Abstract:
OBJECTIVE:The purpose of this study was to evaluate the associations of BMI versus metabolic syndrome with cardiovascular diseases (CVDs) in elderly Chinese individuals. RESEARCH DESIGN AND METHODS:We conducted a population-based cross-sectional study in an urban sample of 2,334 elderly subjects (943 men and 1,391 women). Subjects were classified by BMI (< or = 18.5, < 24, < 28, and > or = 28 kg/m2) and the presence or absence of metabolic syndrome, which was defined by International Diabetes Federation (IDF) criteria. CVDs included clinically diagnosed coronary heart disease (CHD), stroke, and peripheral arterial disease (PAD). RESULTS:The prevalence rates of overweight (BMI > or = 25 kg/m2) and metabolic syndrome according to the IDF criteria were 56.3% (53.9% in men and 57.9% in women) and 46.3% (34.8% in men and 54.1% in women), respectively. Increasing BMI was strongly associated with a higher risk of CHD, stroke, and PAD even after adjustments for metabolic syndrome and other CVD risk factors. Stratified analysis of participants with or without metabolic syndrome showed that BMI was independently associated with CHD, stroke, and PAD. CONCLUSIONS:Both overweight and metabolic syndrome are highly prevalent in this elderly Chinese population. BMI, as a measure of overall adiposity, is strongly associated with increased prevalence of CVD independent of metabolic syndrome.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
He Y,Jiang B,Wang J,Feng K,Chang Q,Zhu S,Fan L,Li X,Hu FBdoi
10.2337/dc06-2402subject
Has Abstractpub_date
2007-08-01 00:00:00pages
2128-34issue
8eissn
0149-5992issn
1935-5548pii
dc06-2402journal_volume
30pub_type
杂志文章,多中心研究相关文献
DIABETES CARE文献大全abstract:OBJECTIVE:The sympathetic nervous system and thiazolidinediones control lipid metabolism and have been implicated in body weight regulation. This study was conducted to determine whether the simultaneous activation of these two signaling systems might synergize to exert beneficial effects on the expression of key genes...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc06-1962
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:To project the number of people with diagnosed diabetes in the U.S. through 2050, accounting for changing demography and diabetes prevalence rates. RESEARCH DESIGN AND METHODS:We combined age-, sex-, and race-specific diagnosed diabetes prevalence rates-predicted from 1980-1998 trends in prevalence data from...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.24.11.1936
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:To analyze the relationship between maternal adiponectin (mAdiponectin) and cord blood adiponectin (cbAdiponectin) multimeric forms (high molecular weight [HMW], medium molecular weight [MMW], and low molecular weight [LMW]) in a cohort of gestational diabetes mellitus (GDM) and normal glucose-tolerant (NGT) ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-0788
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To understand the interrelationship of coronary artery disease (CAD) risk factors including hyperlipidemia, hypertension, and glucose intolerance to prevent and better manage this disease. RESEARCH DESIGN AND METHODS:We performed a 100-g oral glucose tolerance test in 2,113 subjects, and we evaluated their p...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.17.2.107
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. RESEARCH DESIGN AND METHODS:Men from the Health Professionals Follow-Up Study, who were i...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-2352
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:We have previously shown that 300 kcal from glucose intake induces a significant increase in reactive oxygen species (ROS) generation and nuclear factor-kappaB (NF-kappaB) binding in the circulating mononuclear cells in healthy normal subjects. We hypothesized that the intake of 300 calories as orange juice o...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-1458
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:Gestational diabetes mellitus (GDM) may cause obesity in the offspring. The objective was to assess the effect of treatment for mild GDM on the BMI of 4- to 5-year-old children. RESEARCH DESIGN AND METHODS:Participants were 199 mothers who participated in a randomized controlled trial of the treatment of mil...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc09-1810
更新日期:2010-05-01 00:00:00
abstract::This study shows the influence on plasma glucose concentrations of 45 min of mild exercise (48 +/- 4% of maximum aerobic capacity) performed 180 min after breakfast and 195 min after a subcutaneous injection of regular insulin by six type I (insulin-dependent) diabetic patients on a three-daily insulin injection regim...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.11.2.107
更新日期:1988-02-01 00:00:00
abstract:OBJECTIVE:To investigate the association of metabolic and lifestyle factors with possible diabetic polyneuropathy (DPN) and neuropathic pain in patients with early type 2 diabetes. RESEARCH DESIGN AND METHODS:We thoroughly characterized 6,726 patients with recently diagnosed diabetes. After a median of 2.8 years, we s...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-2277
更新日期:2020-06-01 00:00:00
abstract::In June 2012, 13 thought leaders convened in a Diabetes Care Editors' Expert Forum to discuss the concept of personalized medicine in the wake of a recently published American Diabetes Association/European Association for the Study of Diabetes position statement calling for a patient-centered approach to hyperglycemia...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc13-0512
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of systemic hyperbaric oxygen therapy (s HBOT) in addition to a comprehensive protocol in decreasing major amputation rate in diabetic patients hospitalized for severe foot ulcer. RESEARCH DESIGN AND METHODS:From August 1993 to August 1995, 70 diabetic subjects were consecutivel...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.19.12.1338
更新日期:1996-12-01 00:00:00
abstract::There was a need to design a questionnaire that could accurately assess the activity patterns of Native Americans to evaluate the relationship between physical activity and diabetes. Such a questionnaire was developed and implemented into the data collection scheme of the prospective Pima Indian Study of Arizona. The ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.13.4.401
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVE:The provariant of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor (PPAR)gamma has been identified as a risk allele for type 2 diabetes. The purpose of the present study was to reveal a significant association with pre-diabetic phenotypes in nondiabetic individuals based on a systematic...
