Abstract:
:The purpose of this study is to evaluate the efficacy of intraoperative radiation therapy (IORT) and the problem of securing the IORT field in advanced pediatric neuroblastoma. Between 1996 and 2005, 12 children received IORT for advanced pediatric neuroblastoma patients. Electron beam energies ranged from 10 to 12 MeV and median dose was 10 Gy (8-12 Gy). All of them had surgery with IORT against the primary tumor site and the abdominal aorta surroundings. A gross total resection (GTR) was achieved in 10 patients and subtotal resection (STR) was two patients. All of 12 patients were classified as high risk. Nine patients were alive 17-120 (mean 48 months) after diagnosis. Local tumor control was achieved in 100% of patients, of whom one experienced local recurrence outside the IORT field. At the operation, it was difficult to secure the IORT field because of the angle of the radiation cylinder in three patients. One of the three of these patients experienced local recurrence outside of the IORT field in the upper side of superior mesenteric artery and two of three patients had an external beam radiation after surgery, and there was no local recurrence. One patient had a postoperative ileus, and one patient had transient diarrhea and hydronephrosis. For advanced neuroblastoma patients, IORT produced excellent local control after surgery. However, there is a problem of securing the IORT field. For local control, it is necessary to add an external beam radiation after IORT when it is difficult to secure the IORT field.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Sugito K,Kusafuka T,Hoshino M,Inoue M,Goto H,Ikeda T,Hagiwara N,Koshinaga T,Fukuzawa M,Nakamura M,Shichino H,Chin M,Mugishima H,Saito T,Tanaka Ydoi
10.1007/s00383-007-2065-9subject
Has Abstractpub_date
2007-12-01 00:00:00pages
1203-7issue
12eissn
0179-0358issn
1437-9813journal_volume
23pub_type
杂志文章abstract::Congenital lung lesions are diagnosed antenatally in the majority of cases. Postnatal management includes chest radiography and CT-scanning, followed by either surgical resection or CT surveillance. Pre-operatively, lesions are often "labelled" as CCAM (and the Stocker classification incorrectly applied), sequestratio...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2201-1
更新日期:2008-09-01 00:00:00
abstract::Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general surgery, however, it has not completely replaced the standard open operative procedures in pediatric oncology. The aim of this study was to evaluate the host relationship following MIS in a murine model of retroperitoneal neurob...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050271
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Retinoids are essential for fetal and lung development. Beta-carotene(BC) is the main dietary retinoid source and beta-carotene-15,15'-oxygenase-1 and 2 (Bcmo1,2) is the primary enzyme generating retinoid from BC in adult mammalian tissues. Placenta has a major role in the retinol homeostasis in fetal life: ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3621-8
更新日期:2015-01-01 00:00:00
abstract::Inflammatory bowel disease (IBD) in children can cause significant impairment in linear growth, and delay in pubertal onset. The aim of this study was to assess the impact of surgery on linear growth in children with Crohn's disease (CD) who were resistant to medical therapy, and had documented evidence of growth impa...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1664-1
更新日期:2006-04-01 00:00:00
abstract::Hirschsprung disease (HSCR) is a fairly well understood congenital, genetically based functional obstruction due to the congenital absence of ganglion cells in the distal bowel. However, although over 90% of Hirschsprung cases conform to the normally accepted histological diagnostic criteria, it has become increasingl...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-016-4038-3
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:The optimal management of simple hepatic cysts (SHCs) remains controversial. A retrospective review was carried out to evaluate the clinical presentation and surgical consideration of children with SHCs and outcome of management at our institution. METHODS:We performed a retrospective review of all patients di...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3509-7
更新日期:2014-06-01 00:00:00
abstract:INTRODUCTION:This review aims to (1) assess the breadth of pediatric orthopaedic research in low- and middle-income countries (LMICs) and (2) determine the impact of academic collaboration (an LMIC and a non-LMIC investigator) in published LMIC research. METHODS:Pediatric orthopaedic clinical studies conducted in LMIC...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-018-4412-4
更新日期:2019-03-01 00:00:00
abstract::Pseudoexstrophy is a rare variant of the exstrophy/epispadias complex, comprised of the musculoskeletal defects of classic exstrophy but with an intact bladder and urethra. We present a case of a neonate with left-sided gastroschisis and pseudoexstrophy, the first reported combination of these two anomalies. The anoma...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1217-4
更新日期:2004-07-01 00:00:00
abstract:AIM OF THE STUDY:Liver retraction during laparoscopic fundoplication is important for obtaining an optimal space. Several methods have been developed, but the risks and benefits are unclear. We compared three different approaches and evaluated their safety and utility. METHODS:Forty-three neurologically impaired patie...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04646-8
更新日期:2020-05-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-019-04440-1
更新日期:2019-04-01 00:00:00
abstract::Minor degrees of exomphalos have been known to be associated with vitellointestinal duct anomalies. The most frequent association is Meckel's diverticulum. It is unusual for a fistula to be communicating directly with the exomphalos sac. We report five neonates that presented with a fistula on the exomphalos sac over ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-006-1699-3
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Variation exists in the diagnostic testing for gastroesophageal reflux (GER) in infants and in the application of surgical therapy. There has been an increase in antireflux surgery (ARS) since the development of laparoscopy but the outcomes in high-risk infants is unclear. This study examines the results of ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4281-x
