Light-dependent delay in the falling phase of the retinal rod photoresponse.

Abstract:

:Using suction electrodes, photocurrent responses to 100-ms saturating flashes were recorded from isolated retinal rods of the larval-stage tiger salamander (Ambystoma tigrinum). The delay period (Tc) that preceded recovery of the dark current by a criterion amount (3 pA) was analyzed in relation to the flash intensity (If), and to the corresponding fractional bleach (R*0/Rtot) of the visual pigment; R*0/Rtot was compared with R*s/Rtot, the fractional bleach at which the peak level of activated transducin approaches saturation. Over an approximately 8 ln unit range of I(f) that included the predicted value of R*s/Rtot, Tc increased linearly with ln I(f). Within the linear range, the slope of the function yielded an apparent exponential time constant (tau c) of 1.7 +/- 0.2 s (mean +/- S.D.). Background light reduced the value of Tc measured at a given flash intensity but preserved a range over which Tc increased linearly with ln I(f); the linear-range slope was similar to that measured in the absence of background light. The intensity dependence of Tc resembles that of a delay (Td) seen in light-scattering experiments on bovine retinas, which describes the period of essentially complete activation of transducin following a bright flash; the slope of the function relating Td and ln flash intensity is thought to reflect the lifetime of photoactivated visual pigment (R*) (Pepperberg et al., 1988; Kahlert et al., 1990). The present data suggest that the electrophysiological delay has a similar basis in the deactivation kinetics of R*, and that tau c represents TR*, the lifetime of R* in the phototransduction process. The results furthermore suggest a preservation of the "dark-adapted" value of TR* within the investigated range of background intensity.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Pepperberg DR,Cornwall MC,Kahlert M,Hofmann KP,Jin J,Jones GJ,Ripps H

doi

10.1017/s0952523800006441

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

9-18

issue

1

eissn

0952-5238

issn

1469-8714

pii

S0952523800006441

journal_volume

8

pub_type

杂志文章
  • Changes in sensitivity of the dark-adapted eye during concurrent light adaptation of the other eye.

    abstract::Thresholds for detection of light by a dark-adapted test eye were measured while the other, non-test eye was either similarly dark adapted or while it was exposed to an intense red adapting field. An interocular effect that depends on the retinal location of the test was found: compared to the threshold during binocul...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800005095

    authors: Auerbach E,Dörrenhaus A,Cavonius CR

    更新日期:1992-04-01 00:00:00

  • The retinoids of seven species of mantis shrimp.

    abstract::Eyes of stomatopod crustaceans, or mantis shrimps, contain the greatest diversity of visual pigments yet described in any species, with as many as ten or more spectral classes present in a single retina. In this study, the eyes of seven species of mantis shrimp from three superfamilies of stomatopods were examined for...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252380000612x

    authors: Goldsmith TH,Cronin TW

    更新日期:1993-09-01 00:00:00

  • The color of night: Surface color perception under dim illuminations.

    abstract::Several studies document rudimentary color vision under dim illumination. Here, hue perceptions of paper color samples were determined for a wide range of light levels, including very low light levels where rods alone mediate vision. The appearances of 24 paper color samples from the OSA Uniform Color Scales were gaug...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806233492

    authors: Pokorny J,Lutze M,Cao D,Zele AJ

    更新日期:2006-05-01 00:00:00

  • Visual responsiveness and direction selectivity of cells in area 18 during local reversible inactivation of area 17 in cats.

    abstract::We have investigated the effects of inactivation of localized sites in area 17 on the visual responses of cells in visuotopically corresponding regions of area 18. Experiments were performed on adult normal cats. The striate cortex was inactivated by the injection of nanoliters of lidocaine hydrochloride or of gamma-a...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001826

    authors: Casanova C,Michaud Y,Morin C,McKinley PA,Molotchnikoff S

    更新日期:1992-12-01 00:00:00

  • Contrast encoding in retinal bipolar cells: current vs. voltage.

    abstract::To investigate the influence of voltage-sensitive conductances in shaping light-evoked responses of retinal bipolar cells, whole-cell recordings were made in the slice preparation of the tiger salamander, Ambystoma tigrinum. To study contrast encoding, the retina was stimulated with 0.5-s steps of negative and positiv...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523803201036

    authors: Thoreson WB,Burkhardt DA

    更新日期:2003-01-01 00:00:00

  • How many pixels make an image?

