Hippocampal calcium dyshomeostasis and long-term potentiation in 2-week zinc deficiency.

abstract：:Aminoethylcysteine ketimine is a sulfur-containing cyclic compound produced by the enzymatic alpha-deamination of the parent aminoethylcysteine that has been detected in bovine brain and cerebellum. Aminoethylcysteine ketimine is known to dimerize spontaneously and easily lose one carboxyl group. This decarboxylated c...

journal_title：Neurochemistry international

authors： Matarese RM,Macone A,Crescentini G,Duprè S,Cavallini D

更新日期：1998-04-01 00:00:00

abstract：:Depression is highly comorbid with anxiety disorders and associated with profound cognitive impairment. Moreover, cognitive deficits associated with hippocampal dysfunction are central in depression and anxiety disorders. Furthermore, depression is accompanied by glutamatergic dysfunction which can further impair the ...

journal_title：Neurochemistry international

authors： Chakraborty S,Tripathi SJ,Srikumar BN,Raju TR,Shankaranarayana Rao BS

更新日期：2020-01-01 00:00:00

abstract：:E1 mice are an animal model of human epilepsy (idiopathic complex partial seizures). We have previously demonstrated abrupt poly(A)(+) RNA expression in liver from 1-day-old E1 mouse [Mita et al., 1991. Devl. Brain Res. 64, 27-35]. In the present study, we constructed a cDNA library of the poly(A)(+) RNA. By analyzing...

journal_title：Neurochemistry international

authors： Mita T,Kawazu I,Hirano H,Ohmori O,Janjua N,Shibata K

更新日期：2001-04-01 00:00:00

abstract：:The discovery of nonsynaptic communication in the 1960s and 1970s was an important milestone in investigating the function of the nervous system, and it revolutionized our view about information transmission between neurons. In addition, nonsynaptic communication has a practical importance not only within the nervous ...

journal_title：Neurochemistry international

authors： Selmeczy Z,Vizi ES,Csóka B,Pacher P,Haskó G

更新日期：2008-01-01 00:00:00

abstract：:Increased noradrenaline, induced by rapid eye movement (REM) sleep deprivation, stimulates Na-K ATPase activity in the rat brain. The brain contains neurons as well as glia and both possess Na-K ATPase, however, it was not known if REM sleep deprivation affects the enzyme in both types of cells identically. Rats were ...

journal_title：Neurochemistry international

authors： Baskey G,Singh A,Sharma R,Mallick BN

更新日期：2009-01-01 00:00:00

abstract：:Using specific antibodies to met-enkephalin, met-enkephalin-Arg(6)-Phe(7) and met-enkephalin-Arg(6)-Gly(7)-Leu(8), we have studied the distribution of these opioid peptides in the frog adrenal gland by means of the indirect immunofluorescence technique. Bright staining of all chromaffin cells was observed by applicati...

journal_title：Neurochemistry international

authors： Leboulenger F,Cupo A,Castanas E,Benyamina M,Pelletier G,Vaudry H

更新日期：1986-01-01 00:00:00

abstract：:Oxidative stress (OS) has been related to cocaine's actions and also to numerous nervous system pathologies, including seizures. The purpose of this work was to determine the alterations in glutathione (GSH) content, nitrite/nitrate and MDA levels after cocaine-induced toxicity. Male Swiss mice were injected (i.p.) wi...

journal_title：Neurochemistry international

authors： Macêdo DS,Vasconcelos SM,Andrade-Neto M,Belchior LD,Honório Júnior JE,Gonçalves DO,Fonteles MM,Silva MI,Aguiar LM,Viana GS,de Sousa FC

更新日期：2010-01-01 00:00:00

abstract：:Rasagiline is a propargylamine and irreversible monoamine oxidase (MAO) B inhibitor used for the treatment of Parkinson's disease (PD). It has demonstrated neuroprotective properties in laboratory studies. Current concepts of PD aetiopathogenesis include the role of alpha-synuclein, protein aggregation, free radical m...

journal_title：Neurochemistry international

authors： Chau KY,Cooper JM,Schapira AH

更新日期：2010-11-01 00:00:00

abstract：:Neurons with colocalized cholecystokinin and dopamine are present predominantly in the ventral tegmental area and project mainly to the caudal part of the medial nucleus accumbens. The activity of this dopamine system can be evaluated by means of the intracranial self-stimulation behavior on male Wistar rats having ch...

journal_title：Neurochemistry international

authors： De Witte P,Heidbreder C,Roques B,Vanderhaeghen JJ

更新日期：1987-01-01 00:00:00

abstract：:Protein kinase C (PKC) is involved in several cell events including proliferation, survival and differentiation. The aim of this work was to investigate the role of PKC activation on retinal cells proliferation. We demonstrated that PKC activation by phorbol 12-myristate 13-acetate (PMA), a tumor promoter phorbol este...

