Abstract：
:B-type natriuretic peptide (BNP) reflects volume overload on left ventricle and pulmonary hypertension (PH) in patients with ventricular septal defect (VSD). Pulmonary vascular resistance (PVR) has been reported to correlate positively with BNP in VSD patients with various degrees of PH. We aimed to investigate the relationship between PVR and BNP in VSD patients with severe PH. We examined 24 subjects with VSD concomitant severe PH aged from 2 months to 17 years (median: 4 months). The ratio of pulmonary to systemic pressure (Pp/Ps), the ratio of pulmonary to systemic flow (Qp/Qs), the ratio of pulmonary to systemic resistance (Rp/Rs), and PVR were determined by cardiac catheterization. PVR and Rp/Rs ranged from 1.6 to 15.5 (mean: 5.7 +/- 3.9) Wood unit . m(2) and 0.1 to 0.8 (mean: 0.4 +/- 0.2), respectively. BNP ranged from 5.5 to 69 (mean: 31 +/- 19) pg/ml. Negative correlations were observed between BNP and PVR (r = -0.56, p = 0.004) and BNP and Rp/Rs (r = -0.51, p = 0.01). BNP was significantly lower (<10 pg/ml) in VSD patients with Eisenmenger physiology as compared with the others (p = 0.003). We should draw attention to evaluate BNP values in VSD patients with severe PH.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Toyono M,Harada K,Tamura M,Aoki-Okazaki M,Shimada S,Oyamada J,Takada Gdoi
10.1007/s00246-007-9037-7subject
Has Abstractpub_date
2008-01-01 00:00:00pages
65-9issue
1eissn
0172-0643issn
1432-1971journal_volume
29pub_type
杂志文章abstract：:Noninvasive Doppler-derived cardiac output was measured with the pulsed Doppler method in 22 healthy newborns during their first four days of life. Maximal blood flow velocity in the aorta was measured with the Doppler ultrasound method. The mean Doppler-derived cardiac output was 273 +/- 59 ml/min/kg. Ductal left-to-...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02083704
更新日期：1988-01-01 00:00:00
abstract：:A case report of a neonate with cardiac tumors in association with tuberous sclerosis is presented. The rare complication of pulmonary embolism and its successful treatment by anticoagulation and thrombolytic therapy is described. The treatment of these cardiac tumors is conservative, because the tumors regress sponta...
journal_title：Pediatric cardiology
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doi：10.1007/s002460010247
更新日期：2001-07-01 00:00:00
abstract：:An 11 day-old female infant underwent resection of a mass in the subaortic region secondary to critical aortic stenosis. At 3 months of age, recurrent severe left-ventricular outflow obstruction (LVOT) in the setting of heart failure prompted redo surgery, and the resected mass revealed an intracardiac foregut cyst, w...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0623-y
更新日期：2013-01-01 00:00:00
abstract：:Since its first description in Japan 30 years ago, Kawasaki disease has been reported worldwide. Although an infectious etiology is suspected based on the epidemiology and clinical features, a causative agent has not been identified. The majority of the morbidity and mortality associated with this condition is attribu...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s002469900436
更新日期：1999-05-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-002-0137-0
更新日期：2003-01-01 00:00:00
abstract：:Numerous RNA-binding proteins (RBPs) are expressed in the heart, and mutations in several RBPs have been implicated in cardiovascular disease through genetic associations, animal modeling, and mechanistic studies. However, the functions of many more cardiac RBPs, and their relevance to disease states, remain to be elu...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
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abstract：:Maintaining patency of the ductus arteriosus pending surgical intervention can be critical to the survival of the neonate with ductal dependent congenital heart disease. Spontaneously delayed ductal closure has been observed clinically and experimentally in newborns with critical pulmonic stenosis. Infants with ductal...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02263445
更新日期：1987-01-01 00:00:00
abstract：:We aimed to investigate the complications after epicardial pacemaker (PM) implantation in neonates and infants and their relationship with factors such as device size and patient size. Between May 2010 and July 2018, 55 patients under 1 year of age who underwent epicardial PM placement were retrospectively evaluated. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02306-1
更新日期：2020-04-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0765-7
更新日期：2005-07-01 00:00:00
abstract：:Over the past decade, revolutionary advances in ultrasound imaging technology have allowed the study of the evolution of congenital heart disease during fetal life. The frustration arising from watching the prenatal progression of severe semilunar valve obstructions and therapy-refractory fetal arrhythmias has prompte...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-001-0197-6
更新日期：2002-05-01 00:00:00
abstract：:At the University of California Davis Medical Center, a screening fetal ultrasound examination (level I or II) incorporates a comprehensive segmental evaluation of the fetal heart. This study evaluated the reliability of the fetal ultrasound exam in the detection of abnormal heart anatomy. Our retrospective study revi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-0073-4
更新日期：2002-11-01 00:00:00
abstract：:A fetal echocardiographic scan was performed when routine prenatal ultrasound screening failed to identify four cardiac chambers. The scan showed a single ventricle with an associated circoid varicosity. Because of these anomalies, amniocentesis was suggested and trisomy 18 confirmed. The presence of major cardiac str...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794843
更新日期：1993-01-01 00:00:00
abstract：:M-mode and 2-dimensional (2D) echocardiographic imaging are routinely used to quantify left-ventricular (LV) size and function in pediatric patients with dilated cardiomyopathy (DCM). The reproducibility of and correlation between these techniques are unknown. This analysis sought to compare interreader, intrareader, ...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s00246-013-0835-9
更新日期：2014-04-01 00:00:00
abstract：:Different devices have been used for percutaneous closure of ventricular septal defects (VSDs). Over the past 6 months, we have used the Amplatzer duct occluder for VSDs associated with tunnel-shaped aneurysm in three patients here at our institution. Due to the anatomic resemblance between such VSDs and the duct occl...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9092-0
