当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > The effects of differential gene expression on coding sequence features: analysis by one-way ANOVA.

The effects of differential gene expression on coding sequence features: analysis by one-way ANOVA.

Abstract：

:It is well-established that non-random patterns in coding DNA sequence (CDS) features can be partially explained by translational selection. Recent extensions of microarray and proteomic expression data have stimulated many genome-wide investigations of the relationships between gene expression and various CDS features. However, only modest correlations have been found. Here we introduced the one-way ANOVA, a more powerful extension of previous grouping methods, to re-examine these relationships at the whole genome scale for Saccharomyces cerevisiae, where genome-wide protein abundance has been recently quantified. Our results clarify that coding sequence features are inappropriate for use as genome-wide estimators for protein expression levels. This analysis also demonstrates that one-way ANOVA is a powerful and simple method to explore the influence of gene expression on CDS features.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Wu G,Nie L,Freeland SJ

doi

10.1016/j.bbrc.2007.05.043

subject

Has Abstract

pub_date

2007-07-13 00:00:00

pages

1108-13

issue

4

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(07)01014-5

journal_volume

358

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Distance between the basic group of the amino acid residue's side chain in position P1 of trypsin inhibitor CMTI-III and Asp189 in the substrate pocket of trypsin has an essential influence on the inhibitory activity.

    abstract：:Three new analogues of trypsin inhibitor CMTI-III were synthesized by the solid-phase method: [Lys5]-CMTI-III, [Orn5]CMTI-III and [Dab5]CMTI-III. Only one analogue with L-lysine residue in position P1 showed inhibitory activity of the same order of magnitude as did wild CMTI-III. Two remaining analogues were completel...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7752

    authors： Jaśkiewicz A,Lesner A,Rózycki J,Rodziewicz S,Rolka K,Ragnarsson U,Kupryszewski G

    更新日期：1997-11-26 00:00:00

  • Conjugal transfer of hydrogen-oxidizing ability of Alcaligenes hydrogenophilus to Pseudomonas oxalaticus.

    abstract：:Conjugal transfer of hydrogen-oxidizing ability (Hox) of the hydrogen bacterium Alcaligenes hydrogenophilus was examined. Intraspecific cross of plasmid pHG21-a that encodes hydrogenases that mediate hydrogen oxidation was most frequent at 25 C; the optimal temperature for growth was 30 C. The plasmid could be transfe...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)91182-4

    authors： Umeda F,Min H,Urushihara M,Okazaki M,Miura Y

    更新日期：1986-05-29 00:00:00

  • Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double-stranded DNA.

    abstract：:Zta is a bZIP transcription factor (TF) in the Epstein-Barr virus that binds unmethylated and methylated DNA sequences. Substitution of cysteine 189 of Zta to serine (Zta(C189S)) results in a virus that is unable to execute the lytic cycle, which was attributed to a change in binding to methylated DNA sequences. To le...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.05.080

    authors： Ray S,Tillo D,Assad N,Ufot A,Deppmann C,Durell SR,Porollo A,Vinson C

    更新日期：2018-07-02 00:00:00

  • Activation of farnesoid X receptor induces RECK expression in mouse liver.

    abstract：:Farnesoid X receptor (FXR) belongs to the ligand-activated nuclear receptor superfamily, and functions as a transcription factor regulating the transcription of numerous genes involved in bile acid homeostasis, lipoprotein and glucose metabolism. In the present study, we identified RECK, a membrane-anchored inhibitor ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.11.082

    authors： Peng X,Wu W,Zhu B,Sun Z,Ji L,Ruan Y,Zhou M,Zhou L,Gu J

    更新日期：2014-01-03 00:00:00

  • Tissue-specific expression of the prostatic acid phosphatase promoter constructs.

    abstract：:Human prostatic acid phosphatase (hPAP) is intensely expressed in epithelial cells of the prostate gland following puberty. Its regulatory regions were analyzed in transgenic mice and cell line transfections, in order to clarify the mechanisms of tissue-specific gene expression. A construct containing the sequence of ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.10.071

    authors： Shan J,Porvari K,Kivinen A,Patrikainen L,Halmekytö M,Jänne J,Vihko P

    更新日期：2003-11-28 00:00:00

  • Cloning and expression of human rotavirus spike protein, VP8*, in Escherichia coli.

