Abstract:
:Direct infection of muscle fibers by human T-lymphotropic virus type I (HTLV-I) has recently been reported in a patient with polymyositis infected with both HTLV-I and human immunodeficiency virus (HIV). Coinfections of these viruses are frequently found in the United States. In Kagoshima, Japan, patients with polymyositis have a significantly increased incidence of seropositivity to HTLV-I alone, when compared with the general population of Kagoshima. In this study, we examined muscle tissue from 6 HTLV-I-positive patients with polymyositis from Kagoshima. To detect HTLV-I products, sensitive immunohistochemistry and in situ hybridization analysis were performed. These were compared with muscle fibers from a well-characterized transgenic mouse model which expressed HTLV-I tax. No specific signals were detected in the biopsied muscles of patients with polymyositis infected with HTLV-I alone. HIV co-infection may, therefore, augment HTLV-I expression through either immunosuppression or direct viral interactions.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Higuchi I,Nerenberg M,Yoshimine K,Yoshida M,Fukunaga H,Tajima K,Osame Mdoi
10.1002/mus.880150108subject
Has Abstractpub_date
1992-01-01 00:00:00pages
43-7issue
1eissn
0148-639Xissn
1097-4598journal_volume
15pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract::Evaluation of the precise molecular dynamics of endplate maintenance and reorganization has been limited by the lack of available in vitro preparations. We describe an organ culture preparation of mouse diaphragm muscle which permits long-term maintenance of muscle viability. Spontaneous fibrillations, increased level...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880141012
更新日期:1991-10-01 00:00:00
abstract::Nemaline myopathy is a rare disorder of varying severity and genetic etiology. We present two cases, a father and son, with a novel missense mutation in the alpha actin gene. Both have a history of early motor impairment, with the son's course being considerably more severe. This pair illustrates the clinical variabil...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20662
更新日期:2007-02-01 00:00:00
abstract:INTRODUCTION:Rapid and accessible methods for diagnosing diabetic polyneuropathy (DPN) have been developed, but not validated, in large cohorts of people with diabetes. METHODS:The performance of a point-of-care device (POCD) was studied in 168 patients with type 2 diabetes, estimating the sensitivity, specificity, po...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26361
更新日期:2019-02-01 00:00:00
abstract::Although conduction block indicates dysfunction of peripheral nerve, it may occur in patients with clinically typical motor neuron disease. There are no universally accepted criteria to identify conduction block, so diagnosis may be difficult. In some peripheral neuropathies, conduction block persists over long period...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880160903
更新日期:1993-09-01 00:00:00
abstract:INTRODUCTION:The immuno-microenvironment of injured nerves adversely affects mesenchymal stem cell (MSC) therapy for neurotmesis. Magnetic resonance imaging (MRI) can be used noninvasively to monitor nerve degeneration and regeneration. The aim of this study was to investigate nerve repair after MSC transplantation com...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26862
更新日期:2020-06-01 00:00:00
abstract::The aim of this study was to investigate possible influences of suprasegmental lesions on the masseter reflex. The masseter reflex was elicited in 54 patients with supratentorial (37 patients) or cerebellar (17 patients) lesions 3-11 days after the acute onset of clinical disease. Patients showing lesions within the p...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-4598(200001)23:1<86::aid-mus11>
更新日期:2000-01-01 00:00:00
abstract::Two sisters presented with distal weakness and their muscle biopsy was dystrophic. This distal muscular dystrophy has an autosomal recessive inheritance and its features are somewhat different from the more common autosomal dominant distal muscular dystrophy and include: a) onset in early adult life; b) involvement of...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880070610
更新日期:1984-07-01 00:00:00
abstract:INTRODUCTION:Full-length tyrosine kinase B (TrkB.FL) and truncated TrkB (TrkB.t1) receptors are colocalized with acetylcholine receptors (AChRs) at the neuromuscular junction. We have recently shown that reduced TrkB expression leads to age-related alterations in AChR structure, neurotransmission failure, and muscle we...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23616
