Eptifibatide-induced thrombocytopenia.

abstract：:Aspirin has been in use for prevention and management of cardiovascular diseases for several decades. Clinical and epidemiological literature suggests that while net benefits of aspirin in primary prevention of CVDs are less clear, the benefits of aspirin in acute scenarios and secondary prevention settings are well e...

journal_title：Journal of thrombosis and thrombolysis

authors： Ganjehei L,Becker RC

更新日期：2015-11-01 00:00:00

abstract：:The risk benefit decision in providing anticoagulation for patients with brain metastases is amongst the most difficult decisions faced by clinicians. The purpose of our study was to evaluate both the risk of intracerebral hemorrhage (ICH) associated with anticoagulation therapy and the effect of anticoagulation on su...

journal_title：Journal of thrombosis and thrombolysis

authors： Hunter BD,Minichiello T,Bent S

更新日期：2017-10-01 00:00:00

abstract：:We report a case of acquired thrombotic thrombocytopenic purpura (TTP) in a 34-year old patient with a prior diagnosis of systemic lupus erythematosis (SLE) who was recently started on hydroxychloroquine. Presenting symptoms included fevers, sore throat and productive cough with progressive weakness, dyspnea on exerti...

journal_title：Journal of thrombosis and thrombolysis

authors： Mar N,Mendoza Ladd A

更新日期：2011-01-01 00:00:00

abstract：:The occurrence of an inhibitor against coagulation factor V (FV) is a rare but challenging condition, which may span from asymptomatic laboratory abnormalities to potentially life-threatening bleeding. The onset of FV inhibitors has been associated most frequently in the past with the patients' exposure to topical bov...

journal_title：Journal of thrombosis and thrombolysis

authors： Franchini M,Lippi G

更新日期：2011-05-01 00:00:00

abstract：INTRODUCTION:While the CURE trial demonstrated the benefits of clopidogrel in acute coronary syndromes, patients receiving glycoprotein IIb/IIIa antagonists were excluded. Given the frequent coadministration of these two medications, we sought to examine their interaction and their combined effect on platelet inhibitio...

journal_title：Journal of thrombosis and thrombolysis

authors： Talreja D,Lubbe D,Orford JL,Lennon R,DiBattiste PM,Berger PB

更新日期：2004-08-01 00:00:00

abstract：:Aortic stenosis (AS) accounts for the majority of valvular abnormalities requiring surgical intervention. Platelet dysfunction has been demonstrated among patients with severe aortic stenosis which may predispose patients to bleeding or ischemic events. Surgical aortic valve replacement (AVR) is the standard therapy f...

journal_title：Journal of thrombosis and thrombolysis

authors： Lynch DR Jr,Dantzler D,Robbins M,Zhao D

更新日期：2013-05-01 00:00:00

abstract：:Pulmonary embolism (PE) is a leading cause of cardiovascular mortality. We intended to evaluate the awareness and management status of PE among Chinese physicians and provide the basis for establishing Chinese clinical guidelines on PE. We designed a nationwide survey to collect data on physicians' awareness of diagno...

journal_title：Journal of thrombosis and thrombolysis

authors： Zhang M,Zhang YX,Zhang Z,Wang J,Shao X,Xie WM,Wan J,Zhai ZG,Wang C

更新日期：2019-04-01 00:00:00

abstract：:The best strategy in atrial fibrillation (AF) after > 12 months after an acute coronary syndrome or in patients with chronic coronary syndrome without an indication for interventional revascularization remains unclear. European guidelines generally recommend therapy with oral anticoagulation (OAC) alone, whereas North...

journal_title：Journal of thrombosis and thrombolysis

authors： Wernly B,Bhatt DL,Polzin A,Jung C

更新日期：2020-02-01 00:00:00

abstract：:Anticoagulation is often used in superior vena cava syndrome (SVCS) associated with cancer (i.e malignant SVCS), even without thrombosis, but its effect on outcomes has not been reported. We aimed to determine factors and outcomes associated with thrombosis and anticoagulation in malignant SVCS. Patients with malignan...

journal_title：Journal of thrombosis and thrombolysis

authors： Ratzon R,Tamir S,Friehmann T,Livneh N,Dudnik E,Rozental A,Hamburger-Avnery O,Pereg D,Derazne E,Brenner B,Raanani P,Ten Cate H,Spectre G,Leader A

更新日期：2019-01-01 00:00:00

abstract：:Patients with Coronavirus-associated disease-2019 (COVID-19) display alterations of the hemostatic system and the presence of a prothrombotic status frequently leading to vascular complications. However, the impact of COVID-19 on platelet activity, aggregation and agglutination still needs to be clarified. We measured...

journal_title：Journal of thrombosis and thrombolysis

authors： Ruberto F,Chistolini A,Curreli M,Frati G,Marullo AGM,Biondi-Zoccai G,Mancone M,Sciarretta S,Miraldi F,Alessandri F,Ceccarelli G,Barone F,Santoro C,Alvaro D,Pugliese F,Pulcinelli FM,Policlinico Umberto I COVID-19 Group.

