Topical phenytoin in diabetic foot ulcers.

abstract：OBJECTIVE:To assess effectiveness of inpatient hybrid closed-loop control (HCLC) followed by outpatient sensor-augmented pump (SAP) therapy initiated within 7 days of diagnosis of type 1 diabetes on the preservation of β-cell function at 1 year. RESEARCH DESIGN AND METHODS:Sixty-eight individuals (mean age 13.3 ± 5.7 ...

journal_title：Diabetes care

authors： Buckingham B,Beck RW,Ruedy KJ,Cheng P,Kollman C,Weinzimer SA,DiMeglio LA,Bremer AA,Slover R,Tamborlane WV,Diabetes Research in Children Network (DirecNet) Study Group.,Type 1 Diabetes TrialNet Study Group.

更新日期：2013-12-01 00:00:00

abstract：:Use of continuous subcutaneous insulin infusion requires continuing available care by skilled professionals, careful selection of patients, meticulous patient monitoring, and provisions for recording and reporting experiences. Insulin pumps prescribed by a physician within these guidelines are a part of treatment and ...

journal_title：Diabetes care

authors：

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:This study tested the hypothesis that genetically raised hyperglycemia increases coronary artery disease (CAD) risk separately from the risk conferred by type 2 diabetes as a whole. RESEARCH DESIGN AND METHODS:We conducted a Mendelian randomization (MR) analysis using summary-level statistics from the larges...

journal_title：Diabetes care

authors： Merino J,Leong A,Posner DC,Porneala B,Masana L,Dupuis J,Florez JC

更新日期：2017-05-01 00:00:00

abstract：:An increasing amount of health care today is directed to the amelioration of chronic diseases for which there are no cures. Technological advances and the aging of the population have increased the costs of that care. In an attempt to control costs and increase the efficiency of health care, it is being increasingly d...

journal_title：Diabetes care

authors： Geffner DL

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

journal_title：Diabetes care

authors： Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To create a simple prediction rule that could perform as well as the 2-h postchallenge plasma glucose (PCPG) test to predict those at risk for diabetes. We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort. RESEARCH DESIGN AND METHODS:A cross-se...

journal_title：Diabetes care

authors： Kanaya AM,Wassel Fyr CL,de Rekeneire N,Shorr RI,Schwartz AV,Goodpaster BH,Newman AB,Harris T,Barrett-Connor E

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:We have investigated age-period-cohort effects and spatial and temporal trends for the incidence of type 1 diabetes among 0- to 14-year-old children in Norway. RESEARCH DESIGN AND METHODS:We included children with the diagnosis of type 1 diabetes in Norway during 1973-1982 and 1989-2003. We studied age, cale...

journal_title：Diabetes care

authors： Aamodt G,Stene LC,Njølstad PR,Søvik O,Joner G,Norwegian Childhood Diabetes Study Group.

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:Raloxifene hydrochloride is a selective estrogen receptor modulator that to date has not been shown to cause hypertriglyceridemia in normal, diabetic, or hypertriglyceridemic women. This study was designed to assess the effect of raloxifene on serum triglycerides in postmenopausal women who have a history of ...

journal_title：Diabetes care

authors： Carr MC,Knopp RH,Brunzell JD,Wheeler BS,Zhu X,Lakshmanan M,Rosen AS,Anderson PW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To address whether hemodynamic responses in the cerebral arteries and OAs may be altered in patients with diabetic retinopathy. We used TCD to evaluate the effects of changes in BP, posture, and exercise on MCA and OA blood flow velocities. RESEARCH DESIGN AND METHODS:We evaluated 13 patients with BDR, 19 wi...

journal_title：Diabetes care

authors： Albert SG,Gomez CR,Russell S,Chaitman BR,Bernbaum M,Kong BA

更新日期：1993-02-01 00:00:00

abstract：:Cardiovascular outcome trials have provided evidence that sodium-glucose cotransporter 2 inhibitor (SGLT2i) treatment is associated with remarkably favorable cardiovascular outcomes. Here, we offer a novel hypothesis that may encompass many of these hypothetical mechanisms, i.e., the ability of SGLT2i to modify the tr...

