Identification of stage-specific proteins of Angiostrongylus vasorum (Baillet, 1866) Kamensky.

Abstract:

:Sera of ten dogs infected with Angiostrongylus vasorum were analyzed by immunoblotting proteins of first stage larvae (L1) and adult parasites. The molecular weights (m.w.) of the principal L1 proteins identified by IgG, IgM, IgA, and IgE were 18-118 kDa and those of the adult parasite were 28-209 kDa. The L1 proteins had not been recognized by IgG, IgM, and IgA antibodies in sera of dogs naturally infected with Toxocara canis, Ancylostoma caninum, and Dipylidium caninum, although only weakly by IgE. Adult parasite proteins were recognized by antibodies in sera of dogs naturally infected with gastrointestinal helminths. Adult parasite proteins with m.w. of approximately 51, 63, 92, and 209 kDa recognized by IgG could be used for specific diagnosis of canine angiostrongylosis.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

De Oliveira Vasconcelos V,De Almeida Vitor RW,Dos Santos Lima W

doi

10.1007/s00436-007-0774-6

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

389-95

issue

3

eissn

0932-0113

issn

1432-1955

journal_volume

102

pub_type

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