Abstract：
:The incidence of gastroschisis appears to be rising in developed nations, with epidemiological studies indicating association with young maternal age and smoking. Is there an association between maternal smoking and the development of complicated gastroschisis? A retrospective population-based review of all cases of gastroschisis over 11 years was conducted in three Canadian provinces. Complicated cases were defined as those with an associated intestinal atresia or other vascular compromise of the bowel, those requiring a prolonged time to full enteral feeding (>42 days). Univariate and multivariate regression analyses were conducted. Fifty-four cases of gastroschisis were treated. Seventeen patients had complicated gastroschisis (CG). 47.1% of infants were born to smoking mothers; of those 56.25% were in the CG group. On univariate analysis statistically significant associations with complicated cases were young maternal age (<19 years) (OR = 6.0, CI: 1.3, 28.1), low maternal weight gain (<12 kg) (OR = 4.6, CI: 2.5, 8.5), low birth weight (<2,400 g), (OR = 7.7, CI: 2.0, 28.9), and gestational age under 36 weeks (OR = 11.0, CI: 2.6, 46.2). Seven of 24 cases involving maternal smoking developed atresias or vascular intestinal compromise versus 4 of 27 cases with no maternal smoking, with an odds ratio of 2.1 (CI: 0.60, 7.2). On multivariate analysis, atresias and vascular compromise remained significantly associated with young maternal age, low gestational age and low 1-min Apgar score. Although a positive trend is seen, no statistically significant relationship between maternal smoking and the development of complicated gastroschisis was found. Further clinical and epidemiologic studies are needed to validate our findings.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Zamakhshary M,Yanchar NLdoi
10.1007/s00383-007-1926-6subject
Has Abstractpub_date
2007-09-01 00:00:00pages
841-4issue
9eissn
0179-0358issn
1437-9813journal_volume
23pub_type
杂志文章abstract：PURPOSE:The use of general anesthesia in young children has come under increasing scrutiny due to its potential long-term neurotoxic effects. Meanwhile, regional anesthesia for surgical procedures in neonates has many advantages, including preservation of respiratory status and faster return to feeding. We describe the...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-4027-6
更新日期：2017-03-01 00:00:00
abstract：PURPOSE:The aim of this study was to determine if there is a difference between complications for totally implantable central venous catheters (ports) and tunnelled external central venous catheters (external CVCs) that result in early removal of the central venous catheter (CVC) in children and adolescents with acute ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3213-4
更新日期：2012-12-01 00:00:00
abstract：:Congenital hepatic cysts are rare lesions of infancy. While operative management and outcomes have been extensively studied in adult patients with hepatic cysts, data in pediatric patients are limited. We discuss our experience in an infant and review relevant literature regarding operative technique and surgical outc...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-013-3312-x
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:Surgery of the inguinal canal is very common in infancy. Occasionally, injury of the bladder may occur with severe consequences. The aim of this paper was to warn young surgeons of this serious complication. METHODS:During the last 2 years, we observed four cases of bladder injury following surgery on inguinal...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-010-2707-1
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:Bone morphogenetic proteins (BMPs) are a group of growth factors that are implicated in intestinal growth, morphogenesis, differentiation, and homeostasis. The role of the BMP signaling cascade in stimulation of cell proliferation after massive small bowel resection is unknown. The purpose of this study was to ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3829-2
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Children with intussusception require rapid and accurate diagnosis to enable timely intervention for satisfactory outcome. Ultrasonography is the recommended standard diagnostic modality; however, abdominal radiography (AR) is still used as an initial investigation. The aim of this study was to investigate t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3817-6
更新日期：2016-01-01 00:00:00
abstract：:Recurrent or chronic abdominal pain can be a challenging problem when conventional diagnostic studies fail to identify the cause. It is estimated that up to one-third of children suffer from abdominal pain, and in this population recurrent pain can be even more challenging. Although recurrent right lower quadrant (RLQ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1632-1
更新日期：2006-03-01 00:00:00
abstract：:The factors that affect survival in patients with stage 4 neuroblastoma vary. Several prospective and retrospective studies have provided conflicting conclusions regarding the benefit of combining aggressive chemotherapy with complete surgical resection. We analyzed our experience to evaluate the effect of complete su...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1353-x
更新日期：2005-02-01 00:00:00
abstract：:Cystic teratoma of the pancreas is an extremely rare entity: only 11 cases have been described so far in the world literature. We report the 12th case, in a 4-month-old girl. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00183759
更新日期：1996-03-01 00:00:00
abstract：BACKGROUND:Pediatric burn injuries are one of the leading causes of preventable morbidity and mortality in Sub-Saharan Africa. Research on the complex system of social, economic and cultural factors contributing to burn injuries in this setting is much needed. METHODS:We conducted a prospective questionnaire-based ana...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3761-5
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:Hirschsprung disease (HSCR) has previously been associated with increased mortality. The aim of this study was to assess mortality in patients with Hirschsprung disease in a population-based cohort. METHODS:This was a nationwide, population-based cohort study. The study exposure was HSCR and the study outcome ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-017-4150-z
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Pediatric patients with medically refractory ulcerative colitis (UC) often undergo an initial subtotal colectomy end ileostomy (STC-I). The role of fecal diversion in the subsequent completion proctectomy/ileal-pouch anal anastomosis (CP-IPAA) remains controversial. METHODS:A multi-institutional retrospecti...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-019-04440-1
