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Antimicrobial activity of rationally designed amino terminal modified peptides.

Abstract：

:Series of short amino terminal modified cationic peptides were designed and synthesized. All of the synthesized compounds were tested against gram-positive as well as gram-negative bacterial strain. Some of the compounds exhibit potent antibacterial activity and no hemolytic activity even at high dose level (1000 microg/mL) in mammalian erythrocytes was observed.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Bisht GS,Rawat DS,Kumar A,Kumar R,Pasha S

doi

10.1016/j.bmcl.2007.05.015

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

4343-6

issue

15

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(07)00566-5

journal_volume

17

pub_type

杂志文章

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