journal_title：Diabetes care

authors： Avogaro A,Fadini GP,Del Prato S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To investigate the association of carotid atherosclerosis and serum lipoprotein(a) [Lp(a)] concentrations in subjects with NIDDM. RESEARCH DESIGN AND METHODS:We measured carotid intima-media thickness (IMT) and Lp(a) concentrations in 117 NIDDM subjects. Subjects were divided into tertiles according to IMT v...

journal_title：Diabetes care

authors： Yamamoto M,Egusa G,Yamakido M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To study the effect of birth weight on risk of type 2 diabetes in the schoolchildren in Taiwan. RESEARCH DESIGN AND METHODS:From 1992 to 1997, all schoolchildren aged 6-18 years were screened for diabetes in Taiwan Province. This cohort consisted of 1,966 patients with diabetes and 1,780 randomly selected su...

journal_title：Diabetes care

authors： Wei JN,Sung FC,Li CY,Chang CH,Lin RS,Lin CC,Chiang CC,Chuang LM

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine medication adherence and other self-management practices as potential determinants of higher glycemic risk among black relative to white patients. RESEARCH DESIGN AND METHODS:We used a retrospective, longitudinal repeated-measures design to model the contribution of m...

journal_title：Diabetes care

authors： Adams AS,Trinacty CM,Zhang F,Kleinman K,Grant RW,Meigs JB,Soumerai SB,Ross-Degnan D

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To examine the magnitude and types of hospitalizations among persons with prediabetes, undiagnosed diabetes, and diagnosed diabetes. RESEARCH DESIGN AND METHODS:This study included 13,522 participants in the Atherosclerosis Risk in Communities (ARIC) study (mean age 57 years, 56% female, 24% black, 18% with ...

journal_title：Diabetes care

authors： Schneider AL,Kalyani RR,Golden S,Stearns SC,Wruck L,Yeh HC,Coresh J,Selvin E

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS:In 1,165 American type 1 diabetic patients with and without DN selected...

journal_title：Diabetes care

authors： Gu HF,Zheng X,Abu Seman N,Gu T,Botusan IR,Sunkari VG,Lokman EF,Brismar K,Catrina SB

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To project the number of people with diagnosed diabetes in the U.S. through 2050, accounting for changing demography and diabetes prevalence rates. RESEARCH DESIGN AND METHODS:We combined age-, sex-, and race-specific diagnosed diabetes prevalence rates-predicted from 1980-1998 trends in prevalence data from...

journal_title：Diabetes care

authors： Boyle JP,Honeycutt AA,Narayan KM,Hoerger TJ,Geiss LS,Chen H,Thompson TJ

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Antioxidant trials have not demonstrated efficacy in slowing cardiovascular disease but could not rule out benefit for specific patient subgroups. Antioxidant therapy reduces LDL oxidizability in haptoglobin 1 allele homozygotes (Hp 1-1), but not in individuals with the haptoglobin 2 allele (Hp 2-1 or Hp 2-2)...

journal_title：Diabetes care

authors： Levy AP,Friedenberg P,Lotan R,Ouyang P,Tripputi M,Higginson L,Cobb FR,Tardif JC,Bittner V,Howard BV

更新日期：2004-04-01 00:00:00

abstract：:The economic burden of diabetes in the U.S. is now more than 90 billion dollars per year (113-115). In the diabetes community, there is a feeling that aggressive measures to detect diabetes in earlier stages may be warranted. Regardless of whether evidence is convincing that there are benefits from early detection of ...

journal_title：Diabetes care

authors： Engelgau MM,Aubert RE,Thompson TJ,Herman WH

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of normal aging on the protective responses against hypoglycemia, in view of the fact that type II diabetes is primarily a disease of aging, and its treatment is associated with risk of hypoglycemia with cognitive impairment. RESEARCH DESIGN AND METHODS:Plasma glucose was lowered st...

journal_title：Diabetes care

authors： Matyka K,Evans M,Lomas J,Cranston I,Macdonald I,Amiel SA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:To study how type 2 diabetes adversely affects brain volumes, changes in volume, and cognitive function. RESEARCH DESIGN AND METHODS:Regional brain volumes and ischemic lesion volumes in 1,366 women, aged 72-89 years, were measured with structural brain magnetic resonance imaging (MRI). Repeat scans were col...

journal_title：Diabetes care

authors： Espeland MA,Bryan RN,Goveas JS,Robinson JG,Siddiqui MS,Liu S,Hogan PE,Casanova R,Coker LH,Yaffe K,Masaki K,Rossom R,Resnick SM,WHIMS-MRI Study Group.