journal_title:Diabetes care
pub_type: 杂志文章,meta分析
doi:10.2337/dc06-0513
更新日期:2006-11-01 00:00:00
abstract::The role of hyperinsulinemia in the pathogenesis of triglyceride (TG) and VLDL over-production in insulin-resistant states remains controversial. While studies in humans and animals have generally suggested that chronic hyperinsulinemia facilitates VLDL production, particularly in the presence of an abundant supply of...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:10.2337/diacare.19.4.390
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc12-0428
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To determine whether adults diagnosed with type 2 diabetes from age 18 to 44 years more aggressively develop clinical complications after diagnosis than adults diagnosed at >or=45 years of age. RESEARCH DESIGN AND METHODS:We compared outcomes among 7844 adults in a health maintenance organization who were ne...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.26.11.2999
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVE:To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children. RESEARCH DESIGN AND METHODS:MEDLINE, Web of Science, and PubMed were searched to id...
journal_title:Diabetes care
pub_type: 杂志文章,meta分析
doi:10.2337/diacare.26.9.2568
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To explore the hypothesis that a relationship exists between free radical activity and abnormalities in hemostasis in NIDDM. RESEARCH DESIGN AND METHODS:The use of the total radical-trapping antioxidant parameter (TRAP) has very recently been proposed to explore the antioxidant property of a plasma and their...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.20.10.1589
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:To assess the 12- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 versus placebo in patients with type 2 diabetes continuing metformin treatment. RESEARCH DESIGN AND METHODS:We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 107 patients with type 2 diabetes wi...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.27.12.2874
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To determine contributions of trunk and extremity adiposity to cardiometabolic risk factors (blood pressure, fasting blood glucose, HDL cholesterol, and triglycerides) among white and African American adults. RESEARCH DESIGN AND METHODS:The sample consisted of 1,129 white women, 779 African American women, 1...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-2019
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine whether impaired fasting plasma glucose (FPG) and type 2 diabetes may be risk factors for sudden cardiac death (SCD). RESEARCH DESIGN AND METHODS:This prospective study was based on 2,641 middle-aged men 42-60 years of age at baseline. Impaired FPG level (≥5.6 mmol/L) am...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc12-0110
更新日期:2013-05-01 00:00:00
abstract::A cross-sectional study on the prevalence of atherosclerotic vascular disease (ASVD) and its risk factors in non-insulin-dependent diabetic and nondiabetic subjects was carried out from 1982 to 1984 in East Finland (Kuopio) and West Finland (Turku), two areas known to differ markedly in prevalence of ASVD in the nondi...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.11.6.449
更新日期:1988-06-01 00:00:00
abstract:OBJECTIVE:To determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults wit...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc15-2579
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To determine the value of measuring serum triglyceride (TG) levels early in pregnancy for predicting late-gestation glucose tolerance and neonatal birth weight ratio (BWR) (birth weight corrected for gestational age). RESEARCH DESIGN AND METHODS:The relationships between morning nonfasting TG measured early ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.12.1550
更新日期:1995-12-01 00:00:00
abstract::The results of uncontrolled trials in immunomodulation of insulin-dependent diabetes mellitus (IDDM) led to randomized controlled trials in Canada and Europe. In the Canadian open study, the rate of clinical remissions (target control of glycemia maintained with less than or equal to 0.15 U.kg-1.day-1 insulin) was une...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract:OBJECTIVE:The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix metalloproteinase 7 (MMP-7; Matrilysin) are postulated to be biomarkers of renal fibrosis. This study examined an association of circulating levels of ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc20-0630
更新日期:2020-11-01 00:00:00
abstract::Enzymatic electrodes are described for the specific and sensitive determination of glucose in blood. The probes are based on the conversion of B-D-glucose by glucose oxidase chemically attached to the surface of a Pt electrode. The peroxide liberated is sensed by measurement of the current generated at +0.7 volts vs. ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.5.3.181
更新日期:1982-05-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the direct cost incurred by diabetic subjects who were in different income groups in urban and rural India, as well as to examine the changing trends of costs in the urban setting from 1998 to 2005. RESEARCH DESIGN AND METHODS:A total of 556 diabetic subjects from various urban and...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-0144
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To describe market trends for antidiabetic drugs, focusing on newly approved drugs, concomitant use of antidiabetic drugs, and effects of safety concerns and access restrictions on thiazolidinedione use. RESEARCH DESIGN AND METHODS:Nationally projected data on antidiabetic prescriptions for adults dispensed ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc13-2289
更新日期:2014-01-01 00:00:00
abstract::Glucose homeostasis is physiologically maintained by the balance between glucose production by the liver and glucose utilization by the peripheral tissues. Insulin controls hepatic glucose production and promotes glucose utilization by the skeletal muscle. In non-insulin-dependent diabetes mellitus (NIDDM), postabsorp...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:10.2337/diacare.15.3.430
更新日期:1992-03-01 00:00:00