Abstract：
:Praziquantel is still very effective for the treatment of schistosomiasis, but there are rising concerns on the potential risk of developing resistances because of the extensive use of this drug. Triclabendazole, a systemic anthelmintic, is very effective against other trematodes such as Paragonimus spp. and Fasciola spp. It has been reported to be effective in vitro and in experimental animals against Schistosoma mansoni. However, its antischistosomal efficacy in humans has not yet been evaluated. The objective of the study was to evaluate the efficacy of triclabendazole at the dosage currently used for the treatment of human fascioliasis (10mg/kg body weight) in subjects co-infected with S. mansoni and Fasciola spp. The study was carried out in Behera, a highly endemic area for both parasites, by personnel of the Egyptian Ministry of Health and Population. Ten subjects (m = 4, f = 6; age, 8-58years), who were infected at the same time by Fasciola spp. and S. mansoni, were enrolled. Six weeks after therapy, seven subjects were still excreting ova of S. mansoni, whereas none was excreting Fasciola spp. ova. At the given dosage, triclabendazole appeared not to be sufficiently effective in the treatment of S. mansoni.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Barduagni P,Hassanein Y,Mohamed M,Wakeel AE,Sayed ME,Hallaj Z,Curtale Fdoi
10.1007/s00436-007-0802-6subject
Has Abstractpub_date
2008-03-01 00:00:00pages
631-3issue
4eissn
0932-0113issn
1432-1955journal_volume
102pub_type
临床试验,杂志文章abstract：:While bivalves can acquire trematode metacercariae over their lifetime, the rate at which this accumulation takes place is not necessarily linear. The present study found that the bivalve Macomona liliana acquires very few or no metacercariae until it reaches 30 mm in size, but thereafter the rate at which it becomes ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1166-2
更新日期：2008-12-01 00:00:00
abstract：:Hymenolepis diminuta is a zoonotic cestode parasitizing the small intestine of rodents (definitive hosts). Humans can accidentally enter into the life cycle of this tapeworm via the ingestion of infected insects (intermediate hosts) containing cestode cysticercoids in their body cavity. More than two centuries after t...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-020-06663-x
更新日期：2020-07-01 00:00:00
abstract：:On the basis of information acquired from local health authorities in Evora district of Portugal on cases of visceral leishmaniasis (VL), an epidemiology survey study was conducted. To determine the prevalence of anti-Leishmania antibodies in the local human and canine populations residing in Evora town and 14 adjacen...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00937115
更新日期：1995-01-01 00:00:00
abstract：:The present study aimed to isolate and genotype strains of T. gondii from pigs slaughtered for human consumption in South Brazil. Blood and tissues (heart, diaphragm, liver, tongue, and masseter) from 400 animals were collected at two slaughterhouses. Sera were obtained, and antibodies against T. gondii were detected ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06274-1
更新日期：2019-05-01 00:00:00
abstract：:Over the past decade, advances in proteomic and mass spectrometry techniques and the sequencing of the Plasmodium falciparum genome have led to an increasing number of studies regarding the parasite proteome. However, these studies have focused principally on parasite protein expression, neglecting parasite-induced va...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2521-2
更新日期：2012-02-01 00:00:00
abstract：:Artesuante (AS) is a good chemoprophylactic drug for preventing against schistosome infection, but Hua et al. recently reported that the sensitivity of AS against Schistosoma japonicum decreased after 10 years of use in China. There are at least three problems, to our knowledge, making the finding suspicious or inconc...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2641-8
更新日期：2012-04-01 00:00:00
abstract：:This study was conducted to evaluate the phytochemical composition and larvicidal effect of leaf essential oil from Murraya exotica against early fourth-instar larvae of Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus. Gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) analyses reve...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4370-x
更新日期：2015-05-01 00:00:00
abstract：:Taenia species of domestic dogs can cause cysticercosis and coenurosis in a wide range of intermediate hosts including humans. Most taeniids of dogs are globally distributed, but some wildlife-transmitted species can be specific for certain regions. Generally, little information exists on the species composition and f...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06793-2
