Abstract:
:A series of 1,3-benzothiazol-2-yl benzamides (11-30) were prepared in satisfactory yield and evaluated for their anticonvulsant, neurotoxicity, CNS depressant study and other toxicity studies. All the synthesized compounds were in good agreement with elemental and spectral data. Majority of the compounds were active in MES and scPTZ screen and showed the decrease in the immobility time. None of the compounds had shown neurotoxicity or liver toxicity.
journal_name
Eur J Med Chemjournal_title
European journal of medicinal chemistryauthors
Rana A,Siddiqui N,Khan SA,Ehtaishamul Haque S,Bhat MAdoi
10.1016/j.ejmech.2007.07.008subject
Has Abstractpub_date
2008-05-01 00:00:00pages
1114-22issue
5eissn
0223-5234issn
1768-3254pii
S0223-5234(07)00298-Xjournal_volume
43pub_type
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