Rapid recovery from sevoflurane and desflurane with hypercapnia and hyperventilation.

Abstract:

BACKGROUND:Hypercapnia with hyperventilation shortens the time between turning off the vaporizer (1 MAC) and when patients open their eyes after isoflurane anesthesia by 62%. METHODS:In the present study we tested whether a proportional shortening occurs with sevoflurane and desflurane. RESULTS:Consistent with a proportional shortening, we found that hypercapnia with hyperventilation decreased recovery times by 52% for sevoflurane and 64% for desflurane (when compared with normal ventilation with normocapnia). CONCLUSION:Concurrent hyperventilation to rapidly remove the anesthetic from the lungs and rebreathing to induce hypercapnia can significantly shorten recovery times and produce the same proportionate decrease for anesthetics that differ in solubility.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Sakata DJ,Gopalakrishnan NA,Orr JA,White JL,Westenskow DR

doi

10.1213/01.ane.0000265849.33203.60

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

79-82

issue

1

eissn

0003-2999

issn

1526-7598

pii

105/1/79

journal_volume

105

pub_type

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