Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivo.

abstract：:Centella asiatica is claimed to have a neuroprotective effect; however, its ability to protect the cerebrum against damage in diabetes has never been identified. The aims were to identify the possibility that C. asiatica ameliorates inflammation, oxidative stress, and apoptosis in the cerebrum in diabetes. C. asiatica...

journal_title：Inflammopharmacology

authors： Giribabu N,Karim K,Kilari EK,Nelli SR,Salleh N

更新日期：2020-12-01 00:00:00

abstract：AIM:Activation of sphingosine kinase (SK) is a key response to many inflammatory processes. The present studies test the hypothesis that an orally available SK inhibitor, ABC294640, would be effective in rodent models of Crohn's disease. METHODS:Trinitrobenzene sulfonic acid (TNBS) was administered rectally to mice an...

journal_title：Inflammopharmacology

authors： Maines LW,Fitzpatrick LR,Green CL,Zhuang Y,Smith CD

更新日期：2010-04-01 00:00:00

abstract：:There is a growing body of evidence that plant polyphenols such as resveratrol, anthocyanins, catechins, and terpenes like taxol are effectively used in the treatment of chronic conditions including cancer, Alzheimer, Parkinsonism, diabetes, aging, etc. The link between oxidative stress and inflammation is well accept...

journal_title：Inflammopharmacology

authors： Afzal M,Safer AM,Menon M

更新日期：2015-08-01 00:00:00

abstract：:The ulcerogenic effect of rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on the gastrointestinal mucosa was investigated in the presence of a low dose of indomethacin. Indomethacin at 3 mg/kg did not cause any damage in both the stomach and small intestine, despite inhibiting prostaglandin (PG) production....

journal_title：Inflammopharmacology

authors： Yokota A,Taniguchi M,Tanaka A,Takeuchi K

更新日期：2005-01-01 00:00:00

abstract：:Stress is a reflex response, both psychological and physiological, of the body to a difficult situation that requires adaptation. Stress is at the intersection of the objective event and the subjective event. The physiological mechanisms involved in chronic stress are numerous and can contribute to a wide variety of d...

journal_title：Inflammopharmacology

authors： Nessaibia I,Fouache A,Lobaccaro JA,Tahraoui A,Trousson A,Souidi M

更新日期：2019-02-01 00:00:00

abstract：:Methyl gallate is a gallotannin widely distributed in nature. Previous studies have demonstrated its antioxidant, anti-inflammatory, antimicrobial and anti-tumor activities. In the present study, the activity of methyl gallate on experimental models of inflammatory bowel disease has been investigated. Experimental col...

journal_title：Inflammopharmacology

authors： Anzoise ML,Basso AR,Del Mauro JS,Carranza A,Ordieres GL,Gorzalczany S

更新日期：2018-06-01 00:00:00

abstract：:The side effects of NSAIDs are equally evident in the stomach and the small bowel. The latter is increasingly seen as being clinically significant, contributing substantially to the iron-deficiency anaemia that is so common in patients with rheumatoid arthritis. Furthermore, NSAID-enteropathy may be associated with li...

journal_title：Inflammopharmacology

authors： Hotz-Behofsits CM,Walley MJ,Simpson R,Bjarnason IT

更新日期：2003-01-01 00:00:00

abstract：:The up-regulation of angiotensin II AT1 receptors has been implicated as a major mediator in the development of hypertension and progressive nephropathy in experimental diabetes. In spite of the documented potential of garlic treatments in ameliorating diabetic complications, the possible involvement of the angiotensi...

journal_title：Inflammopharmacology

authors： Mansour MH,Al-Qattan K,Thomson M,Ali M

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of Azadirachta indica leaf extracts against Salmonella typhimurium-induced inflammation in BALB/c mice. DESIGN:Qualitative tests of A. indica leaf extracts were conducted for screening of various phytochemicals. The antiinflammatory potential of A. indica leaf extracts on S. typhimu...

journal_title：Inflammopharmacology

authors： Koul A,Bharrhan S,Singh B,Rishi P

更新日期：2009-02-01 00:00:00

abstract：:Based on a unifying theory presented here, it is predicted that the immune defects resulting in chronic inflammation rather than effective immune responses could be rectified by the therapeutic use of agents prepared from micro-organisms. With appropriate molecular patterns, these should be able to induce protective i...

journal_title：Inflammopharmacology

authors： Bottasso O,Docena G,Stanford JL,Grange JM

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The present study aimed to evaluate the anti-inflammatory and analgesic activities of the ginsenoside metabolite compound K (CK) and its mechanisms. METHODS:Mice model of xylene-induced ear swelling and rat model of carrageenan-induced paw swelling were used to evaluate the effect of CK on acute inflammation...

