Endoscopic palliation of pancreatic cancer.

abstract：:Dramatic refinements in CT technology are resulting in improved evaluation of the liver, pancreas, and gastrointestinal tract. Further clinical trials are necessary to compare the relative merits of CT versus MR imaging and endoscopic ultrasonography in a wide variety of gastrointestinal diseases. ...

journal_title：Gastroenterology clinics of North America

authors： Zeman RK,Silverman PM,Cooper C,Weltman DI,Ascher SM,Patt RH

更新日期：1995-06-01 00:00:00

abstract：:Rarely do otherwise safe drugs administered at recommended doses produce liver damage that may progress to liver failure and death. Because we are generally unable to identify the patients most susceptible to this "idiosyncratic" form of toxicity, many potentially useful medications are not made available to patients....

journal_title：Gastroenterology clinics of North America

authors： Fontana RJ,Watkins PB

更新日期：1995-12-01 00:00:00

abstract：:Primary prevention of colonic adenomas and cancer through dietary interventions or chemoprevention has great appeal. This article discusses primary prevention goals and promising nutritional or chemopreventive strategies. There is substantial observational evidence that diets high in total calories and fat and or low ...

journal_title：Gastroenterology clinics of North America

authors： Gatof D,Ahnen D

更新日期：2002-06-01 00:00:00

abstract：:Determining the perioperative risks associated with surgical procedures performed in patients with HIV disease is a difficult and complex task. Because HIV is a contagious, blood-borne pathogen, it threatens the health and well-being of both patient and health care provider. Despite poor early results, there is now co...

journal_title：Gastroenterology clinics of North America

authors： Harris HW,Schecter WP

更新日期：1997-06-01 00:00:00

abstract：:The cellular and molecular understanding of human gastroparesis has markedly improved due to studies on full-thickness gastric biopsies. A decrease in the number of interstitial cells of Cajal (ICC) and functional changes in ICC constitutes the hallmark cellular feature of gastroparesis. More recently, in animal model...

journal_title：Gastroenterology clinics of North America

authors： Chikkamenahalli LL,Pasricha PJ,Farrugia G,Grover M

更新日期：2020-09-01 00:00:00

abstract：:Constipation and diarrhea are common during pregnancy, occurring in up to one-third of women. Constipation is often the result of physiologic changes that occur during pregnancy, usually from hormonal effects on gastrointestinal motility. Diarrhea, on the other hand, is often caused by the same disorders responsible f...

journal_title：Gastroenterology clinics of North America

authors： Bonapace ES Jr,Fisher RS

更新日期：1998-03-01 00:00:00

abstract：:The effect of Helicobacter pylori eradication treatment needs confirmation in patients with persistent symptoms and in those with complicated peptic ulcer. Endoscopic surveillance after eradication is needed in patients with advanced premalignant gastric lesions, previous early gastric cancer, gastric MALT lymphoma, a...

journal_title：Gastroenterology clinics of North America

authors： Kuipers EJ

更新日期：2015-09-01 00:00:00

abstract：:Living donor intestinal transplantation (LDIT) has been improved leading to results comparable to those obtained with deceased donors. LDIT should be limited to specific indications and patient selection. The best indication is combined living donor intestinal/liver transplantation in pediatric recipients with intesti...

journal_title：Gastroenterology clinics of North America

authors： Tzvetanov IG,Tulla KA,D'Amico G,Benedetti E

更新日期：2018-06-01 00:00:00

abstract：:Foreign body ingestion is a common occurrence in children and in specific high-risk groups of adults such as those with underlying esophageal disease, prisoners, the mentally retarded, and those with psychiatric illnesses. Although most foreign bodies pass through the gastrointestinal tract without difficulty, sharp, ...

journal_title：Gastroenterology clinics of North America

authors： Brady PG

更新日期：1991-12-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) represents a global public health burden. NAFLD, while strongly associated with the metabolic syndrome, can occur independently from existing metabolic diseases. In addition to liver-related disease burden and mortality, significant extrahepatic disease outcomes coexist with NA...

