Abstract:
INTRODUCTION:Percutaneous radiofrequency ablation (PcRFA) provides alternative means of treating patients with unresectable colorectal liver metastases. We previously reported our initial experience in 30 patients treated with PcRFA. We present the final long-term results in these 30 patients. METHODS:The final outcome of the 30 patients treated with PcRFA is reported, 30 months following the initial results published in 2004. RESULTS:Thirty patients (21 males and 9 females), median age 74.5 (44-85) years, underwent PcRFA for 57 lesions in 60 sessions. The final results in this cohort of patients are reported: 28 dead and 2 lost to follow-up. Median follow-up was 22 (3-53) months. Median size was 31 (8-70) mm. Nineteen lesions required repeat PcRFA. Median ablation time per lesion was 12 (4.5-36) min. Eleven patients received chemotherapy pre-PcRFA and 15 received chemotherapy post-PcRFA. Three patients went on to have limited hepatectomies. Complications occurred in 3 (5%) and median hospital stay was 1 (1-7) day. The median hepatic disease-free survival was 12 (95% CI 6.1-17.9) months and actuarial survival was 23.2 (95% CI 18.5-27.8) months. CONCLUSION:PcRFA is safe and associated with increased disease-free and overall survival in patients with unresectable colorectal hepatic metastases.
journal_name
Dig Surgjournal_title
Digestive surgeryauthors
Suppiah A,White TJ,Roy-Choudhury SH,Breen DJ,Cast J,Maraveyas A,Hartley JE,Monson JRdoi
10.1159/000107717subject
Has Abstractpub_date
2007-01-01 00:00:00pages
358-60issue
5eissn
0253-4886issn
1421-9883pii
000107717journal_volume
24pub_type
杂志文章abstract::A 26-year-old male was admitted to our hospital with a complaint of mild dysphagia. Preoperative examinations revealed a cystic lesion at the lower esophagus, thought to be a bronchogenic cyst. The patient underwent successful thoracoscopic tumor extirpation, assisted by endoscopy, without undergoing major thoracotomy...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000094751
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:The aim of this review is to summarize the available evidence for changes in bile composition following liver surgery and assess their use in predicting post-operative complications. MATERIALS AND METHODS:A literature search was undertaken for all studies focusing on bile composition, bile volume and anal...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000320459
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:It is unclear whether total gastrectomy (TG) is always necessary for gastric cancer of the cardia. We therefore investigated whether cardiac cancers treated by TG would have been cured by proximal gastrectomy (PG). METHODS:Photocopies of the resected stomachs of 55 patients who had received TG for cardiac c...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000052000
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Hilar resection in combination with extended liver resections has resulted in a higher rate of R0 resections and increased survival in patients with hilar cholangiocarcinoma (HCCA). This aggressive surgical approach is, however, associated with high rates of operative morbidity and mortality, largely due to ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000323825
更新日期:2011-01-01 00:00:00
abstract:AIMS:The present study was designed to evaluate the effects of perioperative treatment with TNP-470 on the resistance of colonic anastomoses. TNP-470 is a drug that was developed as an inhibitor of angiogenesis. METHODS:A colonic anastomosis was constructed in Sprague-Dawley rats. From 4 days before surgery to 4 days ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018820
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The repair of bile duct strictures (BDS) requires identification of healthy bile duct proximal to the stenosis. Identification may be difficult in complex bile duct injuries after cholecystectomy or partial liver resection. AIM:We describe a technique to identify the prestenotic bile duct using the sentinel...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000227276
更新日期:2009-01-01 00:00:00
abstract::The conventional methods of making an ileal J pouch require an enterotomy to introduce a linear stapler. We devised a new surgical technique that removes any need for this enterotomy by using both circular and linear staplers. We applied this method to two patients who underwent a total colectomy for ulcerative coliti...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000092843
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate the short-term surgical outcomes of laparoscopic intersphincteric resection (ISR) for lower rectal cancer, and to compare them with a case-control series of open ISR. METHODS:Between July 2002 and March 2011, 29 patients with lower rectal cancer underwent laparoscopic ISR, and 22 of 29 pati...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000332007
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Morbidity following pancreaticoduodenectomy (PD) has been reported to remain high. This study sought to measure the peak Hounsfield units (HUs) of visceral attenuation in patients undergoing PD and to assess the quality of adipocytes by comparing these measurements with perioperative factors. METHODS:Patien...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000505060
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Cholecystolithiasis is a common disease. Cholecystectomy is the main treatment method but is associated with various complications in some patients. This study explores a novel, minimally invasive surgery for the removal of calculi and the preservation of the gallbladder using a laparoscope combined with the...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000357823
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Living-donor liver transplantation using a right-lobe graft has increased the frequency of hilar anatomical variations despite its advantage of a larger graft volume. METHODS:Sixty-seven living-donor liver transplantations using right-lobe grafts are reviewed, regarding the surgical anatomy of hilar vascula...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000121907
更新日期:2008-01-01 00:00:00
abstract::The surgical management of gastroesophageal reflux disease has been simplified by the availability of minimally invasive techniques to treat this condition. The indications and selection of patients remain the same as for open surgery and initial results with laparoscopic antireflux surgery show long-term results equa...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000018686
更新日期:1999-01-01 00:00:00
abstract::Tumour recurrence that obstructs the afferent limb, blocking outflow of bile and pancreatic juice, constitutes a major clinical problem after a Whipple procedure. The endoscopic route is often not a possible alternative. Surgery may be difficult and perhaps dangerous to the often very sick patient and decompression wi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000071760