    abstract::The human visual system is remarkably tolerant to degradation in image resolution: human performance in scene categorization remains high no matter whether low-resolution images or multimegapixel images are used. This observation raises the question of how many pixels are required to form a meaningful representation o...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080930

    authors: Torralba A

    更新日期:2009-01-01 00:00:00

  • AMPA-selective glutamate receptor subunits GluR2 and GluR4 in the cat retina: an immunocytochemical study.

    abstract::AMPA-selective glutamate receptors play a major role in glutamatergic neurotransmission in the retina and are expressed in a variety of neuronal subpopulations. In the present study, immunocytochemical techniques were used to visualize the distribution of GluR2 and GluR4 subunits in the cat retina. Results were compar...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523899166100

    authors: Qin P,Pourcho RG

    更新日期:1999-11-01 00:00:00

  • Computation of motion direction by quail retinal ganglion cells that have a nonconcentric receptive field.

    abstract::One type of retinal ganglion cells prefers object motion in a particular direction. Neuronal mechanisms for the computation of motion direction are still unknown. We quantitatively mapped excitatory and inhibitory regions of receptive fields for directionally selective retinal ganglion cells in the Japanese quail, and...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800172086

    authors: Uchiyama H,Kanaya T,Sonohata S

    更新日期:2000-03-01 00:00:00

  • Variety of genotypes in males diagnosed as dichromatic on a conventional clinical anomaloscope.

    abstract::The hypothesis that dichromatic behavior on a clinical anomaloscope can be explained by the complement and arrangement of the long- (L) and middle-wavelength (M) pigment genes was tested. It was predicted that dichromacy is associated with an X-chromosome pigment gene array capable of producing only a single functiona...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523804213293

    authors: Neitz M,Carroll J,Renner A,Knau H,Werner JS,Neitz J

    更新日期:2004-05-01 00:00:00

  • Pattern-reversal electroretinogram in response to chromatic stimuli: I. Humans.

    abstract::We have studied the steady-state PERG in human subjects in response to red-green plaid patterns modulated either in luminance or in chromaticity or both. By varying the relative luminance of the red and green components, a value could be obtained at which the PERG amplitude was either minimum or locally maximum. This ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800003825

    authors: Morrone C,Porciatti V,Fiorentini A,Burr DC

    更新日期:1994-09-01 00:00:00

  • On the distribution of gamma cells in the cat retina.

    abstract::Ganglion cells of the cat retina that are neither alpha nor beta cells are often lumped for convenience into a single anatomical group--the gamma cells (Boycott & Wässle, 1974; Stone, 1983; Wässle & Boycott, 1991). Defined in this way, gamma cells are the morphological counterpart to the physiological W-cell class, wh...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252380000897x

    authors: Stein JJ,Berson DM

    更新日期:1995-07-01 00:00:00

  • Chromatic detection and discrimination in the periphery: a postreceptoral loss of color sensitivity.

    abstract::The peripheral visual field is marked by a deterioration in color sensitivity, sometimes attributed to the random wiring of midget bipolar cells to cone photoreceptors in the peripheral retina (Mullen, 1991; Mullen & Kingdom, 1996). Using psychophysical methods, we explored differences in the sensitivity of peripheral...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523803205058

    authors: Newton JR,Eskew RT Jr

    更新日期:2003-09-01 00:00:00

  • Simulation of an anatomically defined local circuit: the cone-horizontal cell network in cat retina.

    abstract::The outer plexiform layer of the retina contains a neural circuit in which cone synaptic terminals are electrically coupled and release glutamate onto wide-field and narrow-field horizontal cells. These are also electrically coupled and feed back through a GABAergic synapse to cones. In cat this circuit's structure is...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800008440

    authors: Smith RG

    更新日期:1995-05-01 00:00:00

  • Contrast discrimination: a model and a hypothesis concerning the role of cholinergic modulation in contrast perception.