journal_title：Gastroenterology clinics of North America

authors： Wattacheril J

更新日期：2020-03-01 00:00:00

abstract：:Treatment with a combination of radiation therapy and chemotherapy currently allows about 80 per cent of patients with epidermoid carcinomas of the anal canal to retain anorectal function, with about a 70 per cent likelihood of cure at 5 years. In these programs, radical surgery is reserved for the management of resid...

journal_title：Gastroenterology clinics of North America

authors： Cummings BJ

更新日期：1987-03-01 00:00:00

abstract：:Alpha 1-antitrypsin deficiency is the most common genetic cause of liver disease in infants and children and is the most common genetic disease for which liver transplantation is indicated. This article presents the clinical manifestations, diagnosis, treatment, and pathogenesis of alpha 1-antitrypsin deficiency. ...

journal_title：Gastroenterology clinics of North America

authors： Perlmutter DH

更新日期：1995-03-01 00:00:00

abstract：:The presence of stigmata of hemorrhage in a peptic ulcer indicate an increased risk of rebleeding and the need for endoscopic intervention. Clinical trials indicate that laser photocoagulation, multipolar and heater probe coagulation, and injection therapy are all effective in decreasing bleeding from peptic ulcer dis...

journal_title：Gastroenterology clinics of North America

authors： Zuccaro G Jr

更新日期：1993-12-01 00:00:00

abstract：:Women have started to enter gastroenterology (GI) in significant numbers over the past 5 years, although they are still underrepresented compared with the proportion of female graduating medical students. This underrepresentation is most likely caused by the culture of GI where female students and residents have felt ...

journal_title：Gastroenterology clinics of North America

authors： Elta GH

更新日期：2011-06-01 00:00:00

abstract：:Because functional bowel disorders have no reliable markers, they must be defined by their symptoms. The various constellations of symptoms (syndromes) may have different mechanisms, differential diagnoses, and treatments. Therefore, precise classification is important on clinical and scientific grounds. Functional bo...

journal_title：Gastroenterology clinics of North America

authors： Thompson WG

更新日期：1991-06-01 00:00:00

abstract：:A wide spectrum of gastrointestinal illnesses impairs bone health and can result in bone pain, demineralization, and fracture. This article summarizes current knowledge of the skeletal pathology exhibited in patients with diseases of the liver, biliary tree, pancreas, and bowel. Mechanisms responsible for these syndro...

journal_title：Gastroenterology clinics of North America

authors： Lipkin EW

更新日期：1998-06-01 00:00:00

abstract：:Precursor lesions in the GIT include flat dysplasias, adenomas, dysplasia superimposed on nonneoplastic polyps, endocrine cell dysplasia, ACF, and condyloma accuminatum. Interobserver variability can be a problem in reporting dysplasia, and ancillary techniques including flow cytometry, image analysis, proliferation m...

journal_title：Gastroenterology clinics of North America

authors： Haber MM

更新日期：2002-06-01 00:00:00

abstract：:Radiation therapy (RT) has been used to treat cancers for more than a century. Recent randomized trials have helped clarify the treatment recommendations in the use of RT for colorectal cancers. This article reviews these trials to illustrate key concepts, places these trials in perspective, and provides direction for...

journal_title：Gastroenterology clinics of North America

authors： Robertson JM

更新日期：2008-03-01 00:00:00

abstract：:Barrett's metaplasia develops in 6% to 14% of individuals with gastroesophageal reflux. Barrett's adenocarcinomas are increasing in epidemic proportions for, as yet unknown, reasons; approximately 0.5% to 1% of patients with Barrett's metaplasia develop adenocarcinoma. Heartburn duration and frequency (but not severit...

journal_title：Gastroenterology clinics of North America

authors： Reynolds JC,Waronker M,Pacquing MS,Yassin RR

更新日期：1999-12-01 00:00:00

abstract：:Patients with chest pain of presumed esophageal origin should be reassured and should undergo an esophageal manometry study. In patients with spastic esophageal disorders, a trial with calcium channel blockers or low-dose antidepressants used as visceral analgesics is the best approach. Inpatients with non GERD-relate...

