[Cytochrom P-450. Its value in toxicology. I. Physicochemical and biochemical properties].

Abstract:

:We present the distribution of cytochrome P450, the terminal oxidase of the microsomal drug-metabolizing system among the different species, organs, and its subcellular localization. Physicochemical properties, and more specially spectral properties, of this hemoprotein are reviewed. We also described the two microsomal electron transport chains and the hypothetical cyclic oxidoreduction mechanism of cytochrome P450 in the hydroxylation reactions.

journal_name

Ann Biol Clin (Paris)

authors

Boudene C,Boisset M

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

399-410

issue

6

eissn

0003-3898

issn

1950-6112

journal_volume

33

pub_type

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