Abstract:
:Circadian rhythms are entrained to the natural day:night cycle. Melanopsin expressed in retinal ganglion cells partially accounts for circadian photoentrainment. Dkhissi-Benyahya et al. demonstrate that medium wavelength opsin (MW-opsin) also plays an important role in the process. Furthermore, they develop a model explaining wavelength-dependent photoentrainment by melanopsin and MW-opsin.
journal_name
Neuronjournal_title
Neuronauthors
Panda Sdoi
10.1016/j.neuron.2007.02.017subject
Has Abstractpub_date
2007-03-01 00:00:00pages
619-21issue
5eissn
0896-6273issn
1097-4199pii
S0896-6273(07)00136-5journal_volume
53pub_type
评论,杂志文章,评审相关文献
NEURON文献大全abstract::Oxygen (O₂) and carbon dioxide (CO₂) levels vary in different environments and locally fluctuate during respiration and photosynthesis. Recent studies in diverse animals have identified sensory neurons that detect these external variations and direct a variety of behaviors. Detection allows animals to stay within a pr...
journal_title:Neuron
pub_type: 杂志文章,评审
doi:10.1016/j.neuron.2010.12.018
更新日期:2011-01-27 00:00:00
abstract::The link between dysregulated serotonergic activity and depression and anxiety disorders is well established, yet the molecular mechanisms underlying these psychopathologies are not fully understood. Here, we explore the role of microRNAs in regulating serotonergic (5HT) neuron activity. To this end, we determined the...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2014.05.042
更新日期:2014-07-16 00:00:00
abstract::Neural representations of head direction (HD) have been discovered in many species. Theoretical work has proposed that the dynamics associated with these representations are generated, maintained, and updated by recurrent network structures called ring attractors. We evaluated this theorized structure-function relatio...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2020.08.006
更新日期:2020-10-14 00:00:00
abstract::Recent evidence has challenged the view that memories are made permanent by a consolidation process that happens just once and instead have suggested that memories are "re-consolidated" after reminders. The current findings of Morris et al. in this issue of Neuron suggest that reconsolidation may involve a complex int...
journal_title:Neuron
pub_type: 评论,杂志文章,评审
doi:10.1016/j.neuron.2006.04.017
更新日期:2006-05-04 00:00:00
abstract::Long non-coding RNAs (lncRNAs) are a diverse and poorly conserved category of transcripts that have expanded greatly in primates, particularly in the brain. We identified an lncRNA, which has acquired 16 microRNA response elements for miR-143-3p in the Catarrhini branch of primates. This lncRNA, termed LncND (neurodev...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2016.05.005
更新日期:2016-06-15 00:00:00
abstract::Spine Ca(2+) is critical for the induction of synaptic plasticity, but the factors that control Ca(2+) handling in dendritic spines under physiological conditions are largely unknown. We studied [Ca(2+)] signaling in dendritic spines of CA1 pyramidal neurons and find that spines are specialized structures with low end...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(02)00573-1
更新日期:2002-01-31 00:00:00
abstract::A longstanding debate in binocular rivalry literature is whether the perceptual competition in rivalry occurs at an early or late stage of visual processing. Central to this debate is the determination of the source of the competition. Overwhelming evidence exists that local interocular differences can lead to binocul...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2004.08.039
更新日期:2004-09-16 00:00:00
abstract::GABAergic, somatostatin-containing bitufted interneurons in layer 2/3 of rat neocortex are excited via glutamatergic excitatory postsynaptic potentials (EPSPs) by pyramidal neurons located in the same cortical layer. Pair recordings showed that short bursts of backpropagating dendritic action potentials (APs) reduced ...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)81044-2
更新日期:1999-12-01 00:00:00
abstract::For efficient coding, sensory systems need to adapt to the distribution of signals to which they are exposed. In vision, natural scenes above and below the horizon differ in the distribution of chromatic and achromatic features. Consequently, many species differentially sample light in the sky and on the ground using ...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2013.09.030
更新日期:2013-12-04 00:00:00
abstract::Using exome sequencing, we identified a p.R191Q amino acid change in the valosin-containing protein (VCP) gene in an Italian family with autosomal dominantly inherited amyotrophic lateral sclerosis (ALS). Mutations in VCP have previously been identified in families with Inclusion Body Myopathy, Paget disease, and Fron...
