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Design of a pyrene-containing fluorescence probe for labeling of RNA poly(A) tracts.

Abstract：

:A labeling probe containing a pyrenecarboxamide-tethered modified DNA base, (Py)U, has been developed for fluorometric detection of RNA poly(A) tracts, in which the fluorescence emission intensity was controlled by the microstructural change around (Py)U caused by binding with the target RNA.

journal_name

Bioorg Med Chem

journal_title

Bioorganic & medicinal chemistry

authors

Tanaka K,Okamoto A

doi

10.1016/j.bmc.2007.09.024

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

400-4

issue

1

eissn

0968-0896

issn

1464-3391

pii

S0968-0896(07)00810-3

journal_volume

16

pub_type

杂志文章

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