更新日期：2021-01-02 00:00:00

abstract：:While outpatient anticoagulation services (AMS) have existed extensively for a number of years, inpatient AMS have only recently begun to be implemented on a widespread basis. This is in direct response to anticoagulation regulations set forth by entities such as the Joint Commission (TJC) and the Centers for Medicare...

journal_title：Journal of thrombosis and thrombolysis

authors： Burnett A,D'Angio R,Earl LE,Garcia D

更新日期：2011-04-01 00:00:00

abstract：:The objective was to compare the pharmacodynamic (PD) and pharmacokinetic (PK) effects of ticagrelor with clopidogrel among subjects of Hispanic ethnicity, as the PD and PK effects of antiplatelet agents among Hispanics are not specifically known. This was a randomised, open-label, crossover PD/PK study of 40 Hispanic...

journal_title：Journal of thrombosis and thrombolysis

authors： Price MJ,Clavijo L,Angiolillo DJ,Carlson G,Caplan R,Teng R,Maya J

更新日期：2015-01-01 00:00:00

abstract：:This study was intended to evaluate the cost-effectiveness of anticoagulation clinic care and self-testing for the management of patients on chronic warfarin therapy. Using a 5-year Markov model, we evaluated the health and economic outcomes associated with each of three different anticoagulation management approaches...

journal_title：Journal of thrombosis and thrombolysis

authors： Lafata JE,Martin SA,Kaatz S,Ward RE

更新日期：2000-06-01 00:00:00

abstract：:Based on their mode of action, it is reasonable to expect that the combination therapy of aspirin and a vitamin K antagonist (VKA) may be more beneficial in preventing (athero) thrombotic complications in high-risk patients for cardiovascular events. However, there is no consensus about additional aspirin use in the m...

journal_title：Journal of thrombosis and thrombolysis

authors： Loualidi A,Bredie SH,Janssen MC

更新日期：2009-05-01 00:00:00

abstract：:Since the reports by Weismann and Tobin in 1958 and Roberts et al. in 1964 called attention to paradoxical thrombosis in patients treated with heparin, the thrombotic aspect of the heparin-induced thrombocytopenia syndrome (HIT) has been emphasized. Yet to this day, the mechanism of thrombosis associated with HIT (HIT...

journal_title：Journal of thrombosis and thrombolysis

authors： Walenga JM,Jeske WP,Messmore HL

更新日期：2000-11-01 00:00:00

abstract：:Half of patients with atrial fibrillation (AF) and elevated stroke risk do not receive anticoagulation (AC). Explanations for undertreatment may relate to provider lack of confidence with or knowledge of the CHA2DS2-VASc stroke calculator, unfamiliarity with direct oral anticoagulants (DOACs), or uncertainty about use...

journal_title：Journal of thrombosis and thrombolysis

authors： Amroze A,Mazor K,Crawford S,O'Day K,McManus DD,Kapoor A

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:The aim of our study was to determine the relation between exercise stress test and aspirin resistance in patients with stable coronary artery disease. BACKGROUND:Clinically aspirin resistance is defined as having thrombotic and embolic cardiovascular events despite regular aspirin therapy. METHODS:We stud...

journal_title：Journal of thrombosis and thrombolysis

authors： Pamukcu B,Oflaz H,Acar RD,Umman S,Koylan N,Umman B,Nisanci Y

更新日期：2005-08-01 00:00:00

abstract：:The effect of taurine on the plasma levels of L-arginine, asymmetrical dimethylarginine (ADMA) and L-arginine/ADMA ratio and nitric oxide was investigated in experimental endotoxemia. L-arginine and ADMA levels were quantified by high performance liquid chromatography with fluorescence detector. Nitric oxide level was...

journal_title：Journal of thrombosis and thrombolysis

authors： Balabanli B,Erdamar H,Türközkan N,Yaman H,Kurt Y

更新日期：2007-08-01 00:00:00

abstract：:The impact of platelet parameters on the cardiovascular risk is still debated. Gender differences in platelet volume indexes and turnover have been previously reported, potentially conditioning their role in the development of coronary artery disease (CAD). However, few studies have addressed, so far, the impact of ge...

journal_title：Journal of thrombosis and thrombolysis

authors： Negro F,Verdoia M,Tonon F,Nardin M,Kedhi E,De Luca G,Novara Atherosclerosis Study Group (NAS).