更新日期:2018-07-01 00:00:00
abstract::Perineal-mound (PMD) and genital-fold defects cause anorectal malformations (ARM) in both sexes. They are common in females and usually present as a low anomaly (except rectovestibular fistula). They are rare in males and present as an intermediate anomaly. A common embryological explanation for these defects with var...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s003830050562
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine the incidence of gastroschisis-related complications (GRCs) after closure of the abdominal wall defect, with a focus on frequency, type and timing of required surgical interventions, and to identify the impact of these on further outcome. METHODS:All gastroschisis patient...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3500-3
更新日期:2014-06-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-010-2712-4
更新日期:2011-01-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00174584
更新日期:1996-12-01 00:00:00
abstract:AIM:The aim of this study was to examine the relationship between birth weight, pulmonary artery (PA) size, and outcome in congenital diaphragmatic hernia (CDH) to establish if PA size has prognostic value. METHODS:The subjects for this study were 39 consecutive left-sided CDH patients treated at our institution accor...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2899-z
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:The clinical application of autologous tissue-engineered skin analogs is an important strategy to cover large skin defects. Investigating biological dynamics, such as reinnervation after transplantation, is essential to improve the quality of such skin analogs. Previously, we have examined that our skin substit...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3978-y
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is considered to benefit the patients with vesico-prostatic fistula. The aim of this study is to present the details of our LAARP technique for improving the short- and long-term outcomes in the patients with high and intermediate types of anorectal malformations (AR...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04614-x
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-010-2736-9
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050438
更新日期:1998-11-01 00:00:00
abstract::A retrospective study of all cases (n = 21) of congenital lobar emphysema (CLE) treated at the Royal Hospital, Muscat, from September 1988 to August 1999 was performed. The presentation, diagnosis, treatment, and outcome are reviewed. All 21 patients were nonwhite. Thirteen had left-upper-lobe, 7 right-middle-lobe, an...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000506
更新日期:2001-03-01 00:00:00
abstract:AIM:An experimental study was performed to investigate the efficacy of colchicine in the prevention of fibrosis in the alkaline burn of the esophagus in rats. METHOD:A standard esophageal alkaline burn was produced by the application of 37.5% NaOH for a period of 90 s to the distal esophagus followed by a water rinse....
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1644-5
更新日期:2006-04-01 00:00:00
abstract::Parathyroid carcinoma is unusual and its intrathyroidal variant is extremely rare. Therefore, few cases have been reported to describe a case of parathyroid carcinoma located inside the thyroid gland. The case corresponds to a 14-year-old girl who came to the office with a severe osteoarticular disease, depression, ca...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2904-6
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:Rapid assessment of volume status in children is often difficult. The purpose of this study was to evaluate the feasibility of surgeon-performed ultrasound to assess volume status in patients with hypertrophic pyloric stenosis. METHODS:Ultrasounds were performed on admission and before operation. The diameters...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3798-5
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:The use of general anesthesia in young children has come under increasing scrutiny due to its potential long-term neurotoxic effects. Meanwhile, regional anesthesia for surgical procedures in neonates has many advantages, including preservation of respiratory status and faster return to feeding. We describe the...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-4027-6
更新日期:2017-03-01 00:00:00
abstract::Desmoplastic small round cell tumour (DSRCT) is an extremely rare neoplasm. Adolescent males and young adults are most frequently affected. It is highly malignant, with only 29% of patients surviving up to 3 years. This paper documents two cases, one of which, at 4 years old, is the second youngest case documented. Ca...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1401-1
更新日期:2005-04-01 00:00:00
abstract::The activity of phospholipase A2 (PLA2) is elevated in the intestinal epithelia of patients with inflammatory bowel disease (IBD). We recently reported that PLA2 mediates hydrolysis of phosphatidylcholine (PC) to lysophosphatidylcholine (L-PC) when both are applied to the apical surface of cultured EC monolayers, resu...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830100592
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:The RAS association domain family protein 1 (RASSF1A) is known to be frequently inactivated by promoter hypermethylation in cancers. This study investigated the association of RASSF1A methylation with clinical outcomes in hepatoblastoma patients and whether it is correlated with the histological phenotype of he...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3371-z
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:The surgical treatment of children with H-fistula is one of the understudied problems of the present day, especially regarding its high rates of complications. The surgical technique of bringing down the anterior wall of rectum in clinical practice allows us in reducing the rate of H-fistula recurrences. The re...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2234-5
更新日期:2008-11-01 00:00:00