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/AIMS:Widespread clinical application of islet transplantation remains restricted, because of insufficient methods to prevent rejection and autoimmune destruction of islet grafts. In this study we demonstrate long-term function of islets of Langerhans within a capsule of porcine chondrocytes which may serve a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050130
更新日期:2001-01-01 00:00:00
abstract::One of the main reasons for the dismal prognosis of pancreatic ductal adenocarcinoma (PDAC) is its late diagnosis. At the time of presentation, only approximately 15-20% of all patients with PDAC are considered resectable and around 30% are considered borderline resectable. A surgical approach, which is the only curat...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000493466
更新日期:2019-01-01 00:00:00
abstract:AIMS:To compare the diagnostic value of endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) in the differentiation of malignant from benign masses in the pancreatic head. METHODS:Within 14 months 95 prospective patients with masses in the pancreatic head were assigned for preoperative...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000051942
更新日期:2000-01-01 00:00:00
abstract::The monocyte/macrophage plays a key role in the network of immune reactions. Dependent on activation, it is able to produce various cytokines which act on other cells of the immune system in the sense of upregulation or downregulation. In addition, it presents antigens by the HLA-DR molecule as an initial trigger of a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018601
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:Graft failure is a critical complication associated with vascular occlusion in esophageal reconstruction with a free jejunal graft following pharyngolaryngoesophagectomy. In this study, we evaluated the usefulness of intramucosal pH (pHi) measurement using a tonometer to assess the graft viability. MET...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000102902
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To review the current management of achalasia, and the controversies regarding the different treatment options. METHODS:A review of the literature was performed. The key words used were esophageal achalasia, Heller myotomy, endoscopic balloon dilatation, laparoscopic Heller myotomy, and fundoplication. RESU...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000079341
更新日期:2004-01-01 00:00:00
abstract::In this review, the function of the sphincter of Oddi (SO) is detailed in terms of normal motility, neural and hormonal control of SO function, coordination between gallbladder and SO motility, and correlation of motility of the SO and the duodenum. In addition, SO function tests, such as the morphine Prostigmin test ...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000286464
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:In the management of pancreatic cystic neoplasms (PCN), size plays a crucial role as the expression of disease progression. While many evidences regarding the natural history of growing pancreatic cysts exist, almost no data are available regarding cysts with a reduction in size. METHODS:Radiological and ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000485199
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Perianal warts are common, and may be extensive. Electrocoagulation is a recognised management option. METHOD:A 20-year-old male underwent electrocautery of extensive perianal warts. He presented 3 months postoperatively with constipation and inability to defecate. Examination revealed severe perianal stric...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018856
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The prognosis of patients with pancreatic cancer is poor. This is mainly caused by the late diagnosis, the aggressive biology and the lack of effective treatment modalities. Adenoviral gene therapy has the potential to selectively treat both primary tumor and (micro)metastatic tissue. METHODS:This review pr...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000145981
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Although evidence is growing that most patients who need an operation for diverticular disease of the sigmoid colon can be treated by a single-stage procedure, a two-stage procedure will still be necessary in some patients because of significant sepsis or technical difficulties. The outcomes of 65 patients w...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000091444
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:The extent of optimal gastric resection for proximal gastric cancer (PGC) continues to remain controversial, and a final consensus is yet to be met. The current study aimed to compare the perioperative outcomes, postoperative complications, and overall survival (OS) of proximal gastrectomy (PG) versus tota...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000506104
更新日期:2021-01-01 00:00:00
abstract::A 64-year-old man with Muir-Torre syndrome (MTS), a condition characterized by the association of multiple sebaceous tumours and kerato-acanthomas with internal malignancies, developed a carcinoma of the ampulla of Vater. This is the 2nd reported ampullary carcinoma in 205 reported cases of MTS, suggesting a higher pr...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000052010
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND/AIM:Laparoscopy-assisted surgery has proved useful in the treatment of early gastric cancer, but its use in advanced cancer has rarely been studied. To investigate the efficacy and advantages of laparoscopy-assisted distal gastrectomy (LADG) with D2 dissection of lymph nodes versus conventional open D2 dista...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000281818
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Different results and opinions exist concerning the use of a standard or an extended lymphadenectomy, and about the indications for portal vein resection in the surgical treatment of pancreatic cancer. The site of recurrence of pancreatic cancer may help to define the usefulness of different treatments in av...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000018735
更新日期:1999-01-01 00:00:00
abstract::The intestinal barrier function is considered to play an important role in protecting the penetration of luminal antigens, associated with the development of secondary infection and sepsis and the initiation of the multiple organ dysfunction syndrome. The intestinal mucosal barrier against luminal macromolecules and m...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018651
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Vagus nerve injury (VNI) is a feared complication of antireflux surgery (ARS). The impact of VNI on the functional outcomes of ARS has not yet been evaluated systematically. The aim of this review was to evaluate the impact of VNI on functional and clinical outcome of ARS. METHODS:A systematic search was pe...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000444147
更新日期:2016-01-01 00:00:00