Abstract：
:Noninvasive assessment of endothelial dysfunction (ED) and diagnosing the early vascular development of atherosclerosis in active mucocutaneous Behçet's disease. Twenty-nine active BD patients (study group) without any obstructive vascular involvement were compared with twenty-nine healthy controls (control group) in terms of ED utilizing endothelium-dependent dilation as well as endothelium-independent dilation (FMD), which was assessed by measuring changes in brachial artery diameter following sublingual glyceril trinitrate (400 microg Nitrolingual spray). All patients underwent a complete transthoracic echocardiographic and tissue Doppler study. A standard form was utilized for the documentation of the presence or absence of the known risk factors for atherosclerotic vascular disease. Statistical analysis was performed by utilizing SPSS version 11. There was no difference between patients and controls in terms of echocardiographic and tissue Doppler parameters as well as baseline brachial artery diameters. Flow-mediated dilation showed 38% impairment in study group compared with control (P<0.05). Endothelium-independent NTG dilatation did not differ in both groups. Ultrasonography is an easily applicable noninvasive method for following BD patients for the risk of ED, which may preclude to atherosclerosis, save time and cost-effective.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Ulusoy RE,Karabudak O,Kilicaslan F,Kirilmaz A,Us MH,Cebeci BSdoi
10.1007/s00296-007-0491-6subject
Has Abstractpub_date
2008-05-01 00:00:00pages
617-21issue
7eissn
0172-8172issn
1437-160Xjournal_volume
28pub_type
杂志文章abstract：:The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2937-3
更新日期：2014-08-01 00:00:00
abstract：:A case of relapsing polychondritis with aortic arch aneurysm and aortic arch syndrome is described. The pattern of vascular involvement supports the inclusion of relapsing polychondritis within the spectrum of systemic vasculitides. ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541214
更新日期：1984-01-01 00:00:00
abstract：:Joint destruction and excessive bone formation are associated with high expression of soluble receptor activator of nuclear factor-κB ligand (sRANKL). This study was undertaken to investigate the role of sRANKL in collagenase-induced osteoarthritis (CIOA) in mice and in patients with osteoarthritis (OA). The initial p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1723-8
更新日期：2012-05-01 00:00:00
abstract：:Clinically diagnosed cases with different grades of rheumatoid arthritis (RA) were studied for (a) cryoglobulin content (b) constituents of cryoglobulins, and (c) rheumatoid factor (RF) titers in sera and cryoglobulins. Of 60 patients, 28 (46.66%) had significantly high levels of cryoglobulins and were mainly distribu...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541520
更新日期：1985-01-01 00:00:00
abstract：:In a study of synovial fluid from 110 patients with various forms of arthritis, platelets were identified in the synovial fluid of all the 50 rheumatoids, in 18 out of the 25 (72%) with osteoarthritis and in all 35 of those with other forms of inflammatory osteoarthrosis. Identification of platelets by light microscop...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00683878
更新日期：1984-01-01 00:00:00
abstract：:The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is an inclusive questionnaire, able to describe the total impairments and restrictions due to axial spondyloarthritis (axSpA). Considering the relationship between ASAS HI and the Ankylosing Spondylitis Disease Activity Score (ASDAS)-CRP,...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3642-9
更新日期：2017-05-01 00:00:00
abstract：:Malignant neoplasms are associated with a wide variety of paraneoplastic rheumatological syndromes. The paraneoplastic nature should be based on specific criteria. We report a series of eight cases of paraneoplastic rheumatic syndromes revealing an underlying neoplasia. Our series consists of six men and two women, wi...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-011-2252-9
更新日期：2012-06-01 00:00:00
abstract：:Rheumatology has its roots in ancient Greece. Hippocrates and other prominent Greek (Hellenes) physicians in ancient times, Hellenistic, Roman, and Byzantine period were acute observers of disease course and of patients and were able to define many disorders. They wrote books on various aspects of medicine and these w...
journal_title：Rheumatology international
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s00296-019-04261-4
更新日期：2019-06-01 00:00:00
abstract：:Heart rate variability (HRV) is a useful tool for the detection of sympathetic-parasympathetic balance in the autonomic nervous system. Autonomic nervous system involvement in patients with rheumatoid arthritis (RA) has rarely been studied and has shown conflicting results. Our purpose was to determine if HRV showed c...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0357-5
更新日期：2004-07-01 00:00:00
abstract：:The aim of the study was to assess agreement between three-dimensional volumetric ultrasound (3D US) performed by inexperienced staff and real-time conventional ultrasound (2D US) performed by experienced rheumatologists in detecting and scoring rheumatoid arthritis (RA) lesions. Thirty-one RA patients underwent exami...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3606-0
更新日期：2017-02-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is a severe complex rheumatic disease, but good estimate of its prevalence and risk factors is lacking in China. The aim of the study was to explore the prevalence of SLE and risk factors in rural areas of Anhui Province of China. Eleven counties were randomly selected in Anhui Provi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2902-1
更新日期：2014-03-01 00:00:00
abstract：:The objective of the study was to determine whether cartilage expression of the bone regulating molecules receptor activator of nuclear factor κB ligand (RANKL) and osteoprotegerin (OPG) varies between the different grades of osteoarthritis (OA). Cartilage samples were obtained from 30 patients undergoing total hip/kn...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1733-6
更新日期：2012-02-01 00:00:00
abstract：:The objective was to investigate the effect of activin A on matrix metalloproteinase 3 (MMP-3) production and to identify the role of activin A in chondroprotection. SW1353 cells, a human chondrosarcoma cell line, were stimulated with interleukin (IL) 1alpha and tumor necrosis factor (TNF) alpha, and the concentration...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0350-5