更新日期：2020-09-01 00:00:00
abstract：:Among the topics related to invasion science, the least studied are parasite co-introduction and spillback. This leads to an uncertainty in invasion ecology theories and applications to management. Therefore, the present study brings a systematic review of published information on the metazoan parasite fauna of Microp...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-018-5876-9
更新日期：2018-06-01 00:00:00
abstract：:In the present study, Diplectanum laubieri was redescribed from material obtained from wild and cultured fish. The population dynamics of D. aequans and D. laubieri under culture conditions was studied. The prevalence and mean intensity (average number of worms per parasitized fish) were 80.64% and 112 for D. aequans ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00930906
更新日期：1991-01-01 00:00:00
abstract：:The discovery and optimization of antiparasitic compounds has profited by information-based methods newly emerged in the modern drug development process. The generation of computer models enables the cost-efficient and fast computational screening of virtual compound libraries for biologically active molecules. Two so...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-002-0773-6
更新日期：2003-06-01 00:00:00
abstract：:Clonorchiasis, caused by Clonorchis sinensis infection, is a zoonotic parasitic disease of hepatobiliary system in which the proteins released by adult are major pathogenetic factors. In this study, we first characterized a putative sphingomyelin phosphodiesterase (CsSMPase) A-like secretory protein, which was highly ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3388-1
更新日期：2013-06-01 00:00:00
abstract：:Acetylcholinesterase (AChE) is a key enzyme involved in nerve impulse transmission in both vertebrates and invertebrates. In addition to neuromuscular AChE, many parasitic nematodes synthesize AChE in secretory glands and release the enzyme into their external environment. In this study, we evaluate the activities of ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3878-9
更新日期：2014-06-01 00:00:00
abstract：:Morphology of capsules surrounding acanthocephalan Corynosoma strumosum in paratenic hosts (sea fishes of three species from the northern part of the Sea of Okhotsk) was studied. A thick layer of glycocalyx is formed on the surface of acanthocephalan's tegument in smelts Osmerus mordax dentex and Hypomesus olidus; the...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2088-3
更新日期：2011-02-01 00:00:00
abstract：:A total of 37 juvenile Etmopterus spinax from the Norwegian Deep were examined for stomach contents and metazoan ecto- and endoparasites. These squaliform elasmobranchs were caught by benthopelagic net in May 2001 at a depth of 194-214 m. The euphausiid Meganyctiphanes norvegica and the teleost Maurolicus muelleri wer...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0741-1
更新日期：2003-03-01 00:00:00
abstract：:In the gastrointestinal mucosa, mucus produced by goblet cells plays an important role in the defense against various pathogens. It is well known that some helminth parasites are able to up-regulate goblet cell numbers and alter the mucus components. However, the nature of the interactions between the protozoan parasi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1256-1
更新日期：2009-03-01 00:00:00
abstract：:Biosynthesized nanoparticles have been achieved using environmentally acceptable plant extract and eco-friendly reducing and capping agents. The present study was based on assessments of the larvicidal activities to determine the efficacies of synthesized silver nanoparticles (AgNPs) using aqueous leaf extract of Vinc...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3158-5
更新日期：2013-02-01 00:00:00
abstract：:Members of the Naegleria genus are free-living amoebae, and the only pathogenic specie described to date for humans is N. fowleri. However, as the complete genome of this specie has not been reported, non-pathogenic N. gruberi is employed to describe molecular pathways in N. fowleri. Regardless, certain mechanisms, su...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5293-x
更新日期：2017-01-01 00:00:00
abstract：:Different Tunga penetrans isolates from various hosts obtained from South America (Fortaleza. Brazil) have been studied by nucleotide sequence comparison of the first and the second internal transcribed spacer (ITS1, ITS2) of the ribosomal deoxyribonucleic acid (rDNA) and part of the mitochondrial 16S rDNA. Results sh...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0743-0
