07-01 00:00:00
abstract：:To assess attitudes toward educational programs about AIDS, 540 patients and 36 of their medical providers in primary care clinics were systematically sampled to ascertain what age groups should be exposed to a pamphlet entitled "Am I at Risk for AIDS?", as well as what was acceptable content for posters and pamphlets...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/BF02596487
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:The Diabetes Prevention Program (DPP) intensive lifestyle intervention resulted in significant weight loss, reducing the development of diabetes, but needs to be adapted to primary care provider (PCP) practices. OBJECTIVES:To compare a DPP-translation using individual (IC) vs. conference (CC) calls delivere...
journal_title：Journal of general internal medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s11606-013-2529-7
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Differences among hospitals in the use of inpatient consultation may contribute to variation in outcomes and costs for hospitalized patients, but basic epidemiologic data on consultations nationally are lacking. OBJECTIVE:The purpose of the study was to identify physician, hospital, and geographic factors t...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-015-3216-7
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Previous studies indicate that medical trainees frequently experience discrimination by patients. Little is known about effective strategies to teach trainees to respond to this discrimination. AIM:To create a workshop for first-year residents utilizing standardized patients to improve skills in responding ...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-019-04881-3
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:Many academic hospitals have implemented overnight hospitalists to supervise house staff and improve outcomes, but few studies have described the impact of this role. OBJECTIVE:To investigate the effect of an overnight academic hospitalist program on patient-level outcomes. Secondary objectives were to desc...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-015-3389-0
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To decrease unnecessary antibiotic use for acute respiratory tract infections in adults in a point-of-service health care setting. DESIGN:Prospective, nonrandomized controlled trial. SETTING:An urban urgent care clinic associated with the major indigent care hospital in Denver, Colorado between October 2000...
journal_title：Journal of general internal medicine
pub_type： 临床试验,杂志文章
doi：10.1046/j.1525-1497.2003.20410.x
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Twenty-eight states have passed breast density notification laws, which require physicians to inform women of a finding of dense breasts on mammography. OBJECTIVE:To evaluate changes in breast cancer stage at diagnosis after enactment of breast density notification legislation. DESIGN:Using a difference-in...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/s11606-016-3904-y
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:To examine the relationship between resident physicians' perceptions of their preventive cardiology practices and a chart audit assessment of their documented services. DESIGN:A criterion standard comparison of two methods used to assess resident physicians' practices: self-report and chart audit. SETTING:P...
journal_title：Journal of general internal medicine
pub_type： 杂志文章
doi：10.1007/BF02600254
更新日期：1995-04-01 00:00:00