    abstract：:A system for the expression and purification of soluble VP8*, part of the human rotavirus (HRV) spike protein, was established by expressing VP8* as a fusion protein with glutathione S-transferase (GST). VP8 cDNA, from the Wa strain of HRV, was prepared by RT-PCR, cloned into a pUC18 plasmid, and inserted into a pGEX-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.4717

    authors： Kovacs-Nolan J,Sasaki E,Yoo D,Mine Y

    更新日期：2001-04-20 00:00:00

  • Transgene integration into the human AAVS1 locus enhances myosin II-dependent contractile force by reducing expression of myosin binding subunit 85.

    abstract：:The adeno-associated virus site 1 (AAVS1) locus in the human genome is a strong candidate for gene therapy by insertion of an exogenous gene into the locus. The AAVS1 locus includes the coding region for myosin binding subunit 85 (MBS85). Although the function of MBS85 is not well understood, myosin II-dependent contr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.08.018

    authors： Mizutani T,Li R,Haga H,Kawabata K

    更新日期：2015-09-18 00:00:00

  • T cell receptor signalling results in rapid tyrosine phosphorylation of the linker protein LAT present in detergent-resistant membrane microdomains.

    abstract：:Stimulation of human T cell line Jurkat results in rapid tyrosine phosphorylation of a 35-38 kDa protein that is found in large and buoyant detergent-resistant membrane microdomains containing also glycosylphosphatidylinositol (GPI)-anchored proteins, glycolipids and Src-family protein tyrosine kinases ("GPI-microdoma...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.8857

    authors： Brdiĉka T,Cerný J,Horejŝí V

    更新日期：1998-07-20 00:00:00

  • Melanoregulin is stably targeted to the melanosome membrane by palmitoylation.

    abstract：:In mammals, pigments are made by melanocytes within a specialized organelle, the melanosome. Mature, pigment-laden melanosomes are then transferred to keratinocytes to drive the visible pigmentation of the animal's hair and skin. The dilute suppressor (dsu) locus encodes an extragenic suppressor of the pigmentation de...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.08.064

    authors： Wu XS,Martina JA,Hammer JA 3rd

    更新日期：2012-09-21 00:00:00

  • Cytokines and related receptor-mediated signaling pathways.

    abstract：:Cytokines represent a multi-diverse family of polypeptide regulators; they are of relatively low molecular weight, pharmacologically active proteins that are secreted by one cell for the purpose of altering either its own functions (autocrine effect) or those of adjacent cells (paracrine effect). Cytokines are small, ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/s0006-291x(02)02287-8

    authors： Haddad JJ

    更新日期：2002-10-04 00:00:00

  • Affinity of 22-oxa-1,25(OH)2D3 for 1,25-dihydroxyvitamin D receptor and its effects on the synthesis of osteocalcin in human osteosarcoma cells.

    abstract：:A new 1,25-dihydroxyvitamin D3 analog, 22-oxa-1,25(OH)2D3, which may have pharmaceutical use, e.g., in the treatment of psoriasis, was studied using cultured MG-63 human osteosarcoma cells. We found that the new compound binds to 1,25-dihydroxyvitamin D receptors and regulates receptor mRNA levels like the natural lig...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)90377-y

    authors： Valaja T,Mahonen A,Pirskanen A,Mäenpää PH

    更新日期：1990-06-15 00:00:00

  • Covalent cross-linking of insulin-like growth factor-1 to a specific inhibitor from human serum.

    abstract：:Previous studies have shown that a specific inhibitor of insulin-like growth factor (IGF) action in vitro can be isolated from normal human serum and subsequently partially purified on an IGF-affinity column. The ability of the inhibitor to bind the IGFs has now been confirmed directly using covalent cross-linking tec...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)91225-8

    authors： Ooi GT,Herington AC

    更新日期：1986-05-29 00:00:00

  • Gastric and thymic assay of acute oral treatment of rats with nitric oxide esters of ibuprofen or indomethacin.

    abstract：:Two common non-steroidal anti-inflammatory drugs (NSAIDs) and their nitric oxide (NO) adducts were evaluated for effects on stomach and thymus. Following 4-h duration (acute) oral dosing of fasted male Wistar rats, 1.33 x 10(-4)mol/kg of ibuprofen caused significant visual irritation score and microscopic thinning, al...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.06.149

    authors： Downing JE,Madden JC,Ingram MJ,Rostron C

    更新日期：2005-08-26 00:00:00

  • Relative positioning of the T cell and B cell determinants on an immunogenic peptide: its influence on antibody response.

    abstract：:A tryptic peptide of bovine beta-casein (amino acid residues 184-202) was used as a model antigen to investigate how the relative position of the (helper) T cell and B cell determinants on a protein antigen influences the antibody response. Immunization with the peptide elicited a considerably higher anti-peptide resp...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)90402-9

    authors： Hachimura S,Enomoto A,Kaminogawa S

    更新日期：1990-06-15 00:00:00

  • Expression of enhancer binding factors associated with various cell types of lung cancer.