更新日期：2008-01-01 00:00:00
abstract：:Nematodes and coccidia are major pathogens causing parasitic infections in livestock production. This study aimed to determine the prevalence and seasonality of gastrointestinal helminths and coccidia in communal sheep grazing in humid, semi-humid and arid zones of the Eastern Cape Province. A total of 3299 faecal sam...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06927-6
更新日期：2020-12-01 00:00:00
abstract：:Nested PCR was used as a diagnostic tool to investigate the presence of Echinococcus multilocularis tapeworm in protected species of carnivores in Slovakia. Twenty-three faecal samples from wolves, four samples from bears and three samples from lynx from the Muránska Planina mountains and eight samples from wolves fro...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360100452
更新日期：2001-10-01 00:00:00
abstract：:Cryptosporidium spp. are common intestinal protozoa causing diarrhea in humans and a variety of animal species. With the recent development of fur industry, a large number of fur animals are farmed worldwide, especially in China. The existence of identical Cryptosporidium species/genotypes in humans and fur animals su...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5686-5
更新日期：2018-01-01 00:00:00
abstract：:Capillaria hepatica (syn. Calodium hepaticum) is a globally distributed nematode with a high affinity to the liver of a wide range of mammalian hosts, including humans. Documented reports of the nematode in cats and associated histopathology are rare. Here, we describe a case of C. hepatica infection in a 5-year-old m...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-021-07056-4
更新日期：2021-01-22 00:00:00
abstract：:The present paper reports the ability of egg-propagated gametocyte vaccine to induce protective immunity against Eimeria tenella infections in offspring chicks. For this purpose, breeding hens were immunized with adjuvanted gametocyte vaccine orally, being the best vaccine in our previous studies. Eggs collected 2 wee...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0382-x
更新日期：2007-04-01 00:00:00
abstract：:The petroleum ether extract of Viola websteri Hemsl. (Violaceae) was investigated for its activity against chloroquine-sensitive strains of Plasmodium falciparum using the parasite lactate dehydrogenase assay method. The main antiplasmodial principles, 6-(8'Z-pentadecenyl)-salicylic acid (1) and 6-(8'Z, 11'Z, 14'Z-hep...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1205-z
更新日期：2009-01-01 00:00:00
abstract：:Myxobolus miyairii Kudo, 1919 was first reported from the intestines of the Amur catfish (Silurus asotus) in Japan and then in China and Russia, but with incomplete description. During the investigation of fish myxosporean diversity in Poyang Lake, the biggest lake along the Yangtze River, China, two Amur catfish high...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4889-x
更新日期：2016-04-01 00:00:00
abstract：:With the advent of polymerase chain reaction (PCR), genetic markers are now accessible for all organisms, including parasites. Amplified fragment length polymorphism (AFLP) is a PCR-based marker for the rapid screening of genetic diversity and intraspecific variation. It is a potent fingerprinting technique for genomi...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-012-3238-6
更新日期：2013-02-01 00:00:00
abstract：:Malaria recurrences after an initially successful therapy and malarial fever occurring a long time after infection are well-known problems in malariology. Currently, two distinct types of malaria recurrences are defined: recrudescence and relapse. A recrudescence is thought to originate from circulating Plasmodium blo...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-016-5043-0
更新日期：2016-06-01 00:00:00
abstract：:The localization and distribution of SALMFamide (S1)-like immunoreactivity (IR), was determined at both the cellular and subcellular level in the central nervous system (CNS) of the nematode roundworm Ascaris suum. The techniques of indirect immunofluorescence in conjunction with confocal scanning laser microscopy and...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050086
更新日期：1996-01-01 00:00:00
abstract：:The present study describes a transmission electron microscopical investigation of trophozoites from Giardia lamblia clone GS/M-83-H7 after exposure to monoclonal antibody (MAb) G10/4. From previous studies it is known that this antibody immunoreacts with the parasite's major surface antigen VSP (variable surface prot...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050096
更新日期：1996-01-01 00:00:00
