Sulindac loaded alginate beads for a mucoprotective and controlled drug release.

abstract：:Biodegradable polymers for localized delivery of antibiotics have emerged as an important approach to treating orthopaedic infections. In chronic forms of osteomyelitis which are thought to be associated with bacterial biofilm, localized delivery of a suitable antibiotic is desirable. This paper describes the formulat...

journal_title：Journal of microencapsulation

authors： Habib M,Onyilofor S,Ebube NK,Owusu-Ababio G

更新日期：1999-01-01 00:00:00

abstract：:The purpose of present research work was to develop mucoadhesive microspheres for nasal delivery with the aim to avoid hepatic first-pass metabolism, improve therapeutic efficacy and enhance residence time. For the treatment of migraine, hydroxypropyl methylcellulose (HPMC) K4M and K15M based microspheres containing s...

journal_title：Journal of microencapsulation

authors： Jain SA,Chauk DS,Mahajan HS,Tekade AR,Gattani SG

更新日期：2009-12-01 00:00:00

abstract：:The objective of this work was to prepare and evaluate ketoprofen-loaded albumin microspheres for intramuscular administration. Microspheres were prepared by emulsion cross-linking method using a 2(3) factorial design and the effect of different factors on entrapment efficiency was determined. Microspheres were evalua...

journal_title：Journal of microencapsulation

authors： Mathew ST,Devi SG,Prasanth VV,Vinod B

更新日期：2009-08-01 00:00:00

abstract：:Alginate bead containing calcium carbonate particle were prepared by dropping the suspension of alginate/calcium carbonate (4/1, w/w) into aqueous solution of CaCl(2) (0.1 M). The pH-dependent release property of the bead was observed for 12 h using blue dextran as a model drug. The release increased up to 4 h in a sa...

journal_title：Journal of microencapsulation

authors： Han MR,Kwon MC,Lee HY,Kim JC,Kim JD,Yoo SK,Sin IS,Kim SM

更新日期：2007-12-01 00:00:00

abstract：:Multilamellar liposomes incorporating essential oil of Brazilian cherry (Eugenia uniflora L.) leaves were produced by dry film hydration. Gas chromatography demonstrated the compounds found in the essential oil were effectively incorporated in the aqueous dispersions of liposomes. Differential scanning calorimetry ana...

journal_title：Journal of microencapsulation

authors： Yoshida PA,Yokota D,Foglio MA,Rodrigues RA,Pinho SC

更新日期：2010-01-01 00:00:00

abstract：:Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form. ...

journal_title：Journal of microencapsulation

authors： Vidmar V,Pepeljnjak S,Jalsenjak I

更新日期：1985-10-01 00:00:00

abstract：AIM:To study the effect of poly(d,l-lactic-co-glycolic acid) (PLGA) microparticles (MPs) preparation techniques on particle physical characterization with special emphasis on burst drug release. METHODS:A basic drug clozapine was used in combination with acid-terminated PLGA. Two approaches for MP preparation were com...

journal_title：Journal of microencapsulation

authors： Ishak RA,Mortada ND,Zaki NM,El-Shamy Ael-H,Awad GA

更新日期：2014-01-01 00:00:00

abstract：:The preparation of dipyridamole (DIP) alginate (alg) microspheres by different methods or the incorporation of tragacanth (trgh), pectin or Eudragit L-100 55 (Eud) in alg microsphere formulations did not provide a prolonged release of DIP at pH 1.2. Tabletted microsphere formulations containing alg, trgh, pectin, sodi...

journal_title：Journal of microencapsulation

authors： Gürsoy A,Karakuş D,Okar I

更新日期：1999-07-01 00:00:00

abstract：:Monodisperse Ca-alginate microspheres were prepared using the membrane emulsification method. Three ionic types of drugs (anionic, cationic and non-ionic) were incorporated into the microspheres, and the effects of sodium alginate concentration and the pressure applied during the dispersing process on the properties o...

journal_title：Journal of microencapsulation

authors： You JO,Park SB,Park HY,Haam S,Chung CH,Kim WS

更新日期：2001-07-01 00:00:00

abstract：:Drug-free polylactic acid (PLA) microspheres were prepared by an emulsification-solvent evaporation technique using different types of protective colloids. The influence of five types of hydrophilic prolymers (polysaccharides, proteins, synthetic cellulose derivatives, synthetic nonionic polymers and surfactants) on t...

