Declines in dietary macronutrient intake in persons with HIV infection who develop depression.

Abstract:

BACKGROUND:The effect of depression on dietary intake has not, to our knowledge, been examined in persons with HIV infection. METHODS:We conducted a longitudinal analysis of participants in the Nutrition for Healthy Living Study (NFHL). We measured changes in dietary macronutrient intake in participants who developed depression and, using multiple regression analysis, compared the changes with a control group of patients who did not become depressed. RESULTS:Ninety patients developed depression during the observation period, and we compared these with 152 non-depressed controls. The two groups had similar age and body mass index (BMI) at baseline, but those who developed depression were more likely to be female, less educated and had lower incomes. After adjustment, compared with non-depressed participants, those who developed depression had significantly greater decreases in the following daily intakes: total energy (-341 kcal, P = 0.006), protein (-12.3 g, P = 0.02), total fat (-18.5 g, P = 0.008), carbohydrate (-36.8 g, P = 0.02), total fibre (-4.3 g, P = 0.001) and saturated fat (-6.7 g, P = 0.01). There were no significant differences in the daily intakes of simple sugars and long-chain n-3 fatty acids, or BMI. CONCLUSION:Depression is associated with decreases in total daily energy intake and in six of the eight dietary components we measured. Clinicians should be aware that depression-associated nutritional deficiencies may complicate the care of persons with HIV.

journal_name

Public Health Nutr

journal_title

Public health nutrition

authors

Isaac R,Jacobson D,Wanke C,Hendricks K,Knox TA,Wilson IB

doi

10.1017/S1368980007000067

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

124-31

issue

2

eissn

1368-9800

issn

1475-2727

pii

S1368980007000067

journal_volume

11

pub_type

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