    abstract::A model of contrast discrimination performance in human observers is developed and then extended to cover effects on performance of anticholinergic drugs. It is shown that it is necessary to assume that neural noise increases at high spatial frequencies in order to provide a satisfactory model of variations in discrim...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800009123

    authors: Smith AT

    更新日期:1996-09-01 00:00:00

  • Cholera toxin mapping of retinal projections in pigeons (Columbia livia), with emphasis on retinohypothalamic connections.

    abstract::Anterograde transport of cholera toxin subunit B (CTb) was used to study the retinal projections in birds, with an emphasis on retinohypothalamic connections. Pigeons (Columbia livia) were deeply anesthetized and received unilateral intraocular injections of CTb. In addition to known contralateral retinorecipient regi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800002376

    authors: Shimizu T,Cox K,Karten HJ,Britto LR

    更新日期:1994-05-01 00:00:00

  • Alpha ganglion cells of the rabbit retina lose antagonistic surround responses under dark adaptation.

    abstract::Alpha ganglion cells from the midperiphery of the rabbit retina were recorded intracellularly under visual control, in a superfused everted eyecup, and labeled with HRP. Their physiology and large somata with broad dendritic arbors identified them as uniform populations of ON- and OFF-center alpha ganglion cells, whic...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800011512

    authors: Muller JF,Dacheux RF

    更新日期:1997-03-01 00:00:00

  • Cell density ratios in a foveal patch in macaque retina.

    abstract::We examine the assumptions that the fovea contains equal numbers of inner (invaginating or ON) and outer (flat or OFF) midget bipolar cells and equal numbers of inner and outer diffuse bipolar cells. Based on reconstruction from electron photomicrographs of serial thin sections through the fovea of a macaque monkey, w...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523803202091

    authors: Ahmad KM,Klug K,Herr S,Sterling P,Schein S

    更新日期:2003-03-01 00:00:00

  • A novel system for the classification of diseased retinal ganglion cells.

    abstract::Retinal ganglion cell (RGC) dendritic atrophy is an early feature of many forms of retinal degeneration, providing a challenge to RGC classification. The characterization of these changes is complicated by the possibility that selective labeling of any particular class can confound the estimation of dendritic remodeli...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523814000248

    authors: Tribble JR,Cross SD,Samsel PA,Sengpiel F,Morgan JE

    更新日期:2014-11-01 00:00:00

  • Receptor targets of amacrine cells.

    abstract::Amacrine cells are a morphologically and functionally diverse group of inhibitory interneurons. Morphologically, they have been divided into approximately 30 types. Although this diversity is probably important to the fine structure and function of the retinal circuit, the amacrine cells have been more generally divid...

    journal_title:Visual neuroscience

    pub_type: 杂志文章,评审

    doi:10.1017/S0952523812000028

    authors: Zhang C,McCall MA

    更新日期:2012-01-01 00:00:00

  • Reaction time measures of adaptation to chromatic contrast.

    abstract::Simple reaction times (RTs) were measured to brief temporally blurred (total onset 570 ms) Gaussian isoluminant chromatic patches (s.d. 0.5 degrees) whose chromaticities lay along the cardinal chromatic axes (0 degrees, 90 degrees, 180 degrees, and 270 degrees in MBDKL color space). Bipolar adapting stimuli were emplo...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080449

    authors: Parry NR,Murray IJ,McKeefry DJ

    更新日期:2008-05-01 00:00:00

  • A phenomenological model of visually evoked spike trains in cat geniculate nonlagged X-cells.

    abstract::The visual information that first-order cortical cells receive is contained in the visually evoked spike trains of geniculate relay cells. To address functional issues such as the ON/OFF structure of visual cortical receptive fields with modelling studies, a geniculate cell model is needed where the spatial and tempor...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523898156158

    authors: Gazères N,Borg-Graham LJ,Frégnac Y

    更新日期:1998-11-01 00:00:00

  • Differential effects of excitatory amino acids on photoreceptors of the chick retina: an electron-microscopical study using the zinc-iodide-osmium technique.

    abstract::Although excitotoxins derived from acidic amino acids are known to damage neurons in the inner nuclear and ganglion cell layers of the retina, little is known about their effects on photoreceptors. This study examines the acute and long-term effects of excitotoxins on photoreceptors of the chick retina. The zinc-iodid...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001152

    authors: Sattayasai J,Zappia J,Ehrlich D

    更新日期:1989-01-01 00:00:00

  • Transitions between color categories mapped with a reverse Stroop task.

