Abstract：
BACKGROUND:Port wine stains (PWS) affect 0.3-0.5% of both sexes of newborns, usually occurring on the face. OBJECTIVE:To document safety and effectiveness of cryogen spray cooled, pulsed-dye laser at higher fluences than previously used to lighten facial PWS in infants < or =6 months, and establish that frequent treatment early in life yields better clearance than if delayed until later in life. MATERIALS AND METHODS:Forty-nine infants who had been treated with pulsed-dye laser treatments for facial PWS at < or =6 months were identified by case review of photographs, age, sex, PWS severity score prior to laser treatment, number of treatments, and improvement following laser therapy. RESULTS:Patients averaged 9.3 (range 2-16) treatments at 4-6 week intervals at 7.75-9.5 J/cm(2). Average surface area treated was 24.0% with 88.6% average clearance after 1 year. Average clearance was 90.7% for lesions covering <20% surface area and 85.6% for lesions > or =20%. Location (V1, V2, V3, eye, and/or scalp), treated surface area, treatment number, and fluence predicted clearance. Average clearance for sole involvement of V1 was highest (at 93.8%), followed by V2 (at 91.1%), V3 (at 84.3%), V1/V2 (at 83.7%), V1/V2/V3 (at 81.0%), periocular (at 88.6%), and scalp (at 89.9%). All patients tolerated the higher treatment fluences without atrophy or scarring. DISCUSSION/CONCLUSIONS:Frequent, high energy pulsed-dye laser treatments are safe and highly effective in improving facial PWS in infants < or =6 months of age. Patients with PWS should be referred for pulsed-dye laser treatment during early infancy.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Chapas AM,Eickhorst K,Geronemus RGdoi
10.1002/lsm.20529subject
Has Abstractpub_date
2007-08-01 00:00:00pages
563-8issue
7eissn
0196-8092issn
1096-9101journal_volume
39pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:Fifty percent human albumin solder significantly improves weld strength when compared to lower concentrations [Wright et al., ASLMS meeting, April, 1995]. We developed a method for preparing 50% human albumin that may be considered compatible for clinical applications. STUDY DESIGN/MATERIALS A...
journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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更新日期：2002-01-01 00:00:00
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journal_title：Lasers in surgery and medicine
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journal_title：Lasers in surgery and medicine
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