    abstract：:Differential expression of nuclear factors binding specifically to AP-1, AP-2, AP-3, and NF-I/CTF enhancer elements was found in the various cell types of human lung carcinoma cells. Adenocarcinoma and squamous carcinoma cells seemed to express higher levels of these factors than large-cell carcinoma and small-cell ca...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)81174-x

    authors： Wong YC,Bernal SD

    更新日期：1991-10-31 00:00:00

  • A peptide mimetic of an anti-CD4 monoclonal antibody by rational design.

    abstract：:The development of rational methods to design 'continuous' sequence mimetics of discontinuous regions of protein sequence has, to now, been only marginally successful. This has been largely due to the difficulty of constraining the recognition elements of a mimetic structure to the relative conformational and spatial ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)01131-8

    authors： Casset F,Roux F,Mouchet P,Bes C,Chardes T,Granier C,Mani JC,Pugnière M,Laune D,Pau B,Kaczorek M,Lahana R,Rees A

    更新日期：2003-07-18 00:00:00

  • Intracellular [Ca2+] and K+ and Cl- efflux responses in submandibular cells of neonatal and adult rats.

    abstract：:The effects of graded doses (5 x 10(-8) to 10(-5)) acetylcholine on intracellular Ca2+ and on 86Rb and 36Cl efflux were compared in submandibular cell clusters of 1 and 7 day-old and adult rats. Initial Ca2+ peaks were similar at agonists concentrations lower than 10(-7) M but the release of Rb+ and Cl- were smaller i...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)91353-r

    authors： Seagrave JC,Ramsey RC,Barker S,Martinez JR

    更新日期：1992-11-16 00:00:00

  • The operation of Na+/Ca2+ exchanger prevents intracellular Ca2+ overload and hepatocyte killing following iron-induced lipid peroxidation.

    abstract：:Stimulation of lipid peroxidation by incubating isolated rat hepatocytes with ADP/FeCl3 caused a time dependent increase in cytosolic free Ca2+ levels, without influencing cellular Na+ content. Omission of Na+ from the incubation medium greatly increased the accumulation of Ca2+, which was partially reverted upon tran...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1409

    authors： Carini R,Bellomo G,Dianzani MU,Albano E

    更新日期：1995-03-17 00:00:00

  • Protein kinase C phosphorylates and activates GTP cyclohydrolase I in rat renal mesangial cells.

    abstract：:GTP cyclohydrolase I is the rate-limiting enzyme in the de novo synthesis pathway of tetrahydrobiopterin which is an essential cofactor for all NO synthase isoforms. The expression of GTP cyclohydrolase I is regulated on a transcriptional level by a variety of cytokines like interleukin 1beta or tumor necrosis factor ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.9552

    authors： Lapize C,Plüss C,Werner ER,Huwiler A,Pfeilschifter J

    更新日期：1998-10-29 00:00:00

  • Increased immunoreactive neuropeptide Y in platelets of spontaneously hypertensive rats (SHR).

    abstract：:A high concentration of immunoreactive neuropeptide Y was observed in rat platelets using a specific and sensitive radioimmunoassay for neuropeptide Y. Three kinds of high performance liquid chromatography combined with radioimmunoassay for neuropeptide Y showed that immunoreactive neuropeptide Y in rat platelets is i...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)92759-9

    authors： Ogawa T,Kitamura K,Kawamoto M,Eto T,Tanaka K

    更新日期：1989-12-29 00:00:00

  • Bitter taste receptor T2R1 activities were compatible with behavioral sensitivity to bitterness in chickens.

    abstract：:Clarification of the mechanism of the sense of taste in chickens will provide information useful for creating and improving new feedstuffs for chickens, because the character of the taste receptors in oral tissues affects feeding behavior in animals. In this study, we focused on the sensitivity to bitterness in chicke...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.03.056

    authors： Hirose N,Kawabata Y,Kawabata F,Nishimura S,Tabata S

    更新日期：2015-05-01 00:00:00

  • Aralin, a type II ribosome-inactivating protein from Aralia elata, exhibits selective anticancer activity through the processed form of a 110-kDa high-density lipoprotein-binding protein: a promising anticancer drug.

    abstract：:Aralin from Aralia elata is a newly identified type II ribosome- inactivating protein, which preferentially induces apoptosis in cancer cells. In this study, we identified that the aralin receptor is a 110-kDa high-density lipoprotein-binding protein (HDLBP), which functions as a HDL receptor. The sensitivities of tum...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.09.067

    authors： Otsuka H,Gotoh Y,Komeno T,Ono T,Kawasaki Y,Iida N,Shibagaki Y,Hattori S,Tomatsu M,Akiyama H,Tashiro F