journal_title：Inflammopharmacology

authors： Chen J,Si M,Wang Y,Liu L,Zhang Y,Zhou A,Wei W

更新日期：2019-02-01 00:00:00

abstract：:To clarify roles of H2S in regulation of gastric circulation, we investigated effects of NaHS, a H2S donor, on tension of isolated rat gastric artery and gastric mucosal blood flow in rats. In the precontracted ring preparations, NaHS caused contraction and relaxation at low and high concentrations, respectively. The ...

journal_title：Inflammopharmacology

authors： Kubo S,Kajiwara M,Kawabata A

更新日期：2007-12-01 00:00:00

abstract：AIMS:To compare methodological aspects of the impact of different classification procedures used in three phases of a twin study examining genetic factors in the aetiopathogenesis of rheumatoid arthritis (RA). METHODS:We have previously reported the results of a study of the aetiopathogenesis of RA based on the Austra...

journal_title：Inflammopharmacology

authors： Bellamy N,Duffy DL,Sambrook P,Buchanan RR,Brooks PM,Dunckley H,Healey SC,Mason S,Martin NG

更新日期：1998-01-01 00:00:00

abstract：:TRP channels have been discovered as a specialized group of somatosensory neurons involved in the detection of noxious stimuli. Desensitization of TRPV1 located on dorsal root and trigeminal ganglia exhibits analgesic effect and makes it potential therapeutic target for treatment of neuropathic pain. With this backgro...

journal_title：Inflammopharmacology

authors： Marwaha L,Bansal Y,Singh R,Saroj P,Sodhi RK,Kuhad A

更新日期：2016-12-01 00:00:00

abstract：:Ischemia/reperfusion (I/R) damages gastric mucosa via reactive oxygen species (ROS) activity. ROS was reportedly produced through angiotensin II stimulation in tissues such as kidney, heart and brain. To determine whether AT1 receptor plays a role in gastric mucosal damage, we examined the effect of AT1 receptor block...

journal_title：Inflammopharmacology

authors： Nakagiri A,Sunamoto M,Murakami M

更新日期：2007-08-01 00:00:00

abstract：:Previous reports suggest flavonoids as potent analgesic compounds. Based on these observations, the present study investigated the antinociceptive action of flavonol, 3', 4'-dimethoxy flavonol, 6, 3'-dimethoxy flavonol, 7, 2'-dimethoxy flavonol, and 7, 3'-dimethoxy flavonol and the possible mechanisms involved in thes...

journal_title：Inflammopharmacology

authors： Sayeli V,Nadipelly J,Kadhirvelu P,Cheriyan BV,Shanmugasundaram J,Subramanian V

更新日期：2019-12-01 00:00:00

abstract：:Allanblackia gabonensis (Guttiferae) is a plant used in the African traditional medicine as remedies against pain, rheumatism, inflammations. In the present work, the analgesic effect of aqueous extract has been evaluated using acetic acid, formalin, hot-plate test, tail immersion and paw-pressure test. The anti-infla...

journal_title：Inflammopharmacology

authors： Ymele EV,Dongmo AB,Dimo T

更新日期：2013-02-01 00:00:00

abstract：:Most of the gastroprotective drugs which had been marketed in Japan were considered to have insufficient rationale for use as ulcer treatments. Such drugs may have a crucial role in maintaining mucosal integrity by the mechanisms other than inhibition of acid secretion. We re-evaluated the effect of gastroprotective d...

journal_title：Inflammopharmacology

authors： Higuchi K,Watanabe T,Tanigawa T,Shiba M,Tominaga K,Fujiwara Y,Oshitani N,Arakawa T

更新日期：2007-02-01 00:00:00

abstract：:P38 mitogen-activated protein kinase (p38 MAPK), a tissue inflammatory factor can be activated under oxidative stress and in conditions associated with hyperglycemia. Gingerol containing various natural herbs has been extensively studied for its pharmacological actions both in reducing the inflammation and as immunity...

journal_title：Inflammopharmacology

authors： Song S,Dang M,Kumar M

更新日期：2019-12-01 00:00:00

abstract：:The Maytenus genus is a member of the Celastraceae family. Numerous medicinal uses were assigned to species of this genus, with the use of roots, bark, and leaves for the treatment of gastric ulcers, as anti-inflammatory, analgesic, antiallergic, antitumor, among others. Several studies have demonstrated that natural ...

journal_title：Inflammopharmacology

authors： Veloso CC,Oliveira MC,Rodrigues VG,Oliveira CC,Duarte LP,Teixeira MM,Ferreira AVM,Perez AC

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Hydroxychloroquine (HCQ) is a widely prescribed medication to patients with systemic lupus erythematosus (SLE), with potential anti-inflammatory effects. This study was performed to investigate the efficacy of HCQ therapy by serial assessment of disease activity and serum levels of proinflammatory cytokines ...

