Abstract:
AIM:The aim of this study was to explore the service for patients with inflammatory bowel disease taking or having taken azathioprine or 6-mercaptopurine in the last three years, at two District General Hospitals within the same Trust. BACKGROUND:Published data confirm that the use of azathioprine and 6-mercaptopurine is effective in the control of inflammatory bowel disease. However, there are inconsistencies in dosing regimes, blood monitoring and duration of therapy. Regimes used have been largely based on clinicians' personal preference leading to inconsistencies in practice. METHODS:A questionnaire, designed to elicit the experience of treatment regimes, blood monitoring and access to information was sent to 130 patients taking or having taken azathioprine or 6-mercaptopurine in the last three years. A further questionnaire was sent to 94 general practitioners and interviews were conducted with 10 hospital doctors initiating treatment. RESULTS:The study demonstrated lack of clarity in the prescribing methods, the monitoring regimes being offered, variation in information given to patients and consequent patient knowledge. CONCLUSION:Azathioprine and 6-mercaptopurine are increasingly being used successfully in inflammatory bowel disease, sparing the use of steroids and maintaining remission over a longer period. A review of the current literature has informed and made possible a suggested blood-monitoring regime. RELEVANCE TO CLINICAL PRACTICE:The adoption of a protocol-led service, managed by the nurse specialist, incorporating guided self-management by patients should be considered. A shared-care approach with the patient and general practitioner with rapid access to secondary care would provide a robust system.
journal_name
J Clin Nursjournal_title
Journal of clinical nursingauthors
Holbrook Kdoi
10.1111/j.1365-2702.2006.01670.xsubject
Has Abstractpub_date
2007-08-01 00:00:00pages
1427-34issue
8eissn
0962-1067issn
1365-2702pii
JCN1670journal_volume
16pub_type
杂志文章abstract:AIMS AND OBJECTIVES:To explore staff reactions to residents' behaviour consisting in exposing their genitals in public, and to differentiate between what is perceived as common practice (what most staff do) and best practice (the best possible approach). BACKGROUND:The presence of inappropriate sexual behaviours (ISBs...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,多中心研究
doi:10.1111/jocn.14952
更新日期:2019-10-01 00:00:00
abstract:AIM:This paper investigated the possible predictive and mediating determinates of quality of life in this often forgotten population, focusing specifically on the role of sociodemographics, mental impairments, coping mechanisms, resilience and hope on subjective quality of life. BACKGROUND:The family members of surviv...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2010.03664.x
更新日期:2011-07-01 00:00:00
abstract:AIMS AND OBJECTIVES:The aim of this study was to assess the effect of a supportive educational intervention developed based on the Orem's self-care theory on the self-care ability of patients with myocardial infarction. BACKGROUND:Patients with cardiovascular disease suffer from the lack of knowledge about the disease...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocn.12775
更新日期:2015-06-01 00:00:00
abstract:AIMS:To estimate the proportion of nurses in Hungary who intend to change their profession or want to migrate abroad; to compare the proportion of nurses who intend to leave nursing in Hungary and in selected European countries; and to describe factors that predict nurses' intent to work in their current job another ye...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2010.03405.x
更新日期:2011-03-01 00:00:00
abstract:AIMS AND OBJECTIVES:The purpose of this study was to explore the impact of chronic pain on the partner and family of a person with chronic pain. BACKGROUND:Chronic pain impacts not only on the individual but also their partner and/or other family members. Families of people with chronic pain have reported feeling powe...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2012.04215.x
更新日期:2012-12-01 00:00:00
abstract:AIM:To develop a tool that would allow a fatigue assessment for chronic obstructive pulmonary disease patients that nurses could use irrespective of the level of response available from the patient. BACKGROUND:It is important that nurses are able to undertake a full assessment of chronic obstructive pulmonary disease ...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2007.01945.x
更新日期:2007-07-01 00:00:00
abstract::Newly admitted residents in long-term care facilities are particularly vulnerable to depression and the early recognition and treatment of depression is therefore crucial around the time of admission to a home. Staff from 30 nursing and residential homes were asked to assess newly admitted residents for depression usi...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1046/j.1365-2702.2000.00390.x
更新日期:2000-05-01 00:00:00
abstract:AIMS AND OBJECTIVES:To analyse the sensitivity and specificity of clinical indicators of ineffective airway clearance in children with congenital heart disease and to identify the indicators that have high predictive power. BACKGROUND:The precise establishment of nursing diagnoses has been found to be one of the facto...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:AIMS AND OBJECTIVES:To study the combination of personality and interpersonal behaviour of staff nurses in general hospitals in relation to burnout and its separate dimensions. BACKGROUND:More research on the individual factors contributing to the development of burnout is needed to improve the risk profile of nursing...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.13808
更新日期:2017-12-01 00:00:00
abstract:AIM:The object of this study was to find out which self-care activities patients with diabetes perform to prevent diabetic foot syndrome (DFS) and to look for differences between patient groups (diabetes education and foot at risk). BACKGROUND:Besides the importance of screening patients at risk to develop a DFS and t...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2008.02352.x
更新日期:2008-11-01 00:00:00
abstract::The global and urgent response to the COVID-19 pandemic has forced healthcare systems to broadly adopt technologies that allow care and services to shift virtually. This includes video conferencing, wearables, and telemedicine applications (King, 2020; Morris, 2020; Weiss et al., 2020); all of which lower the number o...