journal_title：Journal of microencapsulation

authors： Lin SY,Chen KS,Teng HH

更新日期：1998-05-01 00:00:00

abstract：AIM:This study aimed to evaluate the protective effect of flaxseed mucilage on the co-extrusion microencapsulation of Lactobacillus rhamnosus GG. METHODS:Core flow rate, chitosan coating, and flaxseed mucilage concentration were optimised for the microencapsulation of L. rhamnosus. The microbeads were characterised an...

journal_title：Journal of microencapsulation

authors： Lai K,How Y,Pui L

更新日期：2020-12-28 00:00:00

abstract：:A novel method for preparing the PLGA nanospheres with hydrophilic surface has been designed and characterized. Because of good solubility of tetraglycol in water, PLGA (poly(lactide-co-glycolide)) nanospheres were formed by spraying the PLGA/tetraglycol solution into water. The size of PLGA nanospheres was manipulate...

journal_title：Journal of microencapsulation

authors： Kim BK,Kim D,Cho SH,Yuk SH

更新日期：2004-11-01 00:00:00

abstract：:Co-flowing media of a polymeric solution (30 wt% polymethylsilsesquioxane in ethanol) and a ceramic suspension (10 wt% alumina in glycerol) were subjected to an electric field. The flow rates of the media (10-30 microL min(-1)) and the applied voltage (0-11 kV) were varied systematically during the experimentation by ...

journal_title：Journal of microencapsulation

authors： Nangrejo M,Ahmad Z,Edirisinghe M

更新日期：2010-01-01 00:00:00

abstract：:To improve poor water solubility of cyclosporine A (CsA), hydroxypropyl-beta-cyclodextrin (HPβCD) was incorporated into the nanoparticle formulation. Solid complexes of CsA with HPβCD in different ratios were prepared by the kneading method. CsA containing alone or in combination with HPβCD in poly-lactide-co-glycolid...

journal_title：Journal of microencapsulation

authors： Aksungur P,Demirbilek M,Denkbaş EB,Unlü N

更新日期：2012-01-01 00:00:00

abstract：AIMS:This study was aimed to develop Isotretinoin (ITN) and α-tocopherol acetate (α-TA) loaded solid lipid nanoparticle topical gel for better skin sensitivity and potentiation of efficacy. METHODS:ITN and α-TA-loaded solid lipid nanoparticles (AE-SLN) were prepared by microemulsion method with glyceryl mono-stearate ...

journal_title：Journal of microencapsulation

authors： Gupta S,Wairkar S,Bhatt LK

更新日期：2020-12-01 00:00:00

abstract：:Moisture curing type self-healing microcapsules become more attractive, while instability of active core material crippled the efficiency of self-healing behaviour. Polyurea (PU)/melamine formaldehyde (MF) double-layered self-healing microcapsules containing isophorone diisocyanate (IPDI) core with high and stable cor...

journal_title：Journal of microencapsulation

authors： Ming Y,Hu J,Xing J,Wu M,Qu J

更新日期：2016-06-01 00:00:00

abstract：:Abietic acid was isolated from rosin N Grade (ISI) by a simple process and the product was further standardized. Sulphadiazine microcapsules were prepared by the solvent evaporation technique, using abietic acid as a wall-forming material. Discrete, spherical and free-flowing microcapsules were obtained by phase separ...

journal_title：Journal of microencapsulation

authors： Puranik PK,Manekar NC,Dorle AK

更新日期：1992-10-01 00:00:00

abstract：:The influence of drug particle size on the production of enteric beads by a polymer precipitation technique was investigated. Drug particle dimensions are known to play an important role in most microencapsulation techniques. Bead morphology was greatly influenced by drug particle size, and spherical shaped beads coul...

journal_title：Journal of microencapsulation

authors： Cerdeira AM,Gouveia LF,Goucha P,Almeida AJ

更新日期：2000-11-01 00:00:00

abstract：:Objective: To improve the water solubility and enhance the oral bioavailability of gambogenic acid (GNA). Methods: GNA-phospholipid complex (GNA-PLC) micelles were successfully prepared by anti-solvent method. Results: The encapsulation efficiency of GNA-PLC micelles can reach 99.33 % (w/w). The average particle size ...

journal_title：Journal of microencapsulation

authors： Wang B,Cheng W,Zhang C,Bao Y,Zha L,Qian J,Hong L,Chen W

更新日期：2019-09-01 00:00:00

abstract：:In this study, the anticancer activities of two siRNA carriers were compared using a human lung adenocarcinoma epithelial cell line (A549). Firstly, poly(styrene)-graft-poly(linoleic acid) (PS-g-PLina) and poly(styrene)-graft-poly(linoleic acid)-graft-poly(ethylene glycol) (PS-g-PLina-g-PEG) graft copolymers were synt...

