Abstract：
:To implement preventive policies of disability in older diabetic people, the role of diabetes in the disablement process should be investigated. Diabetes mellitus is consistently associated with a higher prevalence of disability at all states, as well as with a progression in disability states and may be considered as a brake on recovery. This association is partially explained by existing complications, associated conditions (obesity, depression, arterial hypertension) treatment burden, and other social characteristics (lower income, lower educational level). Finally, in the disablement process, the role of altered muscle metabolism due to diabetes, aging, nutrition and sedentary lifestyle may represent a major target for interventions to improve functions and potentially activities in elderly people.
journal_name
Diabetes Metabjournal_title
Diabetes & metabolismauthors
Bourdel-Marchasson I,Helmer C,Fagot-Campagna A,Dehail P,Joseph PAdoi
10.1016/s1262-3636(07)80058-9subject
Has Abstractpub_date
2007-04-01 00:00:00pages
S66-74eissn
1262-3636issn
1878-1780pii
S1262-3636(07)80058-9journal_volume
33 Suppl 1pub_type
杂志文章,评审abstract：AIM:Different treatment strategies have been used to manage adolescents with poorly controlled type 1 diabetes. We investigated whether a brief elective hospital admission improves haemoglobin A(1c) (HbA(1c)) over 12 months. METHODS:We studied a retrospective cohort of adolescents with poorly controlled type 1 diabete...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2013.04.003
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVES:The aim of the present study was to investigate insulin secretion, insulin-receptor binding and peripheral insulin sensitivity in subjects with different degrees of obesity. METHODS:36 obese subjects with normal glucose tolerance and different degrees of obesity and 40 healthy normal-weight subjects partici...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/s1262-3636(07)70138-6
更新日期：2004-11-01 00:00:00
abstract：AIM:Cholesterol intake is associated with the risk for type 2 diabetes mellitus, but no previous studies have evaluated its role regarding the risk of gestational diabetes mellitus (GDM). We investigate the relation between cholesterol intake and GDM. METHODS:At screening for GDM, 335 pregnant women were evaluated for...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2006.07.002
更新日期：2007-02-01 00:00:00
abstract：OBJECTIVES:To analyze pulse pressure (PP) as a risk predictor for coronary heart disease (CHD), stroke and cardiovascular disease (CVD; CHD and/or stroke) in type 2 diabetic patients. METHODS:A total of 11,128 female and male type 2 diabetic patients with known baseline PP values and no CVD, aged 50-74 years, were fol...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2009.04.010
更新日期：2009-12-01 00:00:00
abstract：AIMS:To evaluate whether perception of insulin therapy differs between patients with type 2 diabetes treated with insulin and those treated with oral hypoglycaemic agents (OHAs), and to examine whether gender, education level, injection duration and mode of injection were associated with the patients' perception of ins...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2010.12.008
更新日期：2011-11-01 00:00:00
abstract：AIM:Determine whether plasma omega-7 vaccenic acid and palmitoleic acid levels are related to homeostasis model of insulin resistance scores and incident type II diabetes, and whether race/ethnicity modifies these associations. METHODS:Plasma phospholipid fatty acids were measured by gas chromatography with flame-ioni...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2019.10.005
更新日期：2020-09-01 00:00:00
abstract：:With improvements in patient and graft survival, increasing attention has been placed on complications that contribute to long-term patient morbidity and mortality. New-onset diabetes after transplantation (NODAT) is a common complication of solid-organ transplantation, and is a strong predictor of graft failure and c...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：10.1016/j.diabet.2010.09.003
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:Recently, the association of the natural variants rs1260326 and rs780094 of the glucokinase regulatory protein (GCKR) gene with increased fasting triglycerides and decreased fasting plasma glucose in diabetic adults was reported; the minor alleles were also found to reduce the risk of type 2 diabetes. The pre...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2011.02.003
