Abstract：
:The pathogenic potential of Propionibacterium acnes in implant-associated spine infections is increasingly recognized. However, the clinical findings and outcomes associated with this pathogen in nonimplant-associated spine infections are unknown. We retrospectively reviewed nine male patients who met our strict case definition for P. acnes vertebral osteomyelitis to determine whether the laboratory, radiographic, and histopathology found in these infections differs from that typically associated with vertebral osteomyelitis. We also determined clinical outcomes as they related to medical and surgical treatments rendered. Radiographic results, laboratory results, and histopathology results of patients with P. acnes vertebral osteomyelitis were often not those classically described for this disease. Two of the nine patients' imaging examinations did not suggest infection. Five of six patients had normal erythrocyte sedimentation rates at diagnosis. Three of six patients' histopathology did not show evidence of infection. Two patients whose treatment included spinal surgery with implant placement developed relapse of their infection. The remaining seven patients had rapid improvement with antimicrobial therapy. Patients with P. acnes vertebral osteomyelitis may present with atypical findings. Clinicians should be aware of the pathogenic potential of this organism, particularly following invasive spine procedures.
journal_name
Clin Orthop Relat Resjournal_title
Clinical orthopaedics and related researchauthors
Kowalski TJ,Berbari EF,Huddleston PM,Steckelberg JM,Osmon DRdoi
10.1097/BLO.0b013e318073c25dsubject
Has Abstractpub_date
2007-08-01 00:00:00pages
25-30eissn
0009-921Xissn
1528-1132journal_volume
461pub_type
杂志文章abstract：:Whether a preoperative long leg radiograph taken with the patient standing helps the surgeon reproduce a normal mechanical axis after total knee arthroplasty is unknown. The purpose of the current study was to evaluate whether a preoperative long leg radiograph helps to restore normal limb alignment after total knee a...
journal_title：Clinical orthopaedics and related research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00003086-200211000-00032
更新日期：2002-11-01 00:00:00
abstract：:Degradation of yttria-stabilized zirconia femoral heads in vivo has been linked to increased roughening and even fracture of the femoral head. To determine whether magnesia-stabilized zirconia is better suited to resist degradation, we characterized the monoclinic phase concentration, surface topography, and microhard...
journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：10.1097/BLO.0b013e318158b4d3
更新日期：2007-12-01 00:00:00
abstract：:Epidemiologic studies in Britain have shown that the incidence of Perthes' disease is higher in children from families of low socioeconomic status. The disease is associated with urban areas. The highest annual incidence recorded to date is 15.6 per 100,000 children younger than 15 years of age, in Liverpool, England....
journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：:In accepting this invitation to write a prefatory chapter as a mini professional autobiography, it has become all too obvious that this has touched a few nerve endings that had healed many years ago. Contemplating personal experiences, thoughts, and philosophies and then writing them should have a purpose. During thes...
journal_title：Clinical orthopaedics and related research
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:Reasons for reoperation after knee revision surgery are implant loosening, sepsis, extensor mechanism problems, fractures of bone or prosthetic components, wear debris, and limited range of motion. The purpose of this study was to review the complications requiring reoperation in a large number of condylar revision to...
journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
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更新日期：1993-01-01 00:00:00
abstract：:To investigate if an intensive rehabilitation program has a positive influence on the late course of an old, isolated anterior cruciate ligament rupture, patients were evaluated at an average of 8 years after injury. Seventy-five percent had acquired the injury during sporting activities. After diagnostic arthroscopy,...
journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：10.1097/00003086-199607000-00025
更新日期：1996-07-01 00:00:00
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journal_title：Clinical orthopaedics and related research
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更新日期：2011-12-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：10.1097/01.blo.0000150464.29883.ca
更新日期：2005-05-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
doi：
更新日期：1990-12-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
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更新日期：1979-07-01 00:00:00
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journal_title：Clinical orthopaedics and related research
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journal_title：Clinical orthopaedics and related research
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doi：
更新日期：1980-11-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
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更新日期：2003-11-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：
更新日期：1976-05-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
doi：10.1097/00003086-200010001-00006
更新日期：2000-10-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
doi：10.1007/s11999-014-3674-y
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：10.1097/00003086-200003000-00023
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journal_title：Clinical orthopaedics and related research
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journal_title：Clinical orthopaedics and related research
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doi：
更新日期：1990-05-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
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更新日期：2009-11-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
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更新日期：2005-02-01 00:00:00
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journal_title：Clinical orthopaedics and related research
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doi：10.1007/s11999-015-4553-x
更新日期：2016-04-01 00:00:00
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journal_title：Clinical orthopaedics and related research
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doi：
更新日期：1993-03-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:Nonunion of allograft-host junction after bone transplantation is not uncommon, and its treatment frequently is problematic. To improve the understanding of these nonunions, a retrospective review was performed of 163 nonunions in 945 patients who underwent allograft transplantation (17.3%) for various benign and mali...
journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章
doi：10.1097/00003086-200101000-00014
更新日期：2001-01-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
doi：
更新日期：1985-06-01 00:00:00
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journal_title：Clinical orthopaedics and related research
pub_type： 杂志文章,评审
doi：
更新日期：1988-01-01 00:00:00