journal_title：Inflammopharmacology

authors： Monzavi SM,Alirezaei A,Shariati-Sarabi Z,Tavakol Afshari J,Mahmoudi M,Dormanesh B,Jahandoost F,Khoshdel AR,Etemad Rezaie A

更新日期：2018-10-01 00:00:00

abstract：:Regular moderate wine consumption is often associated with reduced morbidity and mortality from to a variety of chronic diseases in which inflammation is a root cause. Wine comes in a wide variety of styles that contain quite different ethanol and polyphenol contents. Controversy remains as to whether the alcohol or p...

journal_title：Inflammopharmacology

authors： Walzem RL

更新日期：2008-12-01 00:00:00

abstract：:A small GTPase, Rac1, is recognized as an important modulator of the inflammatory responses to bacterial lipopolysaccharide (LPS) by affecting the processes of phospholipase C activation. The activation of Rac1 involves the exchange of GDP for GTP and is catalyzed by the guanine nucleotide exchange factors (GEFs). Her...

journal_title：Inflammopharmacology

authors： Slomiany BL,Slomiany A

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The role of angiotensin converting enzyme inhibitors on the inflammation process has been demonstrated previously. In the present study, the effects of captopril on lung injury induced by lipopolysaccharide (LPS) were investigated. METHODS:Control, LPS, 12.5, 25 and 50 mg/kg captopril-treated before LPS adm...

journal_title：Inflammopharmacology

authors： Boskabadi J,Askari VR,Hosseini M,Boskabady MH

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:Retinoic Acid Related Orphan Nuclear Receptor gamma T (RORγT) is a lineage specifying transcription factor for IL-17 expressing cells, which may contribute to the pathogenesis of Inflammatory Bowel Disease (IBD). VPR-254 is a selective in vitro inhibitor of RORγT. AIMS:The main goals of our study were two...

journal_title：Inflammopharmacology

authors： Fitzpatrick LR,Small J,O'Connell R,Talbott G,Alton G,Zapf J

更新日期：2020-04-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the anti-inflammatory effect of thymol in acetic acid-induced rat colitis through inhibiting the NF-κB signaling pathway. METHODS:Colitis was induced by intra-rectal administration of 2 mL of diluted acetic acid (4%) solution using a flexible plastic rubber catheter in ...

journal_title：Inflammopharmacology

authors： Chamanara M,Abdollahi A,Rezayat SM,Ghazi-Khansari M,Dehpour A,Nassireslami E,Rashidian A

更新日期：2019-12-01 00:00:00

abstract：:Gout, the most prevalent inflammatory arthritis worldwide, released interleukin-1β (IL-1β) and Cathepsin B inflammatory mediators that constitute the hallmark of the disease. Herein we aimed to investigate whether procyanidin B2 (PCB2), a natural dietary compound, can suppress MSU crystals-stimulated gouty inflammatio...

journal_title：Inflammopharmacology

authors： Qiao CY,Li Y,Shang Y,Jiang M,Liu J,Zhan ZY,Ye H,Lin YC,Jiao JY,Sun RH,Zhang ZH,Piao MH,Wu YL,Nan JX,Lian LH

更新日期：2020-12-01 00:00:00

abstract：:Acute lung injury (ALI) and acute kidney injury (AKI) are major causes of sepsis-induced mortality. The objective of the study is to evaluate the effect of tocilizumab (TCZ), an IL-6 receptor inhibitor, in sepsis-induced ALI and AKI using the cecal ligation and puncture (CLP) rat model of sepsis. Clinical and experime...

journal_title：Inflammopharmacology

authors： Ibrahim YF,Moussa RA,Bayoumi AMA,Ahmed AF

更新日期：2020-02-01 00:00:00

abstract：:Central nervous system (CNS) has a completely separate immune system that communicates with the neurons by small molecules called cytokines. Cytokines are involved in many crucial processes in neuron including cell metabolism and neurotransmitter synthesis. It has been reported that cytokine imbalance is involved in t...

journal_title：Inflammopharmacology

authors： Al-Amin MM,Uddin MM,Rahman MM,Reza HM,Rana MS

更新日期：2013-12-01 00:00:00

abstract：:Nicotine mediates some of the injurious effects caused by consuming tobacco products. The aim of this work is to investigate the protective effects of Mentha spicata extract (ME) supplementation on the testis and brain of nicotine-induced oxidative damage rats. ME extract showed interesting hydrogen peroxide-scavengin...

journal_title：Inflammopharmacology

authors： Saad AB,Rjeibi I,Brahmi N,Elaloui E,Zouari N

更新日期：2020-08-01 00:00:00