journal_title:Neuron
pub_type: 杂志文章,多中心研究
doi:10.1016/j.neuron.2010.11.036
更新日期:2010-12-09 00:00:00
abstract::Recent advances in military-funded neurotechnology and novel opportunities for misusing neurodevices show that the problem of dual use is inherent to neuroscience. This paper discusses how the neuroscience community should respond to these dilemmas and delineates a neuroscience-specific biosecurity framework. This neu...
journal_title:Neuron
pub_type: 杂志文章,评审
doi:10.1016/j.neuron.2017.12.017
更新日期:2018-01-17 00:00:00
abstract::We have cloned from the receptor epithelium of the chick cochlea a family of alternatively spliced cDNAs derived from cslo, which encodes a Ca2+-activated K+ channel like those shown to help determine the resonant frequency of electrically tuned hair cells. Our results from PCRs using template RNAs from both tonotopic...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)80398-0
更新日期:1997-11-01 00:00:00
abstract::We examined the contribution of the amygdala to value signals within orbital prefrontal cortex (OFC) and medial prefrontal cortex (MFC). On each trial, monkeys chose between two stimuli that were associated with different quantities of reward. In intact monkeys, as expected, neurons in both OFC and MFC signaled the re...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2013.09.036
更新日期:2013-12-18 00:00:00
abstract::The brain must make sense of external stimuli to generate relevant behavior. We used a combination of in vivo approaches to investigate how the cerebellum processes sensory-related information. We found that the inferior olive encodes contexts of sensory-associated external cues in a graded manner, apparent in the pre...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2019.03.010
更新日期:2019-05-22 00:00:00
abstract::In the visual cortex of many mammals, orientation preference changes smoothly along the cortical surface, with the exception of singularities such as pinwheels and fractures. The reason for the existence of these singularities has remained elusive, suggesting that they are developmental artifacts. We show that singula...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(01)00223-9
更新日期:2001-02-01 00:00:00
abstract::Our perception of fine visual detail relies on small receptive fields at early stages of visual processing. However, small receptive fields tend to confound the orientation and velocity of moving edges, leading to ambiguous or inaccurate motion measurements (the aperture problem). Thus, it is often assumed that neuron...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(03)00439-2
更新日期:2003-08-14 00:00:00
abstract::Antibodies were raised to three portions of the predicted sequences of Shaker, a gene that encodes a family of K+ channel components that are produced by the alternative splicing of transcripts. On immunoblots, the protein products appear to be 65,000-85,000 daltons in size. No smaller products were detected. Immunocy...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(90)90448-o
更新日期:1990-01-01 00:00:00
abstract::The spatial receptive fields of neurons in medial entorhinal cortex layer II (MECII) and in the hippocampus suggest general and environment-specific maps of space, respectively. However, the relationship between these receptive fields remains unclear. We reversibly manipulated the activity of MECII neurons via chemoge...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2017.03.001
更新日期:2017-03-22 00:00:00
abstract::The mechanisms controlling the transition from neurogenesis to gliogenesis in the vertebrate CNS are incompletely understood. We identified a family of transcription factors, called NFI genes, which are induced throughout the spinal cord ventricular zone (VZ) concomitantly with the induction of GLAST, an early marker ...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2006.11.019
更新日期:2006-12-21 00:00:00
abstract::We have examined the role of presynaptic residual calcium in maintaining long-term changes in synaptic efficacy observed at mossy fiber synapses between hippocampal dentate granule cells and CA3 pyramidal cells. Calcium concentrations in individual mossy fiber terminals in hippocampal slice were optically measured wit...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(91)90297-d
更新日期:1991-09-01 00:00:00
abstract::The concept of the CNS as an immune-privileged organ has led to a common misunderstanding that it is not an active immunological organ, guarded from its surroundings by the blood-brain barrier (BBB). Recent advances in this field clearly demonstrate that the CNS is a highly immunologically active organ, with complex i...