更新日期:2013-04-01 00:00:00
abstract::Sucrose gap and intra-axonal recording techniques were used to identify the types of ion channels and inward rectification that are present in regenerated axons of adult (greater than 8 weeks) rat sciatic nerve after crush injury. In sucrose gap recordings, 4-aminopyridine (4-AP) led to slight broadening of the compou...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880140707
更新日期:1991-07-01 00:00:00
abstract:INTRODUCTION:Evaluation of phrenic neuropathy (PN) with phrenic nerve conduction studies (PNCS) is associated with false negatives. Visualization of diaphragmatic muscle twitch with diaphragm ultrasound (DUS) when performing PNCS may help to solve this problem. METHODS:We performed bilateral, simultaneous DUS-PNCS in ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24059
更新日期:2014-05-01 00:00:00
abstract::To better define electrophysiological abnormalities in myasthenia gravis (MG) patients with muscle-specific tyrosine kinase (MuSK) antibodies (Ab), we compared electrophysiological features of 14 MuSK Ab-positive, 73 acetylcholine receptor antibody (AChR Ab)-positive, and 22 MuSK and AChR Ab-negative (seronegative) pa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20498
更新日期:2006-04-01 00:00:00
abstract::Clinicopathologic findings from two golden retriever dogs with an inherited, progressive, degenerative muscle disease that were studied until 27 and 40 months of age are described. Initial clinical signs included stilted gait and simultaneous advancement of their pelvic limbs. Further gait restriction and muscle hyper...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880111008
更新日期:1988-10-01 00:00:00
abstract:INTRODUCTION:We sought to translate, culturally adapt, and assess the Arabic version of the 15-item myasthenia gravis quality-of-life revised scale (MGQOL15R). METHODS:We assessed reliability with Cronbach α; reproducibility with intraclass correlation coefficient (ICC); validity with Spearman correlations for myasthe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25948
更新日期:2018-04-01 00:00:00
abstract::We describe a patient with transthyretin amyloidosis who presented with multifocal mononeuropathies with features of demyelination on nerve conduction studies, a constellation of findings not previously described in amyloid polyneuropathy. Genetic testing revealed a valine122isoleucine mutation in the coding region of...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10614
更新日期:2004-02-01 00:00:00
abstract:INTRODUCTION:Voltage-gated Kv1 potassium channel complex (VGKC) autoantibodies subtyped for leucine-rich glioma-inactivated 1 (LGI1), contactin-associated-proteinlike 2 (CASPR2), and Kv IgGs have a spectrum of neurological presentations. Painful polyneuropathy is seen in some patients, but nerve pathology descriptions ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25371
更新日期:2017-04-01 00:00:00
abstract:INTRODUCTION:POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes) syndrome may be mistaken for chronic inflammatory demyelinating polyneuropathy (CIDP). Differentiating the 2 entities is crucial, as there are major treatment implications. METHODS:We compared platelet ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24768
更新日期:2015-10-01 00:00:00
abstract::Exercise intolerance with myalgia, muscle stiffness, and recurrent rhabdomyolysis due to mutations in the DMD gene can mimic metabolic myopathies leading to delayed or inaccurate diagnoses. In this retrospective chart review, we report 3 unrelated boys with exertional myalgia, muscle stiffness, myoglobinuria, and norm...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21823
更新日期:2010-12-01 00:00:00
abstract::Frog muscles bathed in solutions equilibrated with 0.5%-2.0% halothane develop large contractures when cooled to 2-4 degrees C. These halothane-cooling contractures (HCC) are dose dependent and reproducible; they are potentiated by lidocaine (5 mM), abolished by procaine (5 mM), and partially inhibited by procainamide...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880090107
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:We assessed antibodies against low-density lipoprotein receptor-related protein 4 (LRP4-Ab) in a Chinese population with myasthenia gravis (MG). METHODS:Serum samples from 116 patients and 80 controls were collected. Acetylcholine receptor antibodies(AChR-Ab) and muscle-specific receptor tyrosine kinase a...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25591
更新日期:2017-11-01 00:00:00