更新日期：2020-05-01 00:00:00

abstract：UNLABELLED:Coronary artery calcification may play a significant role in the pathophysiology of plaque progression and healing. We hypothesized that osteoprotegerin, an inhibitor of osteoclastogenesis, may participate in the calcification of coronary plaques or the response to injury after coronary stenting. A prospecti...

journal_title：Journal of thrombosis and thrombolysis

authors： Gogo PB Jr,Schneider DJ,Terrien EF,Sobel BE,Dauerman HL

更新日期：2006-12-01 00:00:00

abstract：:Aspirin (acetylsalicylic acid) is one of the main therapeutics in prevention of thrombo-embolic vascular events. Its efficiency is proved in the prevention of cardiovascular events. However, antiplatelet effect of aspirin is not absolute in all patients and some patients experience thrombo-embolic events despite aspir...

journal_title：Journal of thrombosis and thrombolysis

authors： Pamukcu B

更新日期：2007-06-01 00:00:00

abstract：:Kuperman et al. found that patients with anemia had a higher risk of major bleeding (RR 2.84; 95% CI 2.52-3.39) in RIETE database. Anemia appeared to be an independent predictive factor for major bleeding [hazard ratio (HR) 1.95; 95% CI 1.72-2.20] in this registry. Unfortunately, selection bias due to enrolled patient...

journal_title：Journal of thrombosis and thrombolysis

authors： Gaboreau Y,Zenatti N,Vermorel C,Imbert P,Bosson JL,Pernod G

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Impairment of coronary microvascular perfusion is common among patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). Cardiovascular magnetic resonance imaging (CMR) can identify microvascular obstruction (MO) following reperfusion of S...

journal_title：Journal of thrombosis and thrombolysis

authors： Appelbaum E,Kirtane AJ,Clark A,Pride YB,Gelfand EV,Harrigan CJ,Kissinger KV,Manning WJ,Gibson CM

更新日期：2009-02-01 00:00:00

abstract：:The objective of this study was to determine if aspirin users presenting with acute coronary syndromes are at higher risk for subsequent clinical events. In a trial evaluating combination antithrombotic therapy in resting angina or non-Q-wave myocardial infarction (MI), patients were prospectively dichotomized on admi...

journal_title：Journal of thrombosis and thrombolysis

authors： Cohen M,Adams PC,McBride R,Blanke H,Fuster V V

更新日期：1997-01-01 00:00:00

abstract：:Erythropoietin (EPO) was hypothesized to mitigate reperfusion injury, in part via mobilization of endothelial progenitor cells (EPCs). The REVEAL trial found no reduction in infarct size with a single dose of EPO (60,000 U) in patients with ST-segment elevation myocardial infarction. In a substudy, we aimed to determi...

journal_title：Journal of thrombosis and thrombolysis

authors： Povsic TJ,Najjar SS,Prather K,Zhou J,Adams SD,Zavodni KL,Kelly F,Melton LG,Hasselblad V,Heitner JF,Raman SV,Barsness GW,Patel MR,Kim RJ,Lakatta EG,Harrington RA,Rao SV

更新日期：2013-11-01 00:00:00

abstract：:Anticoagulation for the prevention of stroke is an important aspect of the management of atrial fibrillation. Novel anticoagulants including oral factor Xa inhibitors rivaroxaban and apixaban and the direct thrombin inhibitor dabigatran have emerged as important therapeutic treatment options for prevention of stroke i...

journal_title：Journal of thrombosis and thrombolysis

authors： DeWald TA,Becker RC

更新日期：2014-01-01 00:00:00

abstract：:We sought to determine the diagnostic value of a D-dimer test for myocardial infarction (MI). The prospective cohort study was carried in the ED of a university hospital. All included patients were tested for D-dimer and cardiac troponin I (cTnI) on ED admission and additional cTnI 6 h later. AMI was retrospectively c...

journal_title：Journal of thrombosis and thrombolysis

authors： Chang SS,Lee SH,Wu JY,Ning HC,Chiu TF,Wang FL,Chen JH,Li CH,Lee CC,Chan RC

更新日期：2010-11-01 00:00:00

abstract：:The initial treatment of acute venous thrombosis using low-molecular-weight heparin (LMWH) in the outpatient setting has been shown to be feasible, effective, and safe for selected patients when compared with in-hospital treatment using continuous intravenous heparin. There will always be a significant population of p...

journal_title：Journal of thrombosis and thrombolysis

authors： Pineo GF,Hull RD

更新日期：1998-01-01 00:00:00

abstract：:Early rapid platelet inhibition with abciximab before primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) is suggested as beneficial. In previous studies on early abciximab administration clopidogrel was administered in cathlab in low loading dose. We investigated t...

journal_title：Journal of thrombosis and thrombolysis

authors： Dudek D,Rakowski T,Bartus S,Giszterowicz D,Dobrowolski W,Zmudka K,Zalewski J,Ochala A,Wieja P,Janus B,Dziewierz A,Legutko J,Bryniarski L,Dubiel JS

更新日期：2010-10-01 00:00:00

abstract：:Intravenous (IV) thrombolysis is the treatment in ischemic stroke, but only the minority of patients receive this medication. The primary objective of this study was to explore the reasons associated with the decision not to offer IV thrombolysis to stroke patients admitted to the Stroke Unit (SU). We conducted a retr...

journal_title：Journal of thrombosis and thrombolysis

authors： Cappellari M,Bosco M,Forlivesi S,Tomelleri G,Micheletti N,Carletti M,Bovi P

更新日期：2016-11-01 00:00:00