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:End-stage renal disease (ESRD) requiring renal replacement therapy (RRT) is a late complication of type 2 diabetes. The correlation between pre-ESRD medical care and outcome has been rarely studied in France. METHODS:Community-based study of case-incIdent ESRD patients. Medical care practices were described ...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/s1262-3636(07)70091-5
更新日期：2004-02-01 00:00:00
abstract：:We report the case of a young insulin-dependent diabetic patient in whom acute renal failure led to detection of ureterohydronephrosis secondary to neurogenic bladder. The persistence of a high daily urine volume revealed diabetes insipidus, suggesting Wolfram syndrome, which was confirmed by the diagnosis of optic at...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：AIM:Adiponectin levels in skeletal muscle and adipose tissue have been reported to be involved in insulin resistance in rats fed with a high-fat diet (HFD). Our objective was to explore whether adiponectin is also expressed in the pancreas and what its potential role is during the development of type 2 diabetes (T2D) i...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2014.05.004
更新日期：2014-11-01 00:00:00
abstract：:Continuous subcutaneous insulin infusion (CSII) using an external pump is widely used for the treatment of type 1 diabetes, but has been less evaluated in type 2 diabetes. This review analyzes the open-label as well as randomized controlled studies performed in type 2 diabetic patients. The efficacy of CSII is compare...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：10.1016/j.diabet.2010.08.002
更新日期：2010-12-01 00:00:00
abstract：:Non-obese diabetic (NOD) mice spontaneously develop T-cell-mediated autoimmune diabetes. Initial work on the diabetogenic T-cell repertoire indicated that autoreactive T lymphocytes were polyclonal but that the presence of specific subsets (V beta 8 or V beta 6) might be required for induction of the disease. Further ...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：:We present the first case of muscle infarction in a 30-year-old woman who had a 5-year history of type 1 diabetes mellitus that was not complicated by nephropathy, retinopathy or neuropathy. All common causes of muscle infarction were excluded, particularly microangiopathy and a hypercoagulable state. The differential...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2007.06.003
更新日期：2007-12-01 00:00:00
abstract：AIM:To examine the association between treatment-achieved HbA1c values and incidence of both coronary artery disease (CAD) and severe eye disease with different diabetes treatments. METHODS:Associations of treatment-achieved HbA1c were investigated in various treatment groups [diet only; insulin; sulphonylurea (SU) al...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2018.08.009
更新日期：2020-09-01 00:00:00
abstract：:Insulin resistance was already suspected in the thirties from clinical observations in diabetic patients, then better appreciated in the early sixties with the development of insulin radioimmunoassay, and finally confirmed in the last 20 years by using various sophisticated methods able to quantify insulin action. Fir...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：
更新日期：2001-04-01 00:00:00
abstract：:The timely series of state-of-the-art reviews contained within this supplement provide a valuable overview of the current state of diabetes care, and the pharmacological interventions we have available. Our experts agree that one of the most important lessons to emerge recently concerns the magnitude of the malign inf...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/s1262-3636(03)72797-9
更新日期：2003-09-01 00:00:00
abstract：:ATP-sensitive potassium channels (K(ATP)) couple cell metabolism to electrical activity by regulating potassium movement across the membrane. These channels are octameric complex with two kind of subunits: four regulatory sulfonylurea receptor (SUR) embracing four poreforming inwardly rectifying potassium channel (Kir...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：10.1016/S1262-3636(07)70311-7
更新日期：2006-12-01 00:00:00
abstract：AIM:This study investigated the relationship between endothelial dysfunction (ED) and arterial stiffness (AS) in adults with type 1 diabetes and no clinical cardiovascular (CV) disease. METHODS:A total of 68 patients with type 1 diabetes and 68 age- and gender-matched healthy (non-diabetic) subjects were evaluated. ED...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2013.03.006
更新日期：2013-09-01 00:00:00