更新日期：2013-01-01 00:00:00

abstract：:The issue of statin-associated cognitive impairment has been a hot topic among both patients and health care providers, especially since the U.S. Food and Drug Administration (FDA) issued a statement regarding rare postmarketing reports of ill-defined cognitive impairment associated with statin use. This statement was...

journal_title：Diabetes care

authors： Bitzur R

更新日期：2016-08-01 00:00:00

abstract：:OBJECTIVE We tested whether average monthly glycemic burden (AMGB), a marker of hyperglycemia that is a function of the extent and duration that A1C exceeded 7%, indicated greater risk of cardiovascular disease (CVD) than traditional A1C measures. RESEARCH DESIGN AND METHODS Using a case-control design, we studied 2,4...

journal_title：Diabetes care

authors： Nichols GA,Rosales AG,Perrin NA,Fortmann SP

更新日期：2014-01-01 00:00:00

abstract：:In search of possible interactions between plastic tubings used for insulin-pump treatment and commercial regular insulin preparations, various catheter sets made from polyvinyl chloride (PVC), polyethylene (PE), and nylon plastics were perfused at 30 degrees C in a laboratory setting for up to 72 h. The perfused insu...

journal_title：Diabetes care

authors： Chantelau E,Lange G,Gasthaus M,Boxberger M,Berger M

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:People with type 2 diabetes are at increased risk of age-related cognitive decline and dementia. Hypoglycemia is a candidate risk factor, but the direction of association between episodes of severe hypoglycemia and cognitive decline in type 2 diabetes remains uncertain. RESEARCH DESIGN AND METHODS:In the Edi...

journal_title：Diabetes care

authors： Feinkohl I,Aung PP,Keller M,Robertson CM,Morling JR,McLachlan S,Deary IJ,Frier BM,Strachan MW,Price JF,Edinburgh Type 2 Diabetes Study (ET2DS) Investigators.

更新日期：2014-02-01 00:00:00

abstract：:The availability of insulin analogs has offered insulin replacement strategies that are proposed to more closely mimic normal human physiology. Specifically, there are a considerable number of reports demonstrating that prandial insulin analogs (lispro, aspart, glulisine) have pharmacokinetic and pharmacodynamic profi...

journal_title：Diabetes care

authors： Davidson MB

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To provide a description of the clinical characteristics that distinguish individuals who withhold insulin for weight control from those who do not. Some individuals with insulin-dependent diabetes mellitus (IDDM) control their weight by withholding insulin and purging excessive calories. This process places ...

journal_title：Diabetes care

authors： Biggs MM,Basco MR,Patterson G,Raskin P

更新日期：1994-10-01 00:00:00

abstract：:In past studies on the psychological aspects of diabetes mellitus, symptoms of depression have been identified as the most common manifestation among diabetic patients. Other psychological manifestations have been anxiety, hypochondriasis, increased dependence and passivity, and poor self-image. Ten insulin-dependent ...

journal_title：Diabetes care

authors： Dupuis A

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to identify predictors of the onset of disturbed eating behavior (DEB) in adolescent girls with type 1 diabetes. RESEARCH DESIGN AND METHODS:In this prospective study, participants completed the Children's Eating Disorder Examination interview and self-report measures at baselin...

journal_title：Diabetes care

authors： Olmsted MP,Colton PA,Daneman D,Rydall AC,Rodin GM

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:There is considerable interest in identifying biomarkers that predict high risk for the development of macrovascular complications in patients with diabetes. Therefore, the longitudinal association between subclinical atherosclerosis as measured by internal carotid artery intima-media thickness (IMT) and acut...

journal_title：Diabetes care

authors： Hunt KJ,Baker NL,Cleary PA,Klein R,Virella G,Lopes-Virella MF,DCCT\/EDIC Group of Investigators.

更新日期：2015-07-01 00:00:00