The Heart and APS.

Abstract:

:The heart is a target organ in antiphospholipid syndrome (APS). Endocardial disease, intracardiac thrombosis, myocardial involvement including coronary heart disease and microvascular thrombosis, as well as pulmonary hypertension have all been described in APS patients. Valvular involvement is the most common manifestation with a prevalence of 82% detected by transesophageal echocardiography. Symmetrical, nodular thickening of the mitral and/or aortic valves is characteristic. Anticoagulant/antiplatelet treatment is ineffective in terms of valvular lesion regression. Some patients require cardiac valve replacement. However, patients with APS have shown an increased perioperative morbidity and mortality. Intracardiac thrombosis, although a rare complication, can cause pulmonary and systemic emboli. Differential diagnosis with myxoma may be very difficult.

authors

Amigo MC

doi

10.1007/s12016-007-0013-z

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

178-83

issue

2

eissn

1080-0549

issn

1559-0267

pii

CRIAI:32:2:178

journal_volume

32

pub_type

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