journal_title：Gastroenterology clinics of North America

authors： Schmulson MJ,Valdovinos MA

更新日期：2004-03-01 00:00:00

abstract：:Pediatric patients with inflammatory bowel disease (IBD) stand to benefit from quality improvement (QI) due to the chronic nature of the disease, frequent interaction with the health care system, and exposure to high-risk treatments. The use of QI in health care has led to significant improvements in quality and relia...

journal_title：Gastroenterology clinics of North America

authors： Egberg MD,Kappelman MD,Gulati AS

更新日期：2018-12-01 00:00:00

abstract：:Upper gastrointestinal bleeding (UGIB) is the most common emergency condition in gastroenterology. Although peptic ulcer and esophagogastric varices are the predominant causes, other conditions account for up to 50% of UGIBs. These conditions, among others, include angiodysplasia, Dieulafoy and Mallory-Weiss lesions, ...

journal_title：Gastroenterology clinics of North America

authors： Tjwa ET,Holster IL,Kuipers EJ

更新日期：2014-12-01 00:00:00

abstract：:Surveillance for hepatocellular carcinoma (HCC) has become routine despite a lack of evidence of efficacy. Suitable candidates for surveillance include patients with cirrhosis and some subsets of noncirrhotic chronic hepatitis B carriers. The best surveillance testis ultrasonography at 6- to 12-month intervals. Serolo...

journal_title：Gastroenterology clinics of North America

authors： Sherman M,Takayama Y

更新日期：2004-09-01 00:00:00

abstract：:In the treatment of arthritis, NSAIDs are some of the most commonly used drugs, although the prescription of such drugs has been questioned due to their inherent risks for gastrointestinal compromise, platelet effects, and the potential for renal toxicity with long-term use. With the availability of celecoxib and rofe...

journal_title：Gastroenterology clinics of North America

authors： Simon LS

更新日期：2001-12-01 00:00:00

abstract：:This brief review summarizes the physiology and pharmacology of eicosanoids and describes how they have been tested for possible application in liver disease and transplantation. The objective is to trace the stepwise application from the laboratory to the bedside. Although many questions remain to be answered, the ob...

journal_title：Gastroenterology clinics of North America

authors： Ruwart MJ,Henley KS

更新日期：1996-06-01 00:00:00

abstract：:The view of surgical treatment of esophageal carcinoma is pessimistic. This is so because (1) most patients present late in the disease and are beyond the benefits of surgical therapy for cure, (2) resection is associated with a high operative mortality, and (3) the poor 5-year survival rates for surgical resection ci...

journal_title：Gastroenterology clinics of North America

authors： Bremner RM,DeMeester TR

更新日期：1991-12-01 00:00:00

abstract：:This article reviews current concepts regarding the pathobiology of cystic fibrosis pancreatic disease. It summarizes recent studies on the relationship between CFTR mutations and pancreatitis, and it reviews several unresolved issues in the field. ...

journal_title：Gastroenterology clinics of North America

authors： Cohn JA,Mitchell RM,Jowell PS

更新日期：2004-12-01 00:00:00

abstract：:Gastric cancers are a histologically heterogenous group of neoplasms arising from unique epidemiologic and molecular backgrounds. There is accumulating evidence that the intestinal type of gastric adenocarcinoma develops through a multistep process beginning with chronic gastritis triggered primarily by Helicobacter p...

journal_title：Gastroenterology clinics of North America

authors： Yakirevich E,Resnick MB

更新日期：2013-06-01 00:00:00

abstract：:Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids. New studies on alternative delivery systems and different corticosteroids (eg...

journal_title：Gastroenterology clinics of North America

authors： Contreras EM,Gupta SK

更新日期：2014-06-01 00:00:00

abstract：:Numerous extraintestinal diseases have been associated with IBD. The role of the gastrointestinal tract in host response to the foreign antigens present in the gut makes the enteric immune system highly susceptible to any external perturbation to the system. Dysregulation of the enteric immune response results in path...

journal_title：Gastroenterology clinics of North America

authors： Su CG,Judge TA,Lichtenstein GR

更新日期：2002-03-01 00:00:00