journal_title：Neurochemistry international

authors： dos Santos AA,Medina SV,Sholl-Franco A,de Araujo EG

更新日期：2003-01-01 00:00:00

abstract：:The iron siderophore binding protein lipocalin 2 (LCN2, also known as 24p3, NGAL and siderocalin) may be involved in iron homeostasis, but to date, little is known about expression of its putative receptor, brain-type organic cation transporter (BOCT, also known as BOCT1, 24p3R, NGALR and LCN2R), in the brain during n...

journal_title：Neurochemistry international

authors： Chia WJ,Tan FC,Ong WY,Dawe GS

更新日期：2015-08-01 00:00:00

abstract：:A low density of brain IR2-imidazoline receptive sites has previously been linked to depression. In this study we evaluated brain IR2-binding sites in a rat model of depression, olfactory bulbectomy, and determined the effects of chronic imipramine treatment in vivo on these sites. Compared with sham-operated controls...

journal_title：Neurochemistry international

authors： Zhu H,Paul IA,McNamara M,Redmond A,Nowak G,Piletz JE

更新日期：1997-01-01 00:00:00

abstract：:The 12/15-lipoxygenase (12/15-LOX) enzymes react with polyunsaturated fatty acids producing active lipid metabolites that are involved in plethora of human diseases including neurological disorders. A great many of elegant studies over the last decades have contributed to unraveling the mechanism how 12/15-lipoxygenas...

journal_title：Neurochemistry international

authors： Li QQ,Li Q,Jia JN,Liu ZQ,Zhou HH,Mao XY

更新日期：2018-09-01 00:00:00

abstract：:Succinyl-Leu-Leu-Val-Tyr-4-methylcoumaryl-7-amide (Suc-LLVY-MCA) hydrolyzing activities of the 20S and 26S proteasomes in the gerbil cortex following transient forebrain ischemia were examined. Using extraction solutions without ATP, only 20S proteasome activity was noted after separation with glycerol gradient centri...

journal_title：Neurochemistry international

authors： Kamikubo T,Hayashi T

更新日期：1996-02-01 00:00:00

abstract：:Amyloid deposition within the brains of Alzheimer's Disease patients results in the activation of microglial cells and the induction of a local inflammatory response. The interaction of microglia or monocytes with beta-amyloid (A beta) fibrils elicits the activation a complex tyrosine kinase-based signal transduction ...

journal_title：Neurochemistry international

authors： Combs CK,Bates P,Karlo JC,Landreth GE

更新日期：2001-11-01 00:00:00

abstract：UNLABELLED:The aggregates of amyloid beta peptides (Aβs) are regarded as one of the main pathological hallmarks of Alzheimer's disease (AD). An imbalance between the rates of synthesis and clearance of Aβs is considered to be a possible cause for the onset of AD. Dipeptidyl peptidases II and IV (DPPII and DPPIV) are se...

journal_title：Neurochemistry international

authors： Sharoyan S,Antonyan A,Mardanyan S,Harutyunyan H,Movsisyan N,Hovnanyan N,Hovnanyan K

更新日期：2013-06-01 00:00:00

abstract：:Mitochondrial respiratory chain (RC) disease is a heterogeneous and highly morbid group of energy deficiency disorders for which no proven effective therapies exist. Robust vertebrate animal models of primary RC dysfunction are needed to explore the effects of variation in RC disease subtypes, tissue-specific manifest...

journal_title：Neurochemistry international

authors： Byrnes J,Ganetzky R,Lightfoot R,Tzeng M,Nakamaru-Ogiso E,Seiler C,Falk MJ

更新日期：2018-07-01 00:00:00

abstract：:The use of synthetic antisense oligonucleotides as specific inhibitors of gene expression exploits the susceptibility of mRNA to functional blockade at several levels, including mRNA processing, transport, translation and degradation. It is becoming increasingly apparent that the actions of these synthetic oligomers a...

journal_title：Neurochemistry international

authors： Knee R,Murphy PR

更新日期：1997-09-01 00:00:00

abstract：:NMDA receptors are essential for neurotransmission and key mediators of synaptic signaling, but they can also trigger deleterious degenerative processes that lead to cell death. Growing evidence suggests that selective blockade of the heterogeneous subunits that comprise the NMDA receptor may enable better control of ...

journal_title：Neurochemistry international

authors： Choo AM,Geddes-Klein DM,Hockenberry A,Scarsella D,Mesfin MN,Singh P,Patel TP,Meaney DF

更新日期：2012-04-01 00:00:00

abstract：:In this paper, two different aspects of growth hormone neuroregulation during aging were considered. Twenty-month-old male rats had decreased growth hormone-releasing hormone mRNA levels and a slight reduction of somatostatin mRNA levels in the hypothalamus when compared to 8-month-old counterparts. Short-term adminis...

