Humoral immunity 5 years after booster immunization with an adolescent and adult formulation combined tetanus, diphtheria, and 5-component acellular pertussis vaccine.

abstract：:Vaccines that could protect humans against the highly lethal Marburg and Ebola viruses have eluded scientists for decades. Classical approaches have been generally unsuccessful for Marburg and Ebola viruses and pose enormous safety concerns as well. Modern approaches, in particular those using vector-based approaches ...

journal_title：Vaccine

authors： Reed DS,Mohamadzadeh M

更新日期：2007-03-01 00:00:00

abstract：:Dynamic studies of influenza virus infection in the live cells are limited because of the lack of appropriate methods for non-invasive detection of the viral components. Using the split-GFP strategy, we have recently developed and characterized an unimpaired recombinant influenza A virus encoding a tagged PB2 subunit ...

journal_title：Vaccine

authors： Avilov SV,Moisy D,Naffakh N,Cusack S

更新日期：2012-12-07 00:00:00

abstract：:Wildebeest-associated malignant catarrhal fever (WA-MCF), a fatal disease of cattle caused by alcelaphine herpesvirus 1 (AlHV-1), is one of the most important seasonal diseases of cattle in wildebeest endemic areas, with annual incidence reaching 10%. Here we report efficacy of over 80% for a vaccine based on the atte...

journal_title：Vaccine

authors： Cook E,Russell G,Grant D,Mutisya C,Omoto L,Dobson E,Lankester F,Nene V

更新日期：2019-09-20 00:00:00

abstract：:We have compared two types of plasmids for DNA immunization against HTLV-I envelope glycoproteins. One type of plasmid contains the coding DNA of the complete envelope gene of HTLV-I under the control of the CMV promoter with (CMVenvLTR) or without (CMVenv) the tax/rex genes. The second type contains the coding DNA of...

journal_title：Vaccine

authors： Armand MA,Grange MP,Paulin D,Desgranges C

更新日期：2000-04-28 00:00:00

abstract：:Enteroviruses elicit protective mucosal immune responses that could be harnessed as part of a strategy to prevent sexual transmission of the human immunodeficiency virus-1 (HIV-1). We report the construction of replication-competent recombinant vectors of coxsackievirus B3 (CVB3) that express one or more portions of t...

journal_title：Vaccine

authors： Miller JP,Geng Y,Ng HL,Yang OO,Krogstad P

更新日期：2009-06-19 00:00:00

abstract：:Classical swine fever virus (CSFV) causes significant losses in pig industry in many countries in Asia and Europe. The E2 glycoprotein of CSFV is the main target for neutralizing antibodies. Recently, the replicon of alphaviruses, such as Semliki Forest virus (SFV), has been developed as replicative expression vectors...

journal_title：Vaccine

authors： Li N,Qiu HJ,Zhao JJ,Li Y,Wang MJ,Lu BW,Han CG,Hou Q,Wang ZH,Gao H,Peng WP,Li GX,Zhu QH,Tong GZ

更新日期：2007-04-12 00:00:00

abstract：INTRODUCTION:In 2005, in Finland, the whole-cell pertussis vaccine was replaced by acellular given at 3-5-12months, and boosters at 4 and 11-15years of age. From July 2012, military conscripts have been offered a pertussis booster dose. Conscription is mandatory for Finnish men, and >95% were 19-21years old when enroll...

journal_title：Vaccine

authors： Zöldi V,Sane J,Nohynek H,Virkki M,Hannila-Handelberg T,Mertsola J

更新日期：2017-09-18 00:00:00

abstract：:Plasmodium falciparum Pfs25 antigen, expressed on the surface of zygotes and ookinetes, is one of the leading targets for the development of a malaria transmission-blocking vaccine (TBV). Our laboratory has been evaluating DNA plasmid based Pfs25 vaccine in mice and non-human primates. Previously, we established that ...

journal_title：Vaccine

authors： Kumar R,Nyakundi R,Kariuki T,Ozwara H,Nyamongo O,Mlambo G,Ellefsen B,Hannaman D,Kumar N

更新日期：2013-06-28 00:00:00

abstract：:The current human whole-cell vaccine is ineffective against pneumonic plague caused by typical F1 capsule positive (F1+) strains of Yersinia pestis. The authors found this vaccine to also be ineffective against F1-negative (F1-) Y. pestis strains, which have been isolated from a human case and from rodents. For these ...

journal_title：Vaccine

authors： Heath DG,Anderson GW Jr,Mauro JM,Welkos SL,Andrews GP,Adamovicz J,Friedlander AM

更新日期：1998-07-01 00:00:00

abstract：:Cattle produce specific serum antibody mainly of the IgG1 isotype in response to infection with the liver fluke, Fasciola hepatica. In these animals a positive correlation between fluke-specific serum IgG1 levels and fluke-burden in non-immunized infected animals was observed. In contrast, immunization of cattle with ...