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:Evaluate the management of hydrocephalus in pediatric patients in the Eastern Democratic Republic of Congo by a general surgeon. METHODS:Retrospective review of a single institution in the province of North Kivu. Patient charts and surgical notes were reviewed from 2003 to 2016. RESULTS:116 procedures were pe...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4238-0
更新日期：2018-04-01 00:00:00
abstract：:Lipiodol, a stable iodine addition product of fatty ethyl esters derived from poppyseed oil, has been used as a vehicle for targeted cytotoxic or radiotherapeutic treatment in adults with unresectable hepatocellular carcinoma and in a few children with advanced hepatoblastoma (HB). Prolonged retention of lipiodol by t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100004
更新日期：2001-11-01 00:00:00
abstract：:Juvenile papillomatosis (JP) is a rare benign, proliferative breast tumor in children. We observed a 9-year-old girl with a large soft-tissue mass at the lower outer quadrant of the left breast. Ultrasonography showed an ill-defined, inhomogeneous mass with numerous small, hypoechoic areas. The tumor was completely ex...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000462
更新日期：2001-03-01 00:00:00
abstract：:A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01194812
更新日期：1997-01-01 00:00:00
abstract：:At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1839-9
更新日期：2007-02-01 00:00:00
abstract：:The Malone antegrade enema (MACE) and the caecostomy button (CB) are two methods of achieving colonic lavage in constipated children with faecal soiling. We reviewed our experience with the MACE and CB, aiming to compare results, complications, and outcomes. Between June 1998 and August 2002, 37 children (15 boys) und...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1220-9
更新日期：2004-07-01 00:00:00
abstract：:"Variants of Hirschsprung's disease" are conditions that clinically resemble Hirschsprung's disease (HD), despite the presence of ganglion cells in rectal suction biopsies. The diagnosis and management of these patients can be challenging. Specific histological, immunohistochemical and electron microscopic investigati...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-013-3351-3
更新日期：2013-09-01 00:00:00
abstract：AIM OF THE STUDY:The high morbidity and mortality in congenital diaphragmatic hernia (CDH) is attributed to pulmonary hypoplasia and persistent pulmonary hypertension (PH). PH is characterized by increased pulmonary artery smooth muscle cell (SMC) proliferation, suppressed apoptosis as well as endothelial dysfunction. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3606-7
更新日期：2014-12-01 00:00:00
abstract：:It is unknown whether noncomplicated acute appendicitis cause bacterial translocation. In this study, we aimed to test development of the bacterial translocation in the patients who were operated for acute appendicitis. In this prospective study, 10 control patients who underwent elective operations because of other r...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1899-5
更新日期：2007-06-01 00:00:00
abstract：PURPOSE:This study evaluates the capacity of ultrasonography as a diagnostic method to confirm the proper positioning of central venous catheter (CVC) when compared to the current gold standard, chest radiography (CR). METHODS:A prospective study was performed including children from 0 to 14 incomplete years, who unde...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-020-04642-y
更新日期：2020-05-01 00:00:00
abstract：:Repair of recurrent tracheoesophageal fistula (TEF) after repair of congenital esophageal atresia continues to be a difficult problem. The most common re-operation for a recurrent TEF involves repair via a right thoracotomy and use of a flap as interposed tissue between the closure sites. Although several materials ha...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3255-7
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:We sought to determine the incidence and timing of testicular atrophy following inguinal hernia repair in children. METHODS:We used the TRICARE database, which tracks care delivered to active and retired members of the US Armed Forces and their dependents, including > 3 million children. We abstracted data on ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4255-z
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:The purpose of this study was to test the susceptibility of human hepatoblastoma and neuroblastoma cells to photodynamic diagnostics (PDD) and photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) as a photosensitizer. METHODS:Cell cultures of human hepatoblastoma (HuH6) and neuroblastoma (MHH-NB-11) ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2275-9
更新日期：2008-12-01 00:00:00
abstract：:New development in the vascular network is a significant process for the proliferation, as well as metastatic expand, of cancer cells that depends on a sufficient provider of oxygen and nutrients and the removal of waste products. New blood and lymphatic vessels form via step called angiogenesis and lymphangiogenesis....
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-013-3398-1
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:To describe the association of anorectal malformation (ARM) and spinal dysraphism (SD) in terms of impact on the management of SD and embryogenetic implications. METHODS:Patients with SD associated with (A) or without (B) ARM were included. The two groups were further divided into operated on (A1/B1) or not (A...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4104-5
更新日期：2017-08-01 00:00:00
abstract：:Minor degrees of exomphalos have been known to be associated with vitellointestinal duct anomalies. The most frequent association is Meckel's diverticulum. It is unusual for a fistula to be communicating directly with the exomphalos sac. We report five neonates that presented with a fistula on the exomphalos sac over ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-006-1699-3
更新日期：2006-07-01 00:00:00
abstract：:Interstitial cells of Cajal (ICCs) have been reported to play the role of a pacemaker in regulating bowel motility. The relationship between neurons and ICCs, however, remains unclear. Hirschsprung's disease (HD) is an ideal model for investigating this relationship. The operated specimens obtained from 6 short and 3 ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0931-z
更新日期：2003-06-01 00:00:00
abstract：:Surgical repair of acquired tracheo-esophageal fistula may result in tracheal stenosis or esophageal stricture. We used fistula with esophageal cuff as flap to repair the tracheal defect. Esophageal repair was performed by rotating ends through 90° in opposite direction. This technique offers excellent repair in a sin...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3498-6
更新日期：2014-05-01 00:00:00