abstract::Reinnervation of a free muscle graft by nerves from an adjacent intact muscle is called muscular neurotization. This paper investigates the mechanisms and stimuli responsible for muscular neurotization in the rat. Sternohyoid or sternomastoid muscles were transplanted as free muscle grafts to the ventral surface of an...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880100607
更新日期:1987-07-01 00:00:00
abstract:INTRODUCTION:Evaluation of nerve mechanical properties has the potential to improve assessment of nerve impairment. Shear wave velocity, as measured by using shear wave (SW) ultrasound elastography, is a promising indicator of nerve mechanical properties such as stiffness. However, elucidation of external factors that ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26842
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:Electrical stimulation of denervated muscle has been shown to minimize atrophy and fibrosis and increase force in animal and human models. However, electrical stimulation after nerve repair is controversial due to questions of efficacy. METHODS:Using a rat model, we investigated the efficacy of short-term...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23726
更新日期:2013-08-01 00:00:00
abstract::Recent studies on the distribution of labeled endogenous proteins in the experimental neuropathies induced by streoptozotocin diabetes, galactose feeding, zinc pyridinethione, 2,5-hexanedione, acrylamide, and p-bromophenylacetylurea (BPAU) have demonstrated an impaired build up of retrogradely transported material der...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880060214
更新日期:1983-02-01 00:00:00
abstract::Piriformis syndrome (PS) is a rare condition characterized by pain and paresthesia of the buttock, often radiating to the posterior thigh. A patient with sciatica that was clinically suspicious for PS, underwent diagnostic work-up. A diagnosis of diffuse large B-cell lymphoma with neurolymphomatosis (NL) was made. To ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21538
更新日期:2010-03-01 00:00:00
abstract::Focal myositis is a rare inflammatory pseudotumor of skeletal muscle which usually has a benign course. We report a 56-year-old woman with a painful mass in the left arm with a radial nerve palsy. Magnetic resonance imaging (MRI) of the left arm showed a mass in the triceps muscle that was suggestive of a soft-tissue ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199907)22:7<956::aid-mus25
更新日期:1999-07-01 00:00:00
abstract::The absolute number of satellite cells (SC) in young and adult rat skeletal muscle was estimated by correlating data from light and electron microscopic quantitation of myofiber nuclei (myonuclei and satellite cell nuclei) with biochemical assays for determining total muscle DNA content. Expressed both as a proportion...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880060807
更新日期:1983-10-01 00:00:00
abstract:INTRODUCTION:Topical application of lidocaine-and-prilocaine (LP) cream attenuates the functionality of small cutaneous nerve fibers. The aim of this human study was to measure the underlying excitability modulation of small cutaneous nerve fibers using a novel and fast perception threshold tracking (PTT) technique. M...
journal_title:Muscle & nerve
pub_type: 杂志文章,随机对照试验
doi:10.1002/mus.26520
更新日期:2019-10-01 00:00:00
abstract::We report an 18-month-old Charcot-Marie-Tooth type 1A (CMT1A) patient who developed a rapid-onset neuropathy, with proximal and distal weakness, and non-uniform nerve conduction studies. The neuropathy responded well to immunomodulation, confirming the coexistence of an inherited and an inflammatory neuropathy. Unexpe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21753
更新日期:2010-10-01 00:00:00
abstract::Repetitive nerve stimulation (RNS) of the median nerve is rarely studied in myasthenia gravis (MG). We performed a retrospective analysis of RNS studies performed on 448 patients at our center between 2010 and 2016. Among 95 patients with MG, an abnormal decrement of the compound muscle action potential amplitude was ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26713
更新日期:2019-12-01 00:00:00
abstract::Muscular dystrophy is defined as the progressive wasting of skeletal muscles that is caused by inherited or spontaneous genetic mutations. Next-generation sequencing has greatly improved the accuracy and speed of diagnosis for different types of muscular dystrophy. Advancements in depth of coverage, convenience, and o...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.25953
更新日期:2018-01-01 00:00:00