journal_title:Neuron
pub_type: 杂志文章,评审
doi:10.1016/j.neuron.2013.04.005
更新日期:2013-04-24 00:00:00
abstract::Retinal specializations such as cone-photoreceptor opsin-expression gradients, as found in several vertebrate species, are intuitively considered detrimental to color vision. In mice, the majority of cones coexpress both "blue" and "green" opsin. The coexpression ratio changes along the dorsoventral axis, resulting in...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2012.12.012
更新日期:2013-02-06 00:00:00
abstract::The distribution of the synaptic vesicle-associated phosphoprotein synapsin I after electrical stimulation of the frog neuromuscular junction was investigated by immunogold labeling and compared with the distribution of the integral synaptic vesicle protein synaptophysin. In resting terminals both proteins were locali...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(92)90072-l
更新日期:1992-12-01 00:00:00
abstract::During the metamorphosis of the Xenopus laevis retina, thyroid hormone (TH) preferentially induces ventral ciliary marginal zone (CMZ) cells to both increase their proliferation and give rise to ipsilaterally projecting ganglion cells. Here we show that dorsal CMZ cells express type III deiodinase (D3), an enzyme that...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)81034-x
更新日期:1999-12-01 00:00:00
abstract::Negative affective states affect quality of life for patients suffering from pain. These maladaptive emotional states can lead to involuntary opioid overdose and many neuropsychiatric comorbidities. Uncovering the mechanisms responsible for pain-induced negative affect is critical in addressing these comorbid outcomes...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2019.02.029
更新日期:2019-05-08 00:00:00
abstract::Although associative learning has been localized to specific brain areas in many animals, identifying the underlying synaptic processes in vivo has been difficult. Here, we provide the first demonstration of long-term synaptic plasticity at the output site of the Drosophila mushroom body. Pairing an odor with activati...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2015.11.003
更新日期:2015-12-02 00:00:00
abstract::alpha-Latrotoxin is a potent stimulator of neurosecretion. Its action requires extracellular binding to high affinity presynaptic receptors. Neurexin I alpha was previously described as a high affinity alpha-latrotoxin receptor that binds the toxin only in the presence of calcium ions. Therefore, the interaction of al...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)80332-3
更新日期:1997-06-01 00:00:00
abstract::Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are key modulators of neuronal activity by providing the depolarizing cation current I(h) involved in rhythmogenesis, dendritic integration, and synaptic transmission. These tasks critically depend on the availability of HCN channels, which is dynamica...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2009.05.008
更新日期:2009-06-25 00:00:00
abstract::Balance between excitation and inhibition (E-I balance) in neural circuits is believed to be tightly regulated. To the contrary, in this issue of Neuron, Bridi et al. (2020) reveal that inverse oscillations of synaptic inhibition and excitation lead to peaks and valleys in E-I balance across the 24 h day. ...
journal_title:Neuron
pub_type: 评论,杂志文章
doi:10.1016/j.neuron.2020.01.035
更新日期:2020-02-19 00:00:00
abstract::In this issue of Neuron, Ajemian et al. present a computational model of the activity of neurons in primary motor cortex (M1) during isometric movements in different postures. By modeling the output of M1 neurons in terms of their influence on muscles, they find each M1 neuron maps its output into a particular pattern...
journal_title:Neuron
pub_type: 评论,杂志文章,评审
doi:10.1016/j.neuron.2008.04.022
更新日期:2008-05-08 00:00:00