Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia.

Abstract:

:The current study evaluated under double-blind placebo-controlled conditions, the safety and efficacy of 400 mg pramiracetam sulphate TID in treating memory and other cognitive problems of males who have sustained brain injuries. The results of the study indicate that subject performance in measures of memory, especially delayed recall, evidenced clinically significant improvements after the administration of pramiracetam sulphate as compared to placebo. This improvement was maintained during an 18-month open-trial period on the medication as well as during a 1-month follow-up period after the pramiracetam was discontinued.

journal_name

Brain Inj

journal_title

Brain injury

authors

McLean A Jr,Cardenas DD,Burgess D,Gamzu E

doi

10.3109/02699059109008110

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

375-80

issue

4

eissn

0269-9052

issn

1362-301X

journal_volume

5

pub_type

临床试验,杂志文章,随机对照试验
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