abstract：AIM:To investigate the effect of changes in fasting plasma glucose (FPG) variability, as assessed by 2-year trajectories of FPG variability, on mortality risk in patients with type 2 diabetes (T2D). METHODS:From 2009 to 2012, outpatients with T2D, aged>18 years, were enrolled from a medical centre. FPG was measured ev...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/j.diabet.2017.09.001
更新日期：2018-03-01 00:00:00
abstract：:Pancreatic transplantation is the best method of replacing the endocrine function of the gland in Type 1 insulin-dependent diabetic patients. At the end of 1996, 9,000 pancreas transplants had been reported to the international Pancreas Transplant Registry. For 1994-1996, one-year pancreas survival rates were 81% for ...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:To test the hypothesis that smokers have a higher frequency of the metabolic syndrome, and a syndrome with different characteristics than non-smokers. MATERIAL AND METHODS:The 2,569 men and 2,637 women included in the D.E.S.I.R. study, aged 30-64 years, volunteers from ten French Social Security Health Exam...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,多中心研究
doi：10.1016/s1262-3636(07)70031-9
更新日期：2003-06-01 00:00:00
abstract：:Insulin-requiring diabetes (IRD) is a condition of permanent blood glucose imbalance which occurs despite a regulated diet and treatment with maximum doses of oral anti-diabetic drugs (glibenclamide 15 mg/d + metformin 1,700 mg/d). This report describes the results of a 2-year prospective study in 75 IRD patients trea...
journal_title：Diabetes & metabolism
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：AIM:To explore if efficacy and safety findings for insulin glargine 300U/mL (Gla-300) versus insulin glargine 100U/mL (Gla-100), observed over 6 months in insulin-naïve people with type 2 diabetes, are maintained after 12 months. METHODS:EDITION 3 was a phase 3a, randomized, multicentre, open-label, parallel-group, tr...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.diabet.2017.04.007
更新日期：2017-09-01 00:00:00
abstract：:The CGMS (Continuous Glucose Monitoring System) is a portable device allowing continuous measuring of glucose. It provides recordings of at least 72 h, during which 288 measures/day are performed. Results are visualised in the form of a set of curves, illustrating the variations in blood glucose levels over time. The ...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：10.1016/s1262-3636(07)70258-6
更新日期：2006-04-01 00:00:00
abstract：AIMS:To evaluate factors associated with reaching or not reaching target glycated haemoglobin (HbA1c) levels by analysing the respective contributions of fasting hyperglycaemia (FHG), also referred to as basal hyperglycaemia, vs postprandial hyperglycaemia (PHG) before and after initiation of a basal or premixed insuli...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.diabet.2016.10.005
更新日期：2017-02-01 00:00:00
abstract：AIM:To investigate the locus of control in patients with type 2 diabetes followed by systemic group education (Group Care) and traditional one-to-one care. METHODS:In a post-hoc analysis, two questionnaires were administered to 56 patients who had been followed for 5-7 years by Group Care and 51 controls followed by i...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/s1262-3636(07)70250-1
更新日期：2006-02-01 00:00:00
abstract：:Bariatric surgery can be proposed to address severe obesity associated with comorbid conditions, when medical treatment has failed. Three surgical techniques are currently available, including 2 using coelioscopy. Short term results are encouraging regarding weight loss, which is linked with a reduction in comorbid co...
journal_title：Diabetes & metabolism
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：:The capacity of cardiac myocyte to regulate ATP production to face any change in energy demand is a major determinant of cardiac function. Because FA is the main heart fuel (although the most expensive one in oxygen, and prompt to induce deleterious effects), this process is based on a balanced fatty acid (FA) metabol...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:To determine the utility of the continuous glucose monitoring system (CGMS) as an outpatient procedure to improve management of diabetes in adolescents. RESEARCH DESIGN AND METHODS:Twelve adolescents (mean age: 16.2 +/- 3 years) with poorly controlled type 1 diabetes (HbA(1c) > 8%) were included in this tria...
journal_title：Diabetes & metabolism
pub_type： 杂志文章
doi：10.1016/s1262-3636(07)70076-9
更新日期：2003-12-01 00:00:00