更新日期：2007-09-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is a systemic autoimmune disease affecting up to 1% of the worldwide population. RA is associated with multiple extra-articular manifestations (EAMs). Middle ear, cochlea and the auditory nerve are suspected sites of RA activity and hearing loss is a possible novel EAM of RA. Objective was to...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04609-1
更新日期：2020-11-01 00:00:00
abstract：:We aimed to evaluate the cost-effectiveness of certolizumab pegol (CZP), a pegylated fc-free anti-TNF, as add-on therapy to methotrexate (MTX) versus etanercept, adalimumab, or golimumab in patients with moderate-to-severe active rheumatoid arthritis (RA) not responding to the conventional synthetic disease-modifying ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-017-3736-z
更新日期：2017-09-01 00:00:00
abstract：INTRODUCTION:Early arthritis clinics (EACs) have been well established since 1980s. Most of the data for their effectiveness comes from rheumatoid arthritis (RA) management and is largely limited to process outcomes. There is little evidence that such clinics improve clinical outcomes particularly for psoriatic arthrit...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04253-4
更新日期：2019-04-01 00:00:00
abstract：:We evaluated the presence of sarcopenia in a population of systemic sclerosis (SSc) patients, with respect to nutritional, clinical, and laboratory features. A total of 62 patients who met the ACR/EULAR 2013 classification criteria were enrolled. Sarcopenia was defined according to the Relative Skeletal Mass Index (RS...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04401-w
更新日期：2019-10-01 00:00:00
abstract：:To determine the possible diagnostic and prognostic value of cartilage biomarkers in early-stage progressive and nonprogressive knee osteoarthritis (OA) in a population-based cohort of middle-aged subjects with chronic knee pain. Design tibiofemoral (TF) and patellofemoral (PF) radiographs were graded in 128 subjects ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2463-8
更新日期：2013-04-01 00:00:00
abstract：:Articular involvement is a frequent extrahepatic manifestation of hepatitis C virus (HCV) infection. The distinction between HCV-related polyarthropathy and true RA may be very difficult, especially with recent onset RA before articular damage and erosions develop. The objective of the study is to assess the diagnosti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1225-8
更新日期：2011-01-01 00:00:00
abstract：:Smoking produces substances that activate proinflammatory, prothrombotic and vasoconstrictive mediators via posttranslational carbamylation of proteins. As a new consequence of carbamylation, induction of anti-carbamylated autoantibodies were observed in rheumatoid arthritis (RA) patients, sometimes prior to onset of ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3472-9
更新日期：2016-06-01 00:00:00
abstract：:Juvenile dermatomyositis (JDM) is a rare but complex and potentially life-threatening autoimmune disease of childhood. Significant proportions of patients have residual weakness, muscle atrophy, joint contractures, and calcinosis. Recently, new clinical findings, such as lipodystrophy accompanied with increased fat de...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3031-1
更新日期：2014-11-01 00:00:00
abstract：:It is known that patients with rheumatoid arthritis (RA) have an increased risk for non-Hodgkin's lymphomas in comparison with the general population. Although increased risk of lymphoma is attributed to the disease activity, the drugs used in the therapy of RA may also cause increased risk of malignancy. Herein, we r...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1184-0
更新日期：2011-04-01 00:00:00
abstract：:We characterized the anemia in monkey collagen-induced arthritis (CIA) to evaluate whether this model is useful to analyze the basis of an anemia of inflammatory diseases. Cynomolgus monkey was immunized with bovine type II collagen on days 0 and 21. Blood samples were collected regularly and hematological parameters,...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0547-2
更新日期：2008-07-01 00:00:00
abstract：:Several studies of rheumatoid arthritis (RA) incidence and prevalence indicate that occurrence of the disease varies significantly among different populations. We aimed to estimate the prevalence and incidence of RA in South Korea. We used Korean National Health Insurance (NHI) claims data to estimate the prevalence o...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2590-2
更新日期：2013-06-01 00:00:00
abstract：:CCL28 is a mucosa-associated epithelial-cell-produced chemokine involved in oral defense. We assessed the level of CCL28 in saliva of primary Sjögren's syndrome (pSS) patients in comparison with healthy controls and correlated it with IgA salivary levels. We included 30 non-smoker pSS patients and 30 non-smoker health...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3210-0
更新日期：2015-08-01 00:00:00
abstract：:The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2076-7
更新日期：2012-10-01 00:00:00
abstract：:This study was performed to investigate the frequency of human leukocyte antigen (HLA)-B27 in Chinese patients with suspected of ankylosing spondylitis (AS) and to assess the clinical significance of HLA-B27 typing. A total of 1,016 patients suspected of AS were classified into six groups based on one major AS-related...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1148-4
更新日期：2010-08-01 00:00:00
abstract：:Research suggests that health literacy (HL) is associated with rheumatoid arthritis (RA) patients' functional status. Single-item health literacy screening (SILS) questionnaires may establish patients' HL; however, the wording of SILS may be misinterpreted by RA patients as a query regarding physical limitations. Desp...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3238-9
更新日期：2015-09-01 00:00:00
abstract：:Monocyte interleukin-1 (IL-1) production in vitro was studied in 49 patients with rheumatoid arthritis (RA) and 31 controls. Twenty-six of the RA patients were studied prospectively for up to 12 months after beginning chrysotherapy. About half of the patients (group 1) exhibited pretreatment levels of monocyte IL-1 se...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF02274840
更新日期：1990-01-01 00:00:00
abstract：:Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patien...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1573-4
更新日期：2012-01-01 00:00:00