journal_title：Vaccine

authors： Mulcahy G,O'Connor F,McGonigle S,Dowd A,Clery DG,Andrews SJ,Dalton JP

更新日期：1998-05-01 00:00:00

abstract：:Brucellosis is one of the most prevalent zoonotic diseases of worldwide distribution caused by the infection of genus Brucella. Live attenuated vaccines such as B. abortus S19, B. abortus RB51 and B. melitensis Rev1 are found most effective against brucellosis infection in animals, contriving a number of serious side ...

journal_title：Vaccine

authors： Vrushabhendrappa,Singh AK,Balakrishna K,Sripathy MH,Batra HV

更新日期：2014-09-29 00:00:00

abstract：:In Japan, trivalent inactivated influenza vaccine is the only approved influenza vaccine. It is typically administrated by hypodermic injection, and children under 13 years of age are recommended to be vaccinated two times during each winter season. Live-attenuated influenza vaccine (LAIV) is administered by a thimero...

journal_title：Vaccine

authors： Shono A,Kondo M

更新日期：2014-09-03 00:00:00

abstract：:In clinical trials recombinant-modified vaccinia virus Ankara expressing the Mycobacterium tuberculosis antigen 85A (MVA85A) induces approximately 10 times more effector T cells than any other recombinant MVA vaccine. We have found that in BCG primed subjects MVA85A vaccination reduces transforming growth factor beta ...

journal_title：Vaccine

authors： Fletcher HA,Pathan AA,Berthoud TK,Dunachie SJ,Whelan KT,Alder NC,Sander CR,Hill AV,McShane H

更新日期：2008-09-26 00:00:00

abstract：INTRODUCTION:Streptococcus pneumoniae is a capsulated bacterium that can cause severe infection in patients with thalassemia major, particularly those who have undergone splenectomy. The absence of the spleen as well as zinc deficiency in splenectomized patients with thalassemia major increases the possibility of devel...

journal_title：Vaccine

authors： Sari TT,Akib AAP,Gatot D,Roswita Harahap A,Bardosono S,Hadinegoro SRS

更新日期：2017-08-16 00:00:00

abstract：:To identify Mycobacterium tuberculosis (Mtb) antigens as candidates for a subunit vaccine against tuberculosis (TB), we have employed a CD4+ T-cell expression screening method. Mtb-specific CD4+ T-cell lines from nine healthy PPD positive donors were stimulated with different antigenic substrates including autologous ...

journal_title：Vaccine

authors： Coler RN,Dillon DC,Skeiky YA,Kahn M,Orme IM,Lobet Y,Reed SG,Alderson MR

更新日期：2009-01-07 00:00:00

abstract：:Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and the Arabian Peninsula that affects sheep, cattle, goats, camels, and humans. Effective vaccination of susceptible ruminants is important for the prevention of RVF outbreaks. Live-attenuated RVF vaccines are in general highly immunogenic...

journal_title：Vaccine

authors： Ly HJ,Nishiyama S,Lokugamage N,Smith JK,Zhang L,Perez D,Juelich TL,Freiberg AN,Ikegami T

更新日期：2017-12-04 00:00:00

abstract：:With declining influenza vaccine coverage in the elderly in recent years in France, we aimed at assessing the benefits of seasonal influenza vaccination, based on available data for observed mortality, vaccine coverage and vaccine effectiveness. To estimate the annual number of deaths avoided by vaccination in the peo...

journal_title：Vaccine

authors： Bonmarin I,Belchior E,Lévy-Bruhl D

更新日期：2015-02-25 00:00:00

abstract：:The most common preventative measure against mumps is vaccination with mumps vaccine. In most parts of the world, mumps vaccine is routinely delivered through live attenuated Measles-Mumps-Rubella (MMR) vaccine. In Japan, receiving mumps vaccine is voluntary and vaccine uptake rate is less than 30%. The introduction o...

journal_title：Vaccine

authors： Hoshi SL,Kondo M,Okubo I

更新日期：2014-07-16 00:00:00

abstract：:Studies have demonstrated that lipid rafts ultimately regulate the endocytosis of anthrax toxin via clathrin dependent pathway. Interestingly, GPI-anchored protein rich rafts have also been shown to be transported down to the endocytic pathway to reducing late endosomes. Taking advantage of this parallelism, we tried ...

journal_title：Vaccine

authors： Midha S,Bhatnagar R

更新日期：2009-03-10 00:00:00

abstract：:Formalin-killed Streptococcus difficile strains used as vaccines delivered intraperitoneally were able to protect tilapia against a challenge of 100 LD50. The protection obtained was not strain specific. A vaccine based on an S. difficile extract containing 50% protein conjugated to alum also protected tilapia challen...