更新日期：2008-03-01 00:00:00
abstract：:We herein describe, for the first time, the fetal presentation of a case of ventricular inversion, restrictive ventricular septal defect, pulmonary stenosis, hypertensive left ventricle and double outlet right ventricle at 34 weeks of gestational age. Postnatal echocardiography confirmed the prenatal diagnosis. The pa...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-018-2048-8
更新日期：2019-01-01 00:00:00
abstract：:There is often a diagnostic dilemma in pediatric patients presenting with depressed ventricular function, as myocarditis and dilated cardiomyopathy (DCM) of other etiologies can appear very similar. Accurate identification is critical to guide treatment and to provide families with the most accurate expectation of lon...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1867-y
更新日期：2018-08-01 00:00:00
abstract：:Antenatal diagnosis of right heart enlargement has a wide spectrum of differential diagnosis from maternal, placental and fetal causes, and outcomes of all are not known. Coarctation of the aorta is in the differential diagnosis of right heart enlargement. In our study, we focused to measure multiple cardiac dimension...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1168-7
更新日期：2015-10-01 00:00:00
abstract：:This review outlines the morphologic and pathogenetic characteristics of congenital polyvalvular disease. Two cases are used for exemplification. The macroscopic and histologic features of the valves as well as associated cardiac lesions and clinical syndromes are described, followed by a discussion of morphogenesis o...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s002460010169
更新日期：2001-03-01 00:00:00
abstract：:Our objective was to understand the scope of pediatric heart failure (HF) and the current staffing environment of HF programs. An online survey was distributed to members of the Pediatric Heart Transplant Study and the Pediatric Council of the International Society for Heart and Lung Transplantation. All participants ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-017-1756-9
更新日期：2018-02-01 00:00:00
abstract：:Recurrent congestive heart failure (CHF) attributable to myocarditis is a seldom-discussed entity in the scientific literature. This report describes the case of an 8-year-old girl who had three clinically identical episodes of CHF, beginning at the age of 5 years, with each episode preceded by a viral prodrome. The c...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0109-3
更新日期：2012-01-01 00:00:00
abstract：:Ventriculo-coronary arterial connections are frequently observed in pulmonary atresia with intact interventricular septum. Sustained right ventricular hypertension during cardiac morphogenesis is thought to be responsible for persistence of myocardial sinusoidal-coronary artery connections. Considering an unusual obse...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900305
更新日期：1998-05-01 00:00:00
abstract：:Quantification of left ventricular (LV) mass by echocardiography has not been validated against the gold standard of cardiac magnetic resonance imaging (CMR) in the pediatric population. The purpose of this study was to compare LV mass by two-dimensional and conventional M-mode echocardiography versus CMR in children....
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1991-8
更新日期：2019-02-01 00:00:00
abstract：:A 39-week-old phenotypically female infant was born with hypoplastic left heart syndrome and expired on the third day of life. An autopsy revealed the patient to also have male pseudohermaphroditism and uterus bicornis bicollis. The association of hypoplastic left heart syndrome and male pseudohermaphroditism has been...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00795715
更新日期：1995-09-01 00:00:00
abstract：:Sinus node disease is a problem encountered in patients after the Mustard surgery, requiring a pacemaker implantation. The knowledge of the complexity anatomy is crucial because of the possible challenges associated with this procedure. We report a case of a 24-year-old woman presented with symptomatic bradycardia, in...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1155-z
更新日期：2015-08-01 00:00:00
abstract：:Serum troponin (Tn) is often elevated in viral myocarditis; however, its prognostic significance is unknown. We tested the hypothesis that abnormal serum Tn is associated with mortality in children hospitalized with myocarditis. We retrospectively studied data from six large children's hospitals participating in the P...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1871-2
更新日期：2018-08-01 00:00:00
abstract：:Non-invasive evaluation of right ventricular (RV) systolic function in neonates with pulmonary hypertension (PH) with traditional metrics including RV fractional area change (FAC) and tricuspid annular systolic plane excursion (TAPSE) has improved outcomes. Apical three-chamber (3C) RV-FAC, a novel tripartite assessme...
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更新日期：2020-08-01 00:00:00
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journal_title：Pediatric cardiology
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更新日期：2002-03-01 00:00:00
abstract：:We report our experience with asymptomatic valvar aortic stenosis diagnosed during infancy. During the period between November 1, 1986 and October 31, 1992 a total of 13 infants were diagnosed with asymptomatic aortic stenosis, 5 of whom showed rapid progression over the first 2 years of life. Two of these asymptomati...
journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：1997-01-01 00:00:00
abstract：:Two cases of arrhythmogenic right ventricular dysplasia (ARVD) in siblings are reported. In the boy, 14 years old, the clinical history, ECG, echocardiography, and histopathological findings were consistent with ARVD. Premature ventricular contractions of left bundle branch block (LBBB) pattern were recorded but no ve...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02239576
更新日期：1990-04-01 00:00:00
abstract：:Intramural coronary artery is known to be a risk factor for early death after an arterial switch operation (ASO). We evaluated the early and mid-term results of ASO for patients with intramural coronary artery. From September 2008 to March 2012, seven patients with an intramural coronary artery underwent ASO at our ho...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0968-5
更新日期：2015-01-01 00:00:00
