Abstract:
:A new glycosyl inositolphosphoceramide-type ganglioside, CSP2, was obtained from the polar lipid fraction of the chloroform/methanol extract of the feather star Comanthina schlegeli together with a known same type of ganglioside CJP2. The structure of this ganglioside has been determined on the basis of chemical and spectroscopic evidence to be 9-O-methyl-(N-acetyl-alpha-D-neuraminosyl)-(2-->3)-inositolphosphoceramide, which contains C(16)-sphingosine and C(22:0)-, C(24:0)-fatty acid as major component. This is the first report on the isolation and structural elucidation of a glycosyl inositolphosphoceramide-type ganglioside possessing N-acetyl-neuraminic acid (NeuAc) residue.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Inagaki M,Shiizaki M,Hiwatashi T,Miyamoto T,Higuchi Rdoi
10.1248/cpb.55.1649subject
Has Abstractpub_date
2007-11-01 00:00:00pages
1649-51issue
11eissn
0009-2363issn
1347-5223pii
JST.JSTAGE/cpb/55.1649journal_volume
55pub_type
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