journal_title：Vaccine

authors： Eldar A,Shapiro O,Bejerano Y,Bercovier H

更新日期：1995-06-01 00:00:00

abstract：:This study aimed to evaluate the durability of the immunogenicity of MVA85A beyond infancy. Participants in an immunogenicity study of MVA85A administered at age of 4 months had additional evaluation 14 months after initial vaccination for IFN-γ ELISPOT responses to Ag85A peptide and ESAT6/CFP-10 and tuberculin skin t...

journal_title：Vaccine

authors： Odutola AA,Owolabi OA,Owiafe PK,McShane H,Ota MO

更新日期：2012-08-17 00:00:00

abstract：:The modular binding sites on the influenza A(H3N2) hemagglutinin protein are under significant pressure to acquire mutations in order to evade human antibody recognition. Analysis of these hemagglutinin epitopes in the strains circulating during 2017/18 and early 2018/19 identified the emergence of a new antigenic clu...

journal_title：Vaccine

authors： Bonomo ME,Kim RY,Deem MW

更新日期：2019-05-27 00:00:00

abstract：:Varicella vaccine has been licensed in Canada since December 1998 but not provided free in all provinces. Through a cross-sectional telephone survey to a random sample of parents, we assessed factors associated with varicella vaccine uptake in the absence of public funding. Parents of children aged 2-3 years (Group I)...

journal_title：Vaccine

authors： Gustafson R,Skowronski DM

更新日期：2005-05-20 00:00:00

abstract：:A hybrid protein [Met-Ala-(His)(6) OprF(190-342)-OprI(21-83)] consisting of the mature outer membrane protein I (OprI) and amino acids 190-342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni(2+) chelate-affinity chromatography. After several studies in healthy volunteers, as well...

journal_title：Vaccine

authors： Larbig M,Mansouri E,Freihorst J,Tümmler B,Köhler G,Domdey H,Knapp B,Hungerer KD,Hundt E,Gabelsberger J,von Specht BU

更新日期：2001-03-21 00:00:00

abstract：:Because of the serious economic and medical consequences of brucellosis, efforts are to prevent infection of domestic animals through vaccines. Many disadvantages are associated with the current Brucella melitensis Rev.1 vaccine prompting development of alternative vaccines and delivery. Escherichia coli (DH5α) was en...

journal_title：Vaccine

authors： Gupta VK,Radhakrishnan G,Harms J,Splitter G

更新日期：2012-06-08 00:00:00

abstract：:The rectum as an effective site for induction of systemic and local immunity has received little attention. Rectal immunization with microspheres-containing ovalbumin (MS-OVA) was tested for its ability to elicit systemic and mucosal immune responses. Rectal immunization with MS-OVA enhanced both Th2 dominant OVA-spec...

journal_title：Vaccine

authors： Nakase H,Okazaki K,Tabata Y,Uchida K,Uose S,Ohana M,Nishi T,Watanabe T,Matsuura M,Hisatsune H,Matsumura K,Itoh T,Kawanami C,Chiba T

更新日期：2001-11-12 00:00:00

abstract：:Cholera toxin B subunit (CTB) and Escherichia coli heat-labile toxin (LTB) (2 micrograms), each supplemented with a trace amount of cholera toxin (CT) (0.02-20 ng), were examined for the adjuvant effect on antibody (Ab) response against influenza inactivated HA (haemagglutinin) vaccine in Balb/c mice. Each mouse recei...

journal_title：Vaccine

authors： Tamura S,Yamanaka A,Shimohara M,Tomita T,Komase K,Tsuda Y,Suzuki Y,Nagamine T,Kawahara K,Danbara H

更新日期：1994-04-01 00:00:00

abstract：:The first population-based survey to determine predictors of influenza vaccination among children in a major metropolitan city with access to publicly funded health care and a universal influenza immunization program (UIIP). Previously collected demographic and health related data from 5619 school children aged 5-9 in...

journal_title：Vaccine

authors： Foty RG,Guttmann A,Kwong JC,Maaten S,Manuel D,Stieb DM,Dell SD

更新日期：2010-09-07 00:00:00

abstract：:Intranasal inactivated influenza vaccines have the advantage over parenteral vaccines in that they are not associated with the pain of an injection. However, they would be most useful if they were available for all age groups, including high-risk groups, and also would provide cross-protection against variant virus st...

journal_title：Vaccine

authors： Tamura S

更新日期：2010-08-31 00:00:00

abstract：:Vaccination is the best available measure of limiting the impact of the next influenza pandemic. Ideally, a candidate pandemic influenza vaccine should be easy to administer and should elicit strong mucosal and systemic immune responses. Production of influenza subunit antigen in transient plant expression systems is ...

journal_title：Vaccine

authors： Madhun AS,Haaheim LR,Nøstbakken JK,Ebensen T,Chichester J,Yusibov V,Guzman CA,Cox RJ

更新日期：2011-07-12 00:00:00