journal_title：Neurochemistry international

authors： De Gennaro Colonna V,Cella SG,Parenti M,Locatelli V,Cocchi D,Müller EE

更新日期：1994-07-01 00:00:00

abstract：:Brain slices from actively myelinating (26-28 days) quaking and normal littermates were dual-labeled with radioactive mannose and fucose for 2 h. Following the incubation myelin was isolated by sucrose density gradient centrifugation and the incorporation of sugars into the major myelinassociated glycoprotein (MAG) de...

journal_title：Neurochemistry international

authors： Konat G,Hogan EL,Leskawa KC,Gantt G,Singh I

更新日期：1987-01-01 00:00:00

abstract：:Recent in vitro studies have revealed that benzodiazepines, opiates, barbiturates and ethanol might influence GABA binding to CNS membrane sites. Further studies of such interactions might be helpful for explaining both the mechanisms of action of these psychoactive agents and the tolerance/dependence that might resul...

journal_title：Neurochemistry international

authors： Defeudis FV

更新日期：1983-01-01 00:00:00

abstract：:Apart from acetyl-choline (Ach), adenosine-5'-trisphosphate (ATP) is thought to play a role in neuromuscular function, however little information is available on its cellular physiology. As such, effects of ATP and adenosine on contractility of mice diaphragmatic and skeletal muscles (m. extensor digitorum longa-MEDL)...

journal_title：Neurochemistry international

authors： Grishin SN,Teplov AY,Galkin AV,Devyataev AM,Zefirov AL,Mukhamedyarov MA,Ziganshin AU,Burnstock G,Palotás A

更新日期：2006-12-01 00:00:00

abstract：:The ventral pallidum (VP) is a critical component of the basal ganglia neurocircuitry regulating learning and decision making; however, its precise role in controlling associative learning of environmental stimuli conditioned to appetitive or aversive outcomes is still unclear. Here, we investigated the expression of ...

journal_title：Neurochemistry international

authors： Macpherson T,Mizoguchi H,Yamanaka A,Hikida T

更新日期：2019-06-01 00:00:00

abstract：:Alzheimer's disease (AD) is defined both by its progressive cognitive deterioration and hallmark increase in neuronal Aβ plaque formation. However, many of the underlying neurobiological facets of this disease are still being elucidated. Previous research has demonstrated that production of neuronal hydrogen sulfide (...

journal_title：Neurochemistry international

authors： He XL,Yan N,Zhang H,Qi YW,Zhu LJ,Liu MJ,Yan Y

更新日期：2014-02-01 00:00:00

abstract：:Five glutamate transporter genes have been identified; two of these (EAAT3 and EAAT4) are expressed in neurons and are predominantly confined to the membranes of cell bodies and dendrites. At an ultrastructural level, glutamate transporters have been shown to surround excitatory synapses in hippocampus and cerebellum ...

journal_title：Neurochemistry international

authors： Otis TS,Brasnjo G,Dzubay JA,Pratap M

更新日期：2004-09-01 00:00:00

abstract：:Gap junctions are transcellular pathways that enable a dynamic metabolic coupling and a selective exchange of biological signaling mediators. Throughout the course of the brain development these intercellular channels are assembled into regionally and temporally defined patterns. The present review summarizes the poss...

journal_title：Neurochemistry international

authors： Fróes MM,Menezes JR

更新日期：2002-11-01 00:00:00

abstract：:Serotonin2C receptor (5-HT2C) agonists are promising drugs for the treatment of neuropsychiatric diseases. However, their effect is not completely understood in part because they possibly affect several neurobiological networks simultaneously. We studied the effect of the 5-HT2C receptor agonist WAY-163909 (0.3 and 3 ...

journal_title：Neurochemistry international

authors： Chagraoui A,Whitestone S,Baassiri L,Manem J,Di Giovanni G,De Deurwaerdère P

更新日期：2019-03-01 00:00:00

abstract：:It has been shown recently that the N-terminal domain of the dopamine transporter (DAT) plays a role in several transporter functions. Here we provide evidence for a possible cellular mechanism of how the N-terminus of dopamine transporter might be removed in vivo. We isolated a recombinant N-terminal protein region o...

journal_title：Neurochemistry international

authors： Franekova V,Baliova M,Jursky F

更新日期：2008-06-01 00:00:00

abstract：:Brain edema and the subsequent increase in intracranial pressure are the major neurological complications in fulminant hepatic failure (FHF). Brain edema in FHF is predominantly "cytotoxic" due principally to astrocyte swelling. It is generally believed that ammonia plays a key role in this process, although the mecha...

journal_title：Neurochemistry international

authors： Jayakumar AR,Rao KV,Murthy ChR,Norenberg MD

更新日期：2006-05-01 00:00:00