Long-term results of percutaneous radiofrequency ablation of unresectable colorectal hepatic metastases: final outcomes.

Abstract:

INTRODUCTION:Percutaneous radiofrequency ablation (PcRFA) provides alternative means of treating patients with unresectable colorectal liver metastases. We previously reported our initial experience in 30 patients treated with PcRFA. We present the final long-term results in these 30 patients. METHODS:The final outcome of the 30 patients treated with PcRFA is reported, 30 months following the initial results published in 2004. RESULTS:Thirty patients (21 males and 9 females), median age 74.5 (44-85) years, underwent PcRFA for 57 lesions in 60 sessions. The final results in this cohort of patients are reported: 28 dead and 2 lost to follow-up. Median follow-up was 22 (3-53) months. Median size was 31 (8-70) mm. Nineteen lesions required repeat PcRFA. Median ablation time per lesion was 12 (4.5-36) min. Eleven patients received chemotherapy pre-PcRFA and 15 received chemotherapy post-PcRFA. Three patients went on to have limited hepatectomies. Complications occurred in 3 (5%) and median hospital stay was 1 (1-7) day. The median hepatic disease-free survival was 12 (95% CI 6.1-17.9) months and actuarial survival was 23.2 (95% CI 18.5-27.8) months. CONCLUSION:PcRFA is safe and associated with increased disease-free and overall survival in patients with unresectable colorectal hepatic metastases.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

Suppiah A,White TJ,Roy-Choudhury SH,Breen DJ,Cast J,Maraveyas A,Hartley JE,Monson JR

doi

10.1159/000107717

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

358-60

issue

5

eissn

0253-4886

issn

1421-9883

pii

000107717

journal_volume

24

pub_type

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