journal_title:Journal of clinical nursing
pub_type: 社论
doi:10.1111/jocn.15581
更新日期:2020-12-01 00:00:00
abstract:AIM AND OBJECTIVES:To determine the relationship between cultural sensitivity and perceived stress of nurses working at Kilis State Hospital. BACKGROUND:As foreigners live in and visit Turkey for various reasons, it is essential to provide culturally appropriate healthcare. DESIGN:Descriptive and cross-sectional desi...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.12982
更新日期:2015-12-01 00:00:00
abstract:AIMS AND OBJECTIVES:To investigate the associations between self-reported falls and health complaints, among persons aged 75 years and older living at home, and to investigate gender differences in the associations. BACKGROUND:There are several studies concerned with risk factors for falling, and others related to hea...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.12279
更新日期:2013-10-01 00:00:00
abstract:AIMS AND OBJECTIVES:To describe fear, the threats causing fear and the occurrence of fear among emergency department nursing staff and physicians. BACKGROUND:The emergency department is a challenging workplace where the staff is often confronted by factors that cause fear. DESIGN:A cross-sectional study. METHODS:A s...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,多中心研究
doi:10.1111/jocn.13633
更新日期:2017-10-01 00:00:00
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journal_title:Journal of clinical nursing
pub_type: 杂志文章,评审
doi:10.1111/jocn.14211
更新日期:2018-03-01 00:00:00
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journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1046/j.1365-2702.2001.00506.x
更新日期:2001-07-01 00:00:00
abstract:AIMS AND OBJECTIVES:To explore the experiences and perceptions of hospital staff caring for dying patients in a dedicated patient/family room (named Lotus Room). BACKGROUND:Dying in hospital is a common outcome for people across the world. However, noise and activity in acute environments present barriers to quality e...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.12845
更新日期:2015-08-01 00:00:00
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journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2008.02738.x
更新日期:2009-08-01 00:00:00
abstract::A purposive and convenience sample of 16 women and four men receiving informal and formal care for their activities of daily living either at home or institutions in Southeast Washington, USA was interviewed. Qualitative findings related to asking for help, getting and receiving help, interpersonal aspects of receivin...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1046/j.1365-2702.2001.00484.x
更新日期:2001-05-01 00:00:00
abstract::Drug administration is an integral part of the nurse's role. Responsibility for correct administration of medication rests with the nurse, yet medication errors are a persistent problem associated with nursing practice. This review examines what constitutes a medication error and documents contributory factors in medi...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2702.1999.00284.x
更新日期:1999-09-01 00:00:00
abstract:AIM AND OBJECTIVE:To identify training strategies and determine how registered health and social care practitioners change their practice after Mental Capacity Act training. DESIGN:Narrative literature review. DATA SOURCES:Seventeen databases were searched up to December 2019: CINAHL, Social Care Online, PubMed, Soci...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,评审
doi:10.1111/jocn.15256
更新日期:2020-07-01 00:00:00
abstract:AIMS AND OBJECTIVES:To explore service provision for Victorian regional refugee families from the perspective of maternal and child health nurses. BACKGROUND:Increasingly, more families from a refugee background are resettling in regional Victoria. The refugee journey has significant effect on families. Refugee famili...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.14277
更新日期:2018-09-01 00:00:00
abstract:AIMS AND OBJECTIVES:To explore the assumption that people with ID are unable to communicate effectively about pain by examining the extent to which they were reported as using language and behaviour that was readily understandable to others to communicate pain as distinct from distress. BACKGROUND:The healthcare needs...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2012.04269.x
更新日期:2013-07-01 00:00:00
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journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2011.03884.x
更新日期:2012-03-01 00:00:00
abstract:AIMS AND OBJECTIVES:To assess the impact of a Twitterchat focusing on antimicrobial resistance and it is feasibility for integration within a nursing prelicensure research methods class. BACKGROUND:Antimicrobial resistance is one of the greatest threats to global health and food security. Consequently, developing a gl...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.15185
更新日期:2020-07-01 00:00:00
abstract:AIMS AND OBJECTIVES:(1) To develop an insight into the opportunities and barriers to nurse prescribing for a case study of children's nurses. (2) To consider the implications of independent nurse prescribing for children's nurses and the potential for nurse prescribing to be developed in acute children's care settings....
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/j.1365-2702.2006.01585.x
更新日期:2007-03-01 00:00:00
abstract:AIMS AND OBJECTIVES:To identify person-centred care as an intervention in controlled trials, where patients had been involved as a partner, and to describe the outcomes of these studies. BACKGROUND:The notion of person-centred care asserts that patients are persons and partners in care and should not be reduced to the...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,评审
doi:10.1111/jocn.12039
更新日期:2013-02-01 00:00:00
abstract:AIMS AND OBJECTIVES:To determine the effect of the amount of rice carbohydrates consumed during mealtime on the extent of decrease in postprandial blood pressure in older people with postprandial hypotension. BACKGROUND:The incidence of postprandial hypotension is as high as 74% in older people with hypertension. DES...
journal_title:Journal of clinical nursing
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocn.12864
更新日期:2015-08-01 00:00:00
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journal_title:Journal of clinical nursing
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2702.2009.03010.x
更新日期:2010-06-01 00:00:00
abstract:AIMS AND OBJECTIVES:To explore patients', families' and health professionals' experiences of a long-stay patient in an intensive care unit. BACKGROUND:The fast-paced technologically driven intensive care unit environment, designed for a short patient stay, supports the provision of complex physiologically focused care...
journal_title:Journal of clinical nursing
pub_type: 杂志文章
doi:10.1111/jocn.14184
更新日期:2018-06-01 00:00:00