    abstract::In the reverse Stroop task, observers are instructed to ignore the ink color in which a color word is printed (the distractor color) and to respond to the meaning of the color word (the target). Reaction times (RTs) are faster with congruent combinations when the ink color matches the word than with incongruent combin...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806233388

    authors: Smithson HE,Khan SS,Sharpe LT,Stockman A

    更新日期:2006-05-01 00:00:00

  • Central factors contributing to para-contrast modulation of contour and brightness perception.

    abstract::Following up on a prior study of contour and brightness processing in visual masking (Breitmeyer et al., 2006), we investigated the effects of a binocular and dichoptic para-contrast masking on the visibility of the contour and brightness of a target presented to the other eye. Combined, the results support the contri...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523807070393

    authors: Breitmeyer BG,Ziegler R,Hauske G

    更新日期:2007-03-01 00:00:00

  • Evoked potential and psychophysical analysis of Fourier and non-Fourier motion mechanisms.

    abstract::Some visual stimuli produce a strong percept of motion, even though they fail to excite motion detectors based on Fourier energy or cross correlation. Models which suffice to explain the motion percept in these non-Fourier motion (NFM) stimuli include linear spatiotemporal filtering, followed by rectification, followe...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800009573

    authors: Victor JD,Conte MM

    更新日期:1992-08-01 00:00:00

  • The brain-stem parabrachial region controls mode of response to visual stimulation of neurons in the cat's lateral geniculate nucleus.

    abstract::We recorded the responses of neurons from the cat's lateral geniculate nucleus to drifting sine-wave grating stimuli both before and during electrical stimulation of the parabrachial region of the midbrain. The parabrachial region provides a mostly cholinergic input to the lateral geniculate nucleus, and our goal was ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800005332

    authors: Lu SM,Guido W,Sherman SM

    更新日期:1993-07-01 00:00:00

  • Photoresponses of human rods in vivo derived from paired-flash electroretinograms.

    abstract::In the human eye, domination of the electroretinogram (ERG) by the b-wave and other postreceptor components ordinarily obscures all but the first few milliseconds of the rod photoreceptor response to a stimulating flash. However, recovery of the rod response after a bright rest flash can be analyzed using a paired-fla...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800008774

    authors: Pepperberg DR,Birch DG,Hood DC

    更新日期:1997-01-01 00:00:00

  • Antidromic latency of magnocellular, parvocellular, and koniocellular (Blue-ON) geniculocortical relay cells in marmosets.

    abstract::We studied the functional connectivity of cells in the lateral geniculate nucleus (LGN) with the primary visual cortex (V1) in anesthetized marmosets (Callithrix jacchus). The LGN sends signals to V1 along parallel visual pathways called parvocellular (P), magnocellular (M), and koniocellular (K). To better understand...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523814000066

    authors: Cheong SK,Johannes Pietersen AN

    更新日期:2014-05-01 00:00:00

  • Comparative structural and functional analysis of photoreceptor neurons of Rho-/- mice reveal increased survival on C57BL/6J in comparison to 129Sv genetic background.

    abstract::To explore the possible influence of defined genetic backgrounds on photoreceptor viability and function in mice carrying a targeted disruption of the rhodopsin gene, the severities of retinopathies in Rho-/- mice on C57BL/6J and 129Sv congenic backgrounds were compared by light microscopy and electroretinography and ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801183100

    authors: Humphries MM,Kiang S,McNally N,Donovan MA,Sieving PA,Bush RA,Machida S,Cotter T,Hobson A,Farrar J,Humphries P,Kenna P

    更新日期:2001-05-01 00:00:00

  • Controversies about the visual areas located at the anterior border of area V2 in primates.

    abstract::Anatomical and electrophysiological studies have provided us with detailed information regarding the extent and topography of the primary (V1) and secondary (V2) visual areas in primates. The consensus about the V1 and V2 maps, however, is in sharp contrast with controversies regarding the organization of the cortical...

    journal_title:Visual neuroscience

    pub_type: 杂志文章,评审

    doi:10.1017/S0952523815000188

    authors: Gattass R,Lima B,Soares JG,Ungerleider LG

    更新日期:2015-01-01 00:00:00