    更新日期：2014-10-10 00:00:00

  • Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells.

    abstract：:Licochalcone (LA) is a novel estrogenic flavonoid isolated from PC-SPES composition herb licorice root that was reported to show significant antitumor activity in various malignant human cell lines. To better understand its anti-CaP activities, we have investigated LA-elicited growth control and induction of apoptosis...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.07.094

    authors： Fu Y,Hsieh TC,Guo J,Kunicki J,Lee MY,Darzynkiewicz Z,Wu JM

    更新日期：2004-09-10 00:00:00

  • The zinc-finger transcription factor BcMF20 and its orthologs in Cruciferae which are required for pollen development.

    abstract：:Brassica campestris Male Fertility 20 (BcMF20) is a typical zinc-finger transcription factor that was previously isolated from flower buds of Chinese cabbage (Brassica campestris ssp. chinensis). By applying expression pattern analysis, it can be known that BcMF20 was specifically and strongly expressed in tapetum and...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.06.108

    authors： Han YY,Zhou HY,Xu LA,Liu XY,Fan SX,Cao JS

    更新日期：2018-09-05 00:00:00

  • Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression.

    abstract：:We previously reported that the suppression of SIRT2, an NAD + -dependent protein deacetylases, induces p53 accumulation via degradation of p300 and the subsequent MDM2 degradation, eventually leading to apoptosis in HeLa cells. The present study identified a novel pathway of p53 accumulation by SIRT2 suppression in H...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.11.136

    authors： Li Y,Kokura K,Inoue T

    更新日期：2019-01-01 00:00:00

  • TAZ is downregulated by dexamethasone during the differentiation of 3T3-L1 preadipocytes.

    abstract：:TAZ (transcriptional co-activator with PDZ binding motif) is a transcriptional modulator of mesenchymal stem cell differentiation. We have found that TAZ was expressed in postconfluent 3T3-L1 preadipocytes and downregulated during differentiation. Downregulation of TAZ was specifically mediated by dexamethasone (DEX),...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.02.074

    authors： He Q,Huang HY,Zhang YY,Li X,Qian SW,Tang QQ

    更新日期：2012-03-16 00:00:00

  • The role of MAP4K3 in lifespan regulation of Caenorhabditis elegans.

    abstract：:The TOR pathway is a kinase signaling pathway that regulates cellular growth and proliferation in response to nutrients and growth factors. TOR signaling is also important in lifespan regulation - when this pathway is inhibited, either naturally, by genetic mutation, or by pharmacological means, lifespan is extended. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.07.113

    authors： Khan MH,Hart MJ,Rea SL

    更新日期：2012-08-24 00:00:00

  • Catabolism of intact type VI collagen microfibrils: susceptibility to degradation by serine proteinases.

    abstract：:We present the first direct biochemical evidence for the turnover of intact type VI collagen microfibrils. Matrix-degrading enzymes of the serine proteinase class, including rat mast cell chymases I and II, human mast cell tryptase, neutrophil elastase, cathepsin G and trypsin, were able to catabolize intact type VI c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1349

    authors： Kielty CM,Lees M,Shuttleworth CA,Woolley D

    更新日期：1993-03-31 00:00:00

  • MNT inhibits the migration of human hepatocellular carcinoma SMMC7721 cells.

    abstract：:Max binding protein (MNT) is a member of the Myc/Max/Mad network that plays a role in cell proliferation, differentiation and apoptosis. We previously observed that MNT was differentially expressed in hepatocellular carcinoma (HCC) and interacted with Nck1 by 2-DE. Nck family adaptor proteins function to couple tyrosi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.12.140

    authors： Wu J,Zhou Q,Wang Y,Zhou X,Li J

    更新日期：2012-02-03 00:00:00

  • Functional characterization of Brassica napus DNA topoisomerase Iα-1 and its effect on flowering time when expressed in Arabidopsis thaliana.

    abstract：:Previous studies have shown that DNA topoisomerase Iα (AtTOP1α) has specific developmental functions during growth and development in Arabidopsis thaliana. However, little is known about the roles of DNA topoisomerases in the closely related and commercially important plant, rapeseed (Brassica napus). Here, the full-l...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.03.011

    authors： Gao C,Qi S,Liu K,Li D,Jin C,Duan S,Zhang M,Chen M

    更新日期：2017-04-22 00:00:00