journal_title：Journal of microencapsulation

authors： Anilmis NM,Kara G,Kilicay E,Hazer B,Denkbas EB

更新日期：2019-11-01 00:00:00

abstract：:Atomic force microscopy (AFM) is recognized a suitable and powerful technique for surface and morphological analysis. Even if until now this technique has not been frequently used in the pharmaceutical field, it can contribute to an accurate morphologic characterization of microspheres and nanospheres. In this work, a...

journal_title：Journal of microencapsulation

authors： Dorati R,Patrini M,Perugini P,Pavanetto F,Stella A,Modena T,Genta I,Conti B

更新日期：2006-03-01 00:00:00

abstract：:Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...

journal_title：Journal of microencapsulation

authors： Levy MC,Andry MC

更新日期：1991-07-01 00:00:00

abstract：:Microencapsulation of ketoprofen using Eudragit RS and RL (acrylic resins) was investigated based on the dispersion system of ketoprofen-containing acetone in liquid paraffin. Aluminium tristearate was used as an additive for the preparation of microcapsules. Good reproducibility was observed in the microencapsulation...

journal_title：Journal of microencapsulation

authors： Goto S,Kawata M,Nakamura M,Maekawa K,Aoyama T

更新日期：1986-10-01 00:00:00

abstract：:Chitosan microspheres were prepared by an emulsion-phase separation technique without the use of chemical cross-linking agents; alternatively, ionotropic gelation was employed in a w/o emulsion. The possibility of three kinds of anions (tripolyphosphate, citrate and sulphate) to interact with chitosan was investigated...

journal_title：Journal of microencapsulation

authors： Shu XZ,Zhu KJ

更新日期：2001-03-01 00:00:00

abstract：:Liposomes containing Isovist were prepared by controlled detergent dialysis as well as by reverse phase evaporation. After preparation these liposomes were lyophilized and then submitted to sterilization by ethylene oxide. Prior to lyophilization, trehalose was added as a protective agent to preserve the size of the l...

journal_title：Journal of microencapsulation

authors： Ratz H,Freise J,Magerstedt P,Schaper A,Preugschat W,Keyser D

更新日期：1989-10-01 00:00:00

abstract：:Chlorogenic acid (CA) is a natural compound used as an antioxidant in the preparation of food, drugs, and cosmetics. Due to their low stability and bioavailability, many researchers have studied the encapsulation of CA in various delivery colloidal systems. The aim of this study was to evaluate the stability of water-...

journal_title：Journal of microencapsulation

authors： Dima C,Dima S

更新日期：2018-09-01 00:00:00

abstract：:The body distribution of surfactant-coated and non-coated poly(methyl methacrylate) nanoparticles with a size of 131 +/- 30 nm after intravenous injection into rats was investigated. The coating materials were poloxamine 904, poloxamine 908, poloxamine 1508, poloxamer 338, and Brij 35. These materials were preselected...

journal_title：Journal of microencapsulation

authors： Tröster SD,Kreuter J

更新日期：1992-01-01 00:00:00

abstract：:Artificial chylomicron remnants were investigated as a new drug carrier system for the targeting of hepatic parenchymal cells. The emulsions presented here are similar in particle size and composition to natural lipoproteins. The preparations contained triolein, phospholipid, cholesterol and cholesteryl oleate. Egg yo...

journal_title：Journal of microencapsulation

authors： Vuaridel-Bonanomi ES,Weder HG

更新日期：1991-04-01 00:00:00

abstract：:Emulsions of menhaden oil and sodium caseinate (NaCas) incorporating carbohydrates of varying dextrose equivalence (DE) were spray-dried to yield encapsulated fish oil powders. The effects of carbohydrate DE (5.5-38), core/wall ratio and NaCas/carbohydrate ratio on microencapsulation efficiency (ME) and oxidative stab...

journal_title：Journal of microencapsulation

authors： Hogan SA,O'Riordan ED,O'Sullivan M

更新日期：2003-09-01 00:00:00

abstract：:Polyurethane modified with polylactic acid microcapsules were fabricated for controlled release of chlorpyrifos (one of the high usage solid phosphorous insecticides) via interfacial polymerisation with diphenylmethane diisocyanate, polyether triol, 1,4-butanediol and polylactic acid as modifier. The structure, morpho...

journal_title：Journal of microencapsulation

authors： Zheng T,Chen K,Chen W,Wu B,Sheng Y,Xiao Y

